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Use of medicinal composition containing red paeony root for preparing medicinefor treating chronic blood shortage to brain

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of lack of focal neurological signs in the brain and the need for further research on long-term efficacy

Inactive Publication Date: 2007-01-10
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0056] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. A good short-term clinical effect has been achieved, but the long-term effect needs further study

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] Take medicinal materials according to the following weight: 12g ginseng, 11g red peony, 3g centipede, 15g scorpion, 24g leech powder, 15g ground beetle, 15g cicada slough, 3g borneol;

[0090] The centipede, scorpion, ground beetle, borneol, etc. in the above medicinal materials are crushed and used for later use. Take the medicinal materials according to the above ratio, add water to extract 3 times, each time for 1 hour, combine the extracts, concentrate appropriately, add 2 times the amount of ethanol, and let stand Precipitate for 24 hours, take the supernatant and concentrate it into an extract, the relative density is 1.3-1.4, and the yield of the extract is 10%, and the clear extract is taken and spray-dried into a powder.

[0091] Pass the above powder, lactose, pregelatinized starch, croscarmellose sodium, and crushed centipede, scorpion, and ground beetle through a 65-mesh sieve for later use, and mix them with other auxiliary materials in an equal-volume incre...

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PUM

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Abstract

The present invention relates to a medicine composition and its application in preparation of medicine for curing chronic cerebral ischemia. Said medicine composition includes 8 Chinese medicinal materials of 10-20 portions of ginseng, 5-15 portions of red peony root, 6-15 portions of centipede, 10-20 portions of scorpion, 20-30 portions of leech, 10-20 portions of wingless cockroach, 10-20 portions of cicada molting and 2-10 portions of borneol.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Radix Paeoniae Rubra in the preparation of a medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arterioscle...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P9/10A61K35/64A61K35/62A61K31/045A61K35/646A61K35/648
Inventor 郑永锋范立君
Owner TIANJIN TASLY PHARMA CO LTD
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