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Locating device and its locating method for biochip

A biochip and positioning device technology, which is applied to measurement devices, biological testing, material inspection products, etc., can solve problems such as position deviation and relative distance change of dot pattern, so as to reduce waste, improve manufacturing yield and difficulty. and the effect of improving the error rate

Inactive Publication Date: 2006-06-07
KAIWOOD TECH
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AI Technical Summary

Problems solved by technology

[0012] The present invention is to effectively solve the problem of expansion, shrinkage, skewing or loss of array points in the known technology, and provides a positioning method for biochip dots, which is directly on each individual biochip matrix. Specific reference point positions are marked on the carrier, and then the pattern is printed, and in the process of patterning, the position of each pattern is fed back and corrected by image capture, thus avoiding and improving the size of the biochip carrier in the known technology. Problems caused by differences and incorrect placement of dot pattern position offset, rotation and relative distance change

Method used

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  • Locating device and its locating method for biochip
  • Locating device and its locating method for biochip

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Embodiment Construction

[0025] The techniques, means and effects used in the present invention are described in detail by listing preferred embodiments here.

[0026] In order to achieve the above object, the present invention provides a positioning device (1) (such as figure 1 As shown), it includes an image capture device (10) and a position adjustment system (12). The image capture device (10) is used to capture and record the positions of the reference points and pattern points of the biochip carrier, and the alignment adjustment system (12) is based on the reference points obtained by the image capture device (10). Dots and the position of the sample point are calculated to calculate the correct position of each sample point, and execute the dot pattern. The positioning device (1) can be arranged at an appropriate position of the dotted pattern system to obtain the most accurate position of the dotted pattern. Wherein, the alignment adjustment system (12) may include a computing unit (14) and ...

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Abstract

The present invention provides locating device and method for biochip sample application. The locating device includes one image pick-up device and one locating regulation system. The method of locating the biological probe in the biochip carrier accurately includes the following steps: A. providing a biochip sample application locating device including one image pick-up device and one locating regulation system; B. marking the reference point on the biochip carrier before sample application; C. picking up and recording the image of the reference point with the image pick-up device; D. calculating the first sample applying position with the locating regulation system and applying sample; E. picking up the image of the sample applying position; F. performing feedback operation and correcting the next sample applying position and applying sample; and G. repeating the steps E and F until completing all the sample application.

Description

technical field [0001] The present invention relates to a positioning device for biochip dotted cloth samples and a positioning method for biochip dotted cloth samples, in particular to marking reference point positions on each individual biochip carrier and using image capture for feedback correction dots Cloth sample positioning device and method. Background technique [0002] The word biochip (biochip) originated in the 1980s. Broadly speaking, it refers to the use of micro-area and high-density technology to precisely place molecules related to biology, such as genes, proteins, carbohydrates or cell tissues, on On a carrier for other applications. The production of biochips requires the use of a variety of industrial technologies, combined with biomedical technology, using the principles of molecular biology, analytical chemistry, and biochemical reactions to design, and to make biomolecules on glass, silicon wafers, plastics (polymer materials), etc. The biochemical a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N21/84
Inventor 庄琮凯王建华李浚荣林淑芬崔美玲
Owner KAIWOOD TECH
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