The invention provides a traditional Chinese medicine clysis fluid for treating chronic renal insufficiency and yang deficiency-induced cold of diabetic nephropathy. The traditional Chinese medicine clysis fluid is prepared from the following Chinese herbs: 100g of prepared rhubarb, 100g of dragon's bone, 100g of oyster, 75g of dandelion, 50g of processed radix aconiti lateralis, 50g of cinnamon, 50g of cassia twig, 50g of szechuan lovage rhizome, 50g of safflower, 50g of poria cocos, 50g of agaric, 50g of rose, 50g of hawthorn, 50g of notoginseng powder, 50g of hairyvein agrimonia herband bud, 50g of corydalis tuber, 50g of peach kernel, 50g of root of bidentate achyranthes, suberect spatholobus stem, 50g of dragon's blood, 25g of frankincense, 25g of myrrh, 50g of root of doubleteeth pubescent angelica, 50g of incised notopterygium, 50g of Chinese rose flower, 50g of India mustard seed, 50g of amber powder, 50g of yam rhizome, 50g of thinleaf milkwort root-bark, 50g of silktree albizzia bark, 50g of gecko, 100g of Chinese yam, 75g of manyprickle acanthopanax root, 50g of medicinal Indian mulberry, 50g of walnut kernel, 50g of songaria cynomorium herb, 50g of tuber fleeceflower root, 50g of Chinese angelica, 100g of tortoise shell, 100g of turtle shell, 50g of malaytea scurfpea fruit and 100g of black chicken bone. The traditional Chinese medicine clysis fluid has the effects of activating blood to dissipate stasis, relieving swelling and pain, eliminating cold to stop pain, clearing damp and promoting diuresis and the like, is capable of effectively covering the shortage that the conventional treatment by use of single western medicine is high in side effect and fails in correcting the yang deficiency-induced cold symptom, and is short in course of treatment and low in side effect.