18 results about "Anemarrhena asphodeloides" patented technology

This invention discloses a method for preparing a heat-clearing and detoxifying oral liquid. Honeysuckle and Scutellaria baicalensis are pulverized and sieved, then enzymatically hydrolyzed with water, ultrasonically extracted, and filtered to obtain extract A. Scrophularia ningpoensis, Rehmannia glutinosa, Forsythia suspensa, Gardenia jasminoides, Viola yedoensis, Gentiana scabra, Isatis indigotica, Anemarrhena asphodeloides, and Ophiopogon japonicus are warm-soaked in water and flash-extracted, then filtered to obtain extract B. Gypsum is crushed, decocted with water, and filtered to obtain extract C. The extracts are combined, concentrated, and sequentially clarified using a flocculant, followed by inorganic ceramic membrane microfiltration and organic ultrafiltration. The clarified liquid is then concentrated, flavoring agents and preservatives are added, the pH is adjusted, the volume is adjusted, filtered, filled, and sterilized to obtain the finished product. This invention utilizes a composite clarification process—low-temperature ultrasonic-enzymatic extraction of honeysuckle and Scutellaria baicalensis, clarification using a flocculant, inorganic ceramic membrane microfiltration, and organic ultrafiltration—to improve the extraction rate of effective components, effectively remove large molecular impurities such as tannins, proteins, and pectin, and significantly improve the clarity and stability of the product.

This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for treating intestinal injury. The traditional Chinese medicine composition comprises: 50-150 parts of ginseng, 60-180 parts of polygonatum, 40-90 parts of atractylodes, 30-58 parts of sophora flavescens, 60-180 parts of ophiopogon japonicus, 60-110 parts of rehmannia glutinosa, 40-90 parts of polygonum multiflorum, 60-180 parts of cornus officinalis, 40-90 parts of poria cocos, 35-58 parts of eupatorium fortunei, 35-58 parts of coptis chinensis, 35-90 parts of anemarrhena asphodeloides, 35-58 parts of epimedium, 40-110 parts of salvia miltiorrhiza, 60-180 parts of kudzu root, 80-140 parts of litchi seed, and 40-90 parts of lycium chinense root bark. The above-mentioned traditional Chinese medicine composition can inhibit the expression of TNF, AGE-RAGE, TLR and IL-17 and the infiltration of macrophages. It also helps to regulate the proliferation and differentiation of intestinal cells, restore beneficial bacteria in the intestine, and significantly improve the barrier function of the intestine, thereby effectively improving the damaged intestinal function.

The application provides a traditional Chinese medicine extract for treating pancreatic cancer and a preparation method and application thereof, and belongs to the technical field of biological medicine. The traditional Chinese medicine extract comprises the following steps: obtaining white peony root powder by stir-frying, obtaining atractylodes powder by stir-frying atractylodes with wheat bran, obtaining radix astragali powder by wine-frying, then mixing the white peony root powder, anemarrhena asphodeloides powder, codonopsis powder, atractylodes powder, radix astragali powder, citrus peel powder, magnolia officinalis powder, gigeriae gall powder, ginger powder, chuanxiong powder, cassia twig powder, safflower powder and peach kernel powder to obtain mixed powder, mixing the mixed powder with an ethanol aqueous solution, refluxing extraction, filtering, collecting the extract, concentrating, drying, and obtaining the traditional Chinese medicine extract; the traditional Chinese medicine extract can significantly inhibit the activity, migration ability of pancreatic cancer cells and the growth of pancreatic cancer, and research shows that the tumor killing effect of the traditional Chinese medicine extract with a high dose is better than that of a positive drug. The preparation method is simple and easy to implement, and is suitable for industrial production.

This invention discloses a traditional Chinese medicine composition for the prevention and / or treatment of herpes and / or its complications. By weight, the composition comprises: 8-14 parts of Sophora flavescens, 5-11 parts of Bistorta officinalis, 9-15 parts of Rheum palmatum, 0.5-6 parts of Coptis chinensis, 1-7 parts of Forsythia suspensa, 1-7 parts of Taraxacum mongolicum, 1-7 parts of Viola yedoensis, 1-7 parts of Paeonia lactiflora, 1-7 parts of Paeonia suffruticosa, 1-7 parts of Gardenia jasminoides, 3-9 parts of Rehmannia glutinosa, 1-7 parts of Chrysanthemum indicum, 1-7 parts of Lonicera japonica, 1-7 parts of Atractylodes lancea, 0.5-6 parts of Phellodendron chinense, 0.5-1.5 parts of Cicadae periostracum, 2-8 parts of Smilax glabra, 1-7 parts of Anemarrhena asphodeloides, 1-7 parts of Ophiopogon japonicus, 0.5-6 parts of Alisma plantago-aquatica, and 1-7 parts of Gypsum fibrosum. The complications are pain and / or inflammation. This traditional Chinese medicine composition is safe, effective, and has a simple and efficient preparation method with controllable quality. It also exhibits significant analgesic and anti-inflammatory effects and can treat shingles and its sequelae.

