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372results about How to "Clear curative effect" patented technology

Preparation method for efficiently extracting separating high-purity flavone components from ginkgo leaf

InactiveCN103110670AIncrease contentThe ingredients and content are clearNervous disorderGinkgophyta medical ingredientsChemistryKaempferol-3-O-rutinoside
The invention provides a preparation method for efficiently extracting separating high-purity flavone components from ginkgo leaf. The main components are kaempferol-3-O-2'', 6''-dirhamnosylglucoside, rutin, quercetin glucosyl rhamnoside, kaempferol-3-O-rutinoside, isorhamnetin-3-O-rutinoside, quercetin p-coumaroyl glucose rhamnoside and kaempferol p-oumaroyl glucose rhamnoside. The preparation method comprises the following steps: pulverizing the medicinal material ginkgo leaf, adding an alcohol water solution to carry out extraction, concentrating, carrying out nonpolar macroporous adsorbent resin column chromatography on the filtrate, carrying out two-dimensional separation with a novel silica gel substrate bonded material, eluting with a methanol solution, collecting the eluate, concentrating, and drying to obtain the gingko flavone components. The invention enhances the target component content, and obtains the flavone components with definite content. The extraction and separation process has the advantages of high repetitiveness and favorable operability, and is suitable for large-scale preparation of flavone components by separation from ginkgo leaf. The flavone components can be used as a raw material for Shuxuening injections.
Owner:北京华润高科天然药物有限公司

Method for preparing kaempferol-3-O-2'',6''-dirhamnosylglucoside

The invention provides a method for preparing kaempferol-3-O-2'',6''-dirhamnosylglucoside, which comprises the following steps: by using a two-dimensional liquid phase chromatography-mass spectroscopy combination technology and taking methanol-water or acetonitrile-water as a mobile phase and a reversed phase C18 chromatographic column as a one-dimensional preparative chromatographic column, performing component cutting on a ginkgo leaf extract, and collecting a target component which is a kaempferol-3-O-2'',6''-dirhamnosylglucoside crude product; and by taking a reversed phase C18 chromatographic column as a two-dimensional preparative chromatographic column, under the guidance of selective ion peaks of mass spectroscopy, performing component cutting on the kaempferol-3-O-2'',6''-dirhamnosylglucoside crude product, collecting, and concentrating through rotary evaporation to obtain the high-purity kaempferol-3-O-2'',6''-dirhamnosylglucoside, wherein the purity can be up to 70% or above. According to the invention, the preparation process is high in repetitiveness and favorable in operability; and meanwhile, ginkgo leaves are abundant in resources and easy to acquire. Thus, the invention meets the requirements for large-scale production and can be used for the preparation of raw materials for a Shuxuening injection.
Owner:北京华润高科天然药物有限公司

Enzyme compound having bowel relaxing effect, enzyme effervescence granules and preparation method

The invention relates to an enzyme compound having a bowel relaxing effect. The enzyme compound is prepared from, by weight, 1-15 parts of probiotics, 10-120 parts of plant enzyme stock solution and 10-80 parts of traditional Chinese medicine extract, the enzyme compound is prepared by conducting a sterilization process on the traditional Chinese medicine extract, then mixing the extract with the plant enzyme stock solution and inoculating the probiotic florae for airtight fermentation. The traditional Chinese medicine extract is prepared from, by weight, 2-10 parts of sea-buckthorn, 2-10 parts of dahurian rose fruits, 1-8 parts of yam, 2-10 parts of lithospermum erythrorhizon, 2-8 parts of scorched hawthorn fruits, 1-8 parts of tangerine seeds, 0.5-6 parts of grapefruit flowers, 0.5-6 parts of silene aprica, 0.5-6 parts of jujubes and 0.5-5 parts of dried tangerine or orange peels. The enzyme compound enables the probiotics and functional oligosaccharides to be used in a combined mode, the traditional Chinese medicine ingredient is added, the bowel relaxing effect is achieved, and the enzyme compound is suitable for populations who cannot perform blood circulation and hematogenesis due to qi deficiency and accordingly suffer from intestinal moisture loss and constipation.
Owner:FOSHAN LANGDA INFORMATION TECH

Method for preparing high-purity rutin via two-dimensional liquid chromatography-mass spectrometry combined technology

The invention relates to the technical field of medicines, and discloses a method for preparing high-purity rutin via a two-dimensional liquid chromatography-mass spectrometry combined technology. The method comprises the following steps of: adopting the two-dimensional liquid chromatography-mass spectrometry combined technology, taking methanol-water or acetonitrile-water as a mobile phase, using a reversed chromatographic column as the first dimension for preparing a chromatographic column, performing component cutting on a ginkgo leaf extract, and collecting a target component, namely, a rutin crude product; and using the reversed chromatographic column as the second dimension for preparing a chromatographic column, performing component cutting on the rutin crude product under the guide of a mass spectrometry selected ion peak, collecting, rotationally evaporating and concentrating, and then obtaining the high-purity rutin having a purity which can achieve more than 80%. In the method disclosed by the invention, heating is not needed, so that the doping of a hydrolysate is avoided; the preparation is simple in process, high in repeatability, and good in operability; simultaneously, ginkgo leaves are abundant in resource and easy to obtain, thus reducing the cost; and the method is suitable for large-scale production.
Owner:北京华润高科天然药物有限公司

