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Application of medication composition of containing giant typhonium tuber in preparing medicine for treating insufficiency of blood supply for brain

A technology of insufficient cerebral blood supply and composition, applied in the field of medicine, can solve the problems of lack of focal neurological signs in the brain and the need for further research on long-term efficacy

Inactive Publication Date: 2009-10-14
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0036] 3. No focal neurological signs of the brain
[0047] 3. No focal neurological signs of the brain;
[0048] 4. CT\MRI without vascular organic brain changes;
[0062] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. A good short-term clinical effect has been achieved, but the long-term effect needs further study

Method used

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  • Application of medication composition of containing giant typhonium tuber in preparing medicine for treating insufficiency of blood supply for brain
  • Application of medication composition of containing giant typhonium tuber in preparing medicine for treating insufficiency of blood supply for brain

Examples

Experimental program
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Effect test

Embodiment 1

[0095] Take medicinal materials according to the following weights: 40g Chuanxiong, 30g Salvia, 20g Curcuma, 30g Baifuzi, 15g Bezoar, 20g Gastrodia elata, 30g Chrysanthemum, 10g Paeoniae Alba, 30g Asarum, 10g Angelica dahurica, 10g Borneol;

[0096] Remove the borneol and bezoar, take the medicinal materials according to the above ratio, add water to extract 3 times, 1 hour each time, combine the extracts, concentrate appropriately, add 2 times the amount of ethanol, let stand for 24 hours to precipitate, take the supernatant and concentrate it into an extract, The relative density is 1.3-1.4, and the paste yield is 10%. Take the clear paste and spray dry it into powder.

[0097] Pass the above-mentioned powder, bezoar, borneol, lactose, pregelatinized starch, and croscarmellose sodium through a 65-mesh sieve for later use, mix them with other auxiliary materials according to the method of equal addition, and pass through a 65-mesh sieve for 3 times; Angle, less than 30°; meas...

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PUM

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Abstract

An application of the medicinal composition composed of 11 Chinese-medicinal materials including Chuan-xiong rhizome, red sage root, gastrodia tuber, borneol, etc in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing Radix Aconiti Radix in preparing medicine for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have been divergent for a long time. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K36/8988A61K36/888A61K36/71A61K36/53A61K36/28A61K36/264A61K36/236A61K36/232A61K35/413A61K31/045A61P9/10A61P9/02A61P25/00
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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