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Application of medication composition of containing gastrodia tuber in preparing medicine for treating insufficiency of blood supply for brain

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of lack of focal neurological signs in the brain and the need for further research on long-term efficacy

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0033] 3. No focal neurological signs of the brain
[0043] 3. No focal neurological signs of the brain;
[0044] 4. CT\MRI without vascular organic brain changes;
[0056] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. A good short-term clinical effect has been achieved, but the long-term effect needs further study

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] Choose medicinal materials according to the following prescription, Chuanxiong 100g, Gastrodia elata 25g;

[0089] Dry it, crush it, mix it, and then use 90% ethanol to reflux extract twice, each time for 3 hours, combine the extracts, filter, and concentrate the filtrate to a clear paste with a relative density of 1.27 (55-65°C); decoct the dregs with water Boil, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.27 (55-65°C), combine with the above clear paste, and spray dry it into a powder.

[0090] Pass the above-mentioned powder, lactose, pregelatinized starch, and croscarmellose sodium through a 65-mesh sieve for later use, mix them with other auxiliary materials according to the equal-volume incremental method, and pass through a 65-mesh sieve 3 times; measure the angle of repose, and it is less than 30 °; measure the content, set the amount; pack the powder into No. 3 capsules.

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PUM

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Abstract

An application of the medicinal composition composed of Chuan-xiong rhizome and gastrodia tuber in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Gastrodia elata in the preparation of medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis hav...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/02A61P9/10
Inventor 范立君李永强
Owner TIANJIN TASLY PHARMA CO LTD
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