Application of extractive of ginkgo leaf in preparing medication for treating chronic insufficiency of supplying blood for brain

A technology of cerebral insufficiency and extract, which is applied in the field of medicine, can solve the problems of no focal neurological signs in the brain and long-term efficacy that needs further research.

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0056] At present, the drugs used clinically to treat CCCI include: THA...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Get 5000g of ginkgo biloba powder in 60% ethanol solution at 60-70°C temperature, warm soak for 3 hours, filter, add 7 times the amount of 60% ethanol solution, and warm soak for 2 hours at 60-70°C temperature, Filtrate, combine the filtrates, recover ethanol, concentrate to one-third of the original volume, add water to dilute to twice the original volume, stand for 24 hours, filter, the filtrate is adsorbed by the macroporous adsorption resin, and rinsed with distilled water until the effluent is clear , using 80% ethanol solution as a solvent, eluting, collecting the eluate, recovering ethanol, drying to dryness under reduced pressure, and refining to obtain Ginkgo biloba extract powder. The above extract is mixed with appropriate auxiliary materials to prepare capsules.

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PUM

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Abstract

An application of the gingko leaf's extract (pueraria flavone) in preparing the medicine for treating chronic cerebral ischemia is disclosed. A process for preparing said pueraria flavone is also disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of ginkgo leaf extract in the preparation of medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have been divergent for a long ...

Claims

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Application Information

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IPC IPC(8): A61K36/16A61P9/10
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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