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Application of medication composition of containing caltrop in preparing medication for treating chronic insufficiency of supplying blood for brain

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of long-term curative effect needing further study, no focal neurological signs in the brain, etc.

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0056] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. A good short-term clinical effect has been achieved, but the long-term effect needs further study

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] (1) Take each component according to the following weight ratio:

[0099] Chuanxiong 750g

[0100] Pueraria 1125g

[0101] Tribulus terrestris 1125g

[0102] (2) Take Ligusticum chuanxiong coarse powder according to the above weight ratio, heat and reflux extract twice with 60% ethanol aqueous solution, add 10 times of 60% ethanol for the first time, heat and reflux for 2 hours, add 8 times for the second time Measure 60% ethanol, heat to reflux for 1.5 hours, combine the extracts, concentrate, spray dry into fine powder, and set aside.

[0103] (3) Take Pueraria root coarse powder by weight ratio above, heat and reflux extract twice with 70% ethanol aqueous solution, add 10 times of 70% ethanol for the first time, heat and reflux for 2 hours, add 8 times of amount for the second time 70% ethanol, heated to reflux for 1.5 hours, combined extracts, concentrated, spray-dried into fine powder, and set aside.

[0104] (4) Take the Tribulus terrestris powder according to t...

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PUM

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Abstract

An application of the medicinal composition composed of Chuan-xiong rhizome, pueraria root and puncturevine caltrop in preparing the medicine for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Tribulus terrestris in the preparation of a medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arterioscler...

Claims

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Application Information

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IPC IPC(8): A61K36/488A61P9/10
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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