Application of kudzuvine root flavone in preparing medicine for treating chronic insufficiency of blood supply for brain

A technology of insufficient cerebral blood supply and pueraria flavonoids, applied in the field of medicine, can solve the problems of long-term curative effect that needs further research, no focal neurological signs in the brain, etc.

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0044] 3. No focal neurological signs of the brain;
[0045] 4. CT\MRI without vascular organic brain changes;
[0057] At present, the drugs used clinically to treat CCCI include: THA: cholinesteras

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] Take 2kg of kudzu powder, add 20L of 60% ethanol to infiltrate, then heat reflux extraction for 3 times, each time for 2 hours, filter, combine the filtrate, concentrate under reduced pressure until there is no alcohol smell, add water to dilute to 10L, and stir at 6.0°C Add 300mL of 1% clarifying agent B solution, stir once every 30 minutes, after 2 hours, add 300mL of 0.5% clarifying agent A solution in the same way, stir again 60 minutes after adding, coarsely filter after 2 hours, and then centrifuge at high speed machine for liquid-solid separation, and take the clarified liquid for later use. Pass above-mentioned clarified solution in the macroporous resin column (4L resin is housed), the total flavonoids of Pueraria radiata will be adsorbed in the resin effectively, wash with 5 10L water until the effluent has no color, then desorb with 15L 50% ethanol, The flow rate of adsorption, washing and desorption is 0.5 times the bed volume per hour. The desorbed solutio...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

An application of the pueraria flavone in preparing the medicines for treating chronic cerebral ischemia is disclosed. Its preparing process includes such steps as providing pueraris roots, extracting in water or alcohol, concentrating, depositing in alcohol, purifying by chromatography, eluting and spray drying.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of kudzu root flavonoids in the preparation of medicines for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have been divergent for a lo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K31/7048A61P9/10A61P9/02A61P25/00
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap