Application of medication composition of containing notoperygium root in preparing medication for treating chronic insufficiency of supplying blood for brain

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of long-term curative effect needing further study, no focal neurological signs in the brain, etc.

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0056] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. A good short-term clinical effect has been achieved, but the long-term effect needs further study

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Take notopterygium 70g, chuanxiong 90g, uncaria 60g, asarum 60g, ephedra 70g, solitary 70g, angelica 70g, peach kernel 40g, safflower 90g, rehmannia 60g, white peony root 50g, Fangfeng 80g, angelica 60g, notopterygium 55g, solitary 50g.

[0087] Take the medicinal materials according to the above ratio, add water to extract 3 times, each time for 1 hour, combine the extracts, concentrate appropriately, add 2 times the amount of ethanol, let it stand for 24 hours to precipitate, take the supernatant and concentrate it into an extract, the relative density is 1.3~ 1.4, the paste yield is 10%, take clear paste, spray dry into powder. Capsules are made according to a conventional process method.

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PUM

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Abstract

An application of the medicinal composition composed of 13 Chinese-medicinal materials including notopterygium root, Chuan-xiong rhizome, peach kernel, safflower, etc in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing notopterygium in the preparation of a medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis hav...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P9/10A61P9/02
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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