Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

36 results about "Chronic cerebral ischemia" patented technology

Application of kudzuvine root flavone in preparing medicine for treating chronic insufficiency of blood supply for brain

An application of the pueraria flavone in preparing the medicines for treating chronic cerebral ischemia is disclosed. Its preparing process includes such steps as providing pueraris roots, extracting in water or alcohol, concentrating, depositing in alcohol, purifying by chromatography, eluting and spray drying.
Owner:TIANJIN TASLY PHARMA CO LTD

Application of catalpol and retinoic acid medicine composition in preparing medicine used for preventing or treating white matter damage

The invention belongs to the field of medicine, and relates to the field of medicine preparation treatment activity. The invention specifically relates to a catalpol and retinoic acid medicine composition CAT-RA and an application thereof in preparing medicines used for preventing and treating with white matter damage after chronic cerebral ischemia. As a result of experiments of CAT-RA in cells and in chronic cerebral ischemia disease animal models, CAT-RA assists in reducing brain tissue inflammatory responses after brain damage, reducing white matter pathological changes, inhibiting oligodendrocyte apoptosis and myelin damage in white matters, and promoting oligodendrocyte precursor cell differentiation and maturation. CAT-RA has the effects of protecting white matters and promoting white matter remyelination. Therefore, CAT-RA can be used as an active component for preparing medicines used for preventing and treating white matter damage after chronic cerebral ischemia, and can also be used for preparing medicines used for treating other cerebral vascular related diseases characterized in white matter damages. The invention provides a novel solution for prevention and treatment of white matter damage related diseases.
Owner:ARMY MEDICAL UNIV

Diagnostic reagent kit for detecting chronic brain pathologies of ischemic genesis

ActiveUS10408829B2Facilitate subsequent detectionHigh affinityDisease diagnosisCarrier-bound/immobilised peptidesGeneral practionerBrain pathologies
The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.
Owner:OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU DRD

Use of medicinal composition containing red paeony root for preparing medicinefor treating chronic blood shortage to brain

The present invention relates to a medicine composition and its application in preparation of medicine for curing chronic cerebral ischemia. Said medicine composition includes 8 Chinese medicinal materials of 10-20 portions of ginseng, 5-15 portions of red peony root, 6-15 portions of centipede, 10-20 portions of scorpion, 20-30 portions of leech, 10-20 portions of wingless cockroach, 10-20 portions of cicada molting and 2-10 portions of borneol.
Owner:TIANJIN TASLY PHARMA CO LTD

A neural network-based cerebral ischemia risk prediction platform

The invention relates to a neural network-based cerebral ischemia risk estimation platform, which comprehensively considers carotid plaque data and brain magnetic resonance images. ) and obviously abnormal plaques (high risk), leaving carotid plaques that are not easy to judge without obvious stenosis, and then use brain magnetic resonance images to break the conventional perception of carotid plaques themselves. Research to explore the relationship between plaque and brain structure, based on neural network modules, can predict carotid plaques from the initial changes of the brain, and estimate the level of cerebral ischemia risk, which can be used for the assessment of cerebral ischemia risk. It is used for the prediction and prevention of acute stroke, chronic cerebral ischemia, vascular dementia, etc. It is used for clinical prediction. It has a very positive effect on prevention before it occurs. It can improve the accuracy of diagnosis and save the disease to a greater extent and in a timely manner. suffer from life.
Owner:XIANGYA HOSPITAL CENT SOUTH UNIV

Diagnostic reagent kit for detecting chronic brain pathologies of ischemic genesis

ActiveUS20190187133A1Facilitate subsequent detectionHigh affinityDisease diagnosisCarrier-bound/immobilised peptidesGeneral practionerBrain pathologies
The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury.
Owner:OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU DRD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products