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Application of Chinese medicinal composition in preparing medicament for treating chronic cardiac insufficiency

A technology of cardiac insufficiency and composition, applied in the field of medicine, can solve the problem of prevention and treatment of chronic cardiac insufficiency which has not been reported yet, the application of senile dementia drugs, the preparation of drugs for inhibiting albumin leakage, and the preparation of drugs for inhibiting mast cell degranulation , preparation of drugs for the prevention and treatment of plateau hypoxia, etc.

Inactive Publication Date: 2008-08-13
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent application CN1375316A discloses the composition, preparation method and application of the preparation in angina pectoris of coronary heart disease. Chinese patent applications CN200510013503.3A, CN200510013504.8, CN200510013505.2, CN200510013506.7, and CN200510013507.1 respectively disclose the composition Applications in the preparation of drugs for preventing and treating senile dementia, drugs for inhibiting albumin leakage, drugs for inhibiting mast cell degranulation, drugs for preventing and treating plateau hypoxia, and drugs for treating acute pancreatitis. The role of prevention and treatment of chronic cardiac insufficiency has not been reported

Method used

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  • Application of Chinese medicinal composition in preparing medicament for treating chronic cardiac insufficiency
  • Application of Chinese medicinal composition in preparing medicament for treating chronic cardiac insufficiency
  • Application of Chinese medicinal composition in preparing medicament for treating chronic cardiac insufficiency

Examples

Experimental program
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Effect test

Embodiment 1

[0097] Take astragalus 86.5g, salvia miltiorrhiza 21.3g, notoginseng 3.5g, jiangxiang 20.6g, and auxiliary material polyethylene glycol-600030g. Decoct the crushed salvia miltiorrhiza and Panax notoginseng in water twice, adding 7 times the amount of water each time for 2 hours each time, combining the decoction liquid, filtering, and concentrating the filtrate to 900ml, adding 95% ethanol to make the alcohol concentration reach 70%, let it stand for 12-24 hours, filter, recover ethanol, concentrate into an extract with a relative density of 1.32-1.38 (50-60°C); decoct the pulverized Astragalus membranaceus twice with water, adding 6 Double the amount of water, extract for 2 hours and 1 hour in turn, combine the filtrate, and when concentrated to about 1500ml, add 95% ethanol to make the alcohol concentration 60%, let it stand for 12-24 hours, filter, recover ethanol from the filtrate, and concentrate to about 400ml , add 95% ethanol to make the alcohol concentration 80%, let ...

Embodiment 2

[0099] Take the Danshen Sanqi extract, Radix Astragali extract and polyethylene glycol-6000 of Example 1, dissolve in a water bath, and after homogenization, add balsamic volatile oil, mix well, move to the dropping pill machine, and make 1000 dropping pills .

Embodiment 3

[0101] Get Astragalus 40.6g, Salvia miltiorrhiza 44.8g, Panax notoginseng 11.2g, Jiangxiang 38.6g, adjuvant polyethylene glycol-600030g, make 1000 drop pills by the method of embodiment one and embodiment two.

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Abstract

The invention is related to the use of a Chinese medicine composition serving for preparing drug for curing chronic cardiac insufficiency. The composition is formed of the following raw materials by weight: 22.2% to 66.8% of astragalus, 11.6% to 33.4% of salvia, 2.5% to 13.5% of panax notoginseng, 14.5% to 44.3% of lignum dalbergiae odoriferae.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Qishen Yiqi dripping pills in the preparation of medicines for preventing and treating chronic heart insufficiency. Background technique [0002] Cardiac insufficiency, also known as congestive heart failure (referred to as heart failure or heart failure), refers to the reduction of left ventricular blood output due to primary heart damage or long-term pressure or volume overload of the ventricle under the condition of normal venous return. It is a clinical syndrome mainly characterized by hypoperfusion of tissue blood and blood stasis in pulmonary circulation and (or) systemic circulation, manifested as palpitations, shortness of breath, dyspnea, limb edema, liver swelling Pain etc. Chronic cardiac insufficiency is the final destination of almost all patients with organic heart disease. The clinical incidence of this disease is high, and it is one of the m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P9/04
Inventor 吴迺峰
Owner TIANJIN TASLY PHARMA CO LTD
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