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Application of medication composition of containing white peony root in preparing medication for treating chronic insufficiency of supplying blood for brain

A technology of cerebral insufficiency and composition, applied in the field of medicine, can solve the problems that the long-term efficacy needs further research, and there are no focal neurological signs in the brain.

Inactive Publication Date: 2010-09-29
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0024] 3. No focal neurological signs of the brain;
[0025] 4. CT\MRI without vascular organic brain changes;
[0036] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. Good short-term clinical curative effect has been achieved, but the long-term curative effect needs to be further studied

Method used

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  • Application of medication composition of containing white peony root in preparing medication for treating chronic insufficiency of supplying blood for brain
  • Application of medication composition of containing white peony root in preparing medication for treating chronic insufficiency of supplying blood for brain
  • Application of medication composition of containing white peony root in preparing medication for treating chronic insufficiency of supplying blood for brain

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Take the Radix Paeoniae Alba in the amount of raw materials, add water and decoct 2-4 times, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.20-1.50 (50°C), dry, powder into fine powder, and then add the Ginseng stem and leaf saponins and 20-80 weight units of stevioside fine powder (sweetener) and 1-10 weight units of starch are granulated with 60%-80% ethanol, dried, and packed into capsules (each About 0.25g of medicine is filled in the capsule), and the product is obtained.

Embodiment 2

[0070] Take the Radix Paeoniae Alba in the amount of raw materials, add water and decoct 2-4 times, combine the decoction, filter, concentrate the filtrate under reduced pressure to a relative density of 1.20-1.50 (50°C), dry, powder into fine powder, and then add it to the amount of raw materials in turn Ginseng stem and leaf saponins and 20-60 weight units of stevioside fine powder (sweetener) and 1-10 weight units of starch are granulated with 60%-80% ethanol, dried, and magnesium stearate is added 1-5 weight units, mixed evenly, pressed into tablets (core weight 0.39 / tablet), and then coating the core with sugar (15-20kg of white granulated sugar for each kg of tablet core, 14-20kg of talcum powder, polished) , the product is obtained.

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Abstract

An application of the medicinal composition composed of ginseng and white peony root in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Radix Paeoniae Alba in preparing a medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K36/258A61P9/10
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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