The invention relates to the technical field of traditional Chinese medicine, in particular to a blood fat-lowering health wine, which is prepared by soaking the following raw materials in 45-65° white wine for 15-30 days: 16-20 parts of kudzu root, 16-20 parts of angelica , 16-20 parts of wolfberry, 15-19 parts of turmeric, 15-19 parts of Eucommia, 15-19 parts of ginseng, 14-18 parts of hawthorn, 14-18 parts of rhodiola, 14-18 parts of green plum, 12-14 parts of fig , 12-14 parts of Cangzhu, 12-14 parts of Polygonum cuspidatum, 10-12 parts of hemp seed, 10-12 parts of lotus leaf, 10-12 parts of barley malt, 8-10 parts of jujube seed, 8-10 parts of Gorgon fruit, 5 parts of poria cocos -7 parts, 5-7 parts of honeysuckle, 3-5 parts of burdock seed, 3-5 parts of Prunella vulgaris, 1-3 parts of dried ginger, 1-3 parts of 菥蓂, 1000-1200 parts of white wine. The blood lipid-lowering health wine of the present invention uses high-grade liquor as a medium to fully analyze the active ingredients in the medicinal materials, which greatly improves the utilization rate of the medicinal materials; the medicinal materials of the present invention are scientifically compatible and have no harm to the digestive system and absorption system of the human body. It has no side effects, promotes the normal metabolism of the human body by replenishing qi and blood, and has the effect of lowering blood lipids at the same time.