Enzyme composition and effervescent tablet with efficacy of strengthening kidney and tonifying Yang and preparation method

The invention relates to an enzyme composition with the efficacy of strengthening kidney and tonifying Yang. The enzyme composition is prepared from the following components: 1 to 15 weight parts of probiotics, 10 to 120 weight parts of enzyme combination stoste and 10 to 80 weight parts of traditional Chinese medicinal extract; the enzyme composition is formed by treating the traditional Chinese medicinal extract by a sterilization process, then mixing the treated traditional Chinese medicinal extract with the enzyme combination stoste, inoculating a probiotic group and performing airtight fermentation. The traditional Chinese medicinal extract is prepared by extracting the following crude drugs in parts by weight: 2 to 10 parts of rhizoma dioscoreae, 2 to 10 parts of sea cucumber, 1 to 8 parts of morchella, 2 to 10 parts of rhizoma imperatae, 2 to 8 parts of chenopodium quinoa, 1 to 8 parts of root or fruit of fourpetal rose, 0.5 to 6 parts of sea horse, 0.5 to 6 parts of rhizoma curculiginis, 0.2 to 3 parts of sunflower stem pith, 0.5 to 6 parts of fructus jujubae and 0.5 to 5 parts of radix notoginseng. According to the enzyme composition, the probiotics and functional oligosaccharide are combined for use, and traditional Chinese medicinal components are added; the enzyme composition has the efficacy of strengthening kidney and tonifying Yang, and benefiting essence and tonifying Qi.
Owner:FOSHAN LANGDA INFORMATION TECH

Medicine for treating dry eye syndromes

The invention relates to a medicine for treating dry eye syndromes. The medicine for treating dry eye syndromes comprises the following components in parts by weight: 5-10 parts of radix scrophulariae, 10-20 parts of dried ginger, 20-30 parts of dogwood, 10-20 parts of platycodon grandiflorum, 15-25 parts of angelica dahurica, 5-15 parts of inula flower, 10-30 parts of cowherb seed, 1-15 parts of motherwort fruit, 10-20 parts of radix sileris, 15-30 parts of capillary artemisia, 20-30 parts of myrobalan, 1-20 parts of fenugreek, 1-20 parts of celandine, 10-25 parts of rhizoma imperatae, 10-30 parts of cocklebur fruit, 1-20 parts of emblic leafflower fruit, 15-20 parts of kamuning, 10-20 parts of semen pharbitidis, 15-20 parts of lychee seed, 15-30 parts of glabrous sarcandra herb, 10-20 parts of clinopodium polycephalum, 10-25 parts of folium sennae, 5-15 parts of aleppo avens, 1-20 parts of uniflower swisscentaury root, 15-25 parts of folium rhododendri daurici, 15-25 parts of potentilla discolor, 10-20 parts of calyx seu fructus physalis, 15-25 parts of white mulberry root-bark, 20-30 parts of lindley eupatorium, 1-20 parts of gorgon euryale seed and 10-25 parts of Chinese azalea flower. All the components of the medicine for treating dry eye syndromes are natural materials, so that the medicine for treating the dry eye syndromes has good safety and clear curative effect and is suitable for large-scale application in clinic.
Owner:顾克斌

External traditional Chinese medicine for treating diabetic foot and preparation method thereof

The invention provides an external traditional Chinese medicine for treating diabetic foot. The external traditional Chinese medicine comprises rhizoma coptidis, cortex phellodendri, radix angelicae, licorice, Chinese angelica, sangusis draconis, calomel, Chinese wax, lithospermum, radix astragali, earthworm, rhizoma ligustici wallichii and achyranthes bidentata. A preparation method of the external traditional Chinese medicine comprises the following steps: selecting and cleaning the traditional Chinese medicines, and beating the traditional Chinese medicines into crude powder; uniformly mixing, and grinding the mixture into raw material fine powder; boiling rosin, pouring the boiled rosin into a container, cooling and knocking so as to obtain small blocks; boiling vaseline by using medium heat into a liquid, adding small rosin blocks, beewax, honey and sesame oil to the liquid vaseline, and boiling the mixture into oil velvet; melting the small rosin blocks into a paste, pouring the oil velvet into the paste rosin, and uniformly stirring to obtain pasty plaster; putting the raw material fine powder into the pasty plaster, decocting, and pouring the mixture into cold water, thus obtaining the external traditional Chinese medicine plaster finished product. The external traditional Chinese medicine directly acts on the local lesion of the diabetic foot, has a definite curative effect and an obvious treatment effect and is wide in medicinal herb sources, low in cost and convenient to prepare and use.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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