Application of medication composition of containing ligusticum in preparing medicine for treating chronic cerebral circulation insufficin

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of long-term curative effect needing further study, no focal neurological signs in the brain, etc.

Inactive Publication Date: 2009-12-02
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0035] 3. No focal neurological signs of the brain
[0046] 3. No focal neurological signs of the brain;
[0047] 4. CT\MRI without vascular organic brain changes;
[0061] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. Good short-term clinical curative effect has been achieved, but the long-term curative effect needs to be further studied

Method used

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  • Application of medication composition of containing ligusticum in preparing medicine for treating chronic cerebral circulation insufficin
  • Application of medication composition of containing ligusticum in preparing medicine for treating chronic cerebral circulation insufficin

Examples

Experimental program
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Embodiment 1

[0094] Take medicinal materials according to the following weights: 60g Chuanxiong, 40g Ligusticum, 60g Asarum, 40g Angelica, 60g Salvia, 40g Pueraria, 60g Gastrodia, 20g buffalo horn powder;

[0095] Remove the buffalo horn powder, take the medicinal materials according to the above ratio, add water to extract 3 times, 1 hour each time, combine the extracts, concentrate appropriately, add 2 times the amount of ethanol, let stand for 24 hours to precipitate, take the supernatant and concentrate to form an extract, The relative density is 1.3-1.4, and the paste yield is 10%. Take the clear paste and spray dry it into powder.

[0096] Pass the above powder, buffalo horn powder, lactose, pregelatinized starch, and croscarmellose sodium through a 65-mesh sieve for later use, mix them with other auxiliary materials evenly according to the equal amount incremental method, and pass through a 65-mesh sieve for 3 times; Angle, less than 30°; measure the content, set the amount; put the...

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Abstract

An application of the medicinal composition composed of 8 Chinese-medicinal materials including Chuan-xiong rhizome, red sage root, gastrodia tuber, pueraria root, etc in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Ligusticum edulis in the preparation of medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have been divergent for a long...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61K36/53A61K36/48A61K36/264A61K36/236A61K36/232A61K35/32A61P9/10A61P9/02A61P25/28
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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