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Application of medication composition of containing giant typhonium tuber in preparing medicine for treating insufficiency of blood supply for brain

A technology of cerebral insufficiency and composition, applied in the field of medicine, can solve the problems that the long-term efficacy needs further research, and there are no focal neurological signs in the brain.

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0055] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. Good short-term clinical curative effect has been achieved, but the long-term curative effect needs to be further studied

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Take the medicinal materials according to the following weights: 40g chuanxiong, 30g salvia, 20g turmeric, 30g white aconite, 15g bezoar, 20g gastrodia, 30g chrysanthemum, 10g white peony, 30g asarum, 10g dahurica, 10g borneol;

[0087] Remove the borneol and bezoar, take the medicinal materials according to the above ratio, add water and extract 3 times, 1 hour each time, combine the extracts, concentrate appropriately, add 2 times the amount of ethanol, let stand for 24 hours for precipitation, take the supernatant and concentrate it into an extract. The relative density is 1.3-1.4, and the cream output rate is 10%. The clear cream is taken out and spray-dried into a powder.

[0088] Pass the above-mentioned powder, bezoar, borneol, lactose, pregelatinized starch, and croscarmellose sodium through a 65-mesh sieve separately for use, and mix them with other auxiliary materials according to the same amount of addition method, and pass through the 65-mesh sieve 3 times; Angl...

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PUM

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Abstract

An application of the medicinal composition composed of 11 Chinese-medicinal materials including Chuan-xiong rhizome, red sage root, gastrodia tuber, borneol, etc in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

Technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition containing Baifengzi in preparing a medicine for treating chronic cerebral insufficiency. Background technique [0002] Origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to a state where the blood supply to the whole brain is reduced (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed in the first 10 years abroad. In clinical practice, there are often elderly or pre-elder patients who repeatedly complain of conscious symptoms such as heavy head and dizziness. Except for fundus arteriosclerosis, there are neither focal signs of nerve damage nor abnormal brain CT. These patients are often diagnosed as "brain Arteriosclerosis". As we all know, the concept and clinical diagnostic criteria of cereb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/10A61P9/02A61P25/00A61K35/413A61K31/045
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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