The application discloses a use of taibai araloside in treating hypoxic pulmonary arterial hypertension. In the use of hypoxia to induce pulmonary arterial hypertension, it is found that the taibai araloside can reduce right ventricular pressure and right heart hypertrophy index, and inhibit pulmonary arterial remodeling; the taibai araloside reduces the expression and activity of ACE in the lung in a concentration-dependent manner, and corrects the disorder of the RAS system in the lung caused by hypoxic pulmonary arterial hypertension. Moreover, a monomer component of the taibai araloside, anemarrhena asphodeloides glycoside and chizhenshan saponin IVa, has a stable combination with ACE. The results show that the taibai araloside has the potential to be developed into a drug for preventing and treating hypoxic pulmonary arterial hypertension in the clinic, and also provides a prevention and treatment strategy for interstitial lung disease, chronic obstructive pulmonary disease, sleep apnea syndrome, chronic high altitude disease and neonatal respiratory disease.

The application relates to a traditional Chinese medicine composition for nourishing kidney and relieving depression as well as a preparation method and application thereof. The application relates to a traditional Chinese medicine composition and a preparation method and application thereof. In order to solve the problems that long-term hormone replacement therapy not only has more adverse reactions, but also has potential risks of causing endometrial lesions, thrombosis and tumors, the traditional Chinese medicine composition comprises radix codonopsis, radix ophiopogonis, taxilli herba, radix dioscoreae, ligustri fructus, anemarrhena asphodeloides, herba ecliptae, radix paeoniae alba, radix bupleuri, pericarpium citri reticulatae, fritillaria, poria cocos, semen ziziphi spinosae and schisandra chinensis. The traditional Chinese medicine composition is applied to preparation of a medicine for preventing and / or treating perimenopausal syndrome and premature ovarian failure. The application belongs to the technical field of medicines.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for treating hyperuricemia complicated with metabolic syndrome, its preparation method, and its application. The traditional Chinese medicine composition comprises the following components in parts by weight: Codonopsis pilosula 3-6 parts, Astragalus membranaceus 12-18 parts, Bupleurum chinense 1-5 parts, Citrus reticulata peel 1-5 parts, Citrus aurantium peel 3-6 parts, Scutellaria baicalensis 1-5 parts, Nelumbo nucifera leaf 3-6 parts, Crataegus pinnatifida 3-6 parts, Anemarrhena asphodeloides 12-18 parts, Coptis chinensis 1-3 parts, Polygonatum sibiricum 3-6 parts, Pueraria lobata 28-35 parts, Schisandra chinensis 1-5 parts, Smilax glabra 28-35 parts, Cimicifuga foetida 1-5 parts, processed chicken gizzard lining 5-10 parts, Lycopus lucidus 3-6 parts, Atractylodes lancea 3-6 parts, Phellodendron chinense 3-6 parts, and Liquidambar formosana 3-6 parts. The traditional Chinese medicine composition of this invention follows the theory of traditional Chinese medicine compatibility, and synergistically achieves the effects of strengthening the spleen and soothing the liver, resolving phlegm and drying dampness, clearing heat and removing blood stasis. By effectively reducing the levels of blood uric acid, triglycerides, systolic blood pressure and diastolic blood pressure, and regulating key indicators such as high-density lipoprotein, it significantly improves the clinical symptoms of patients with hyperuricemia and metabolic syndrome. Moreover, it has good safety in clinical application and no obvious adverse reactions.

This invention relates to the fields of pharmaceuticals and health foods, and particularly to a polysaccharide from *Anemarrhena asphodeloides* AAP1-1-A, its preparation method, and its applications. The invention involves mixing *Anemarrhena asphodeloides* rhizome powder with water for extraction, obtaining an extract; concentrating the extract, mixing the concentrate with ethanol, and precipitating the concentrate to obtain crude polysaccharide; subjecting the crude polysaccharide to protein removal, dialysis, and freeze-drying to obtain *Anemarrhena asphodeloides* polysaccharide AA1; and then performing ion-exchange column chromatography and molecular sieve gel column chromatography on *Anemarrhena asphodeloides* polysaccharide AA1 to obtain *Anemarrhena asphodeloides* polysaccharide AAP1-1-A. The molecular weight of *Anemarrhena asphodeloides* polysaccharide AAP1-1-A is 1000~100000 Da. The preparation method is simple, the reaction conditions are mild, and it can be produced on a large scale. Furthermore, the *Anemarrhena asphodeloides* polysaccharide AAP1-1-A obtained by this invention lays the foundation for the development of *Anemarrhena asphodeloides* polysaccharide as an anti-Parkinson's disease active drug, health food, and functional food, as well as for its quality control and in-depth research on its structure-activity relationship and mechanism of action.

The invention provides a traditional Chinese medicine composition for treating diabetic nephropathy as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 40 to 50 parts of rhizoma coptidis, 40 to 50 parts of radix astragali seu hedysari, 25 to 35 parts of radix paeoniae rubra, 25 to 35 parts of radix salviae miltiorrhizae, 3 to 9 parts of scalded leech, 1 to 5 parts of wine-treated radix et rhizoma rhei, 110 to 130 parts of fried fructus rosae laevigatae, 110 to 130 parts of fried semen euryales, 25 to 35 parts of rhizoma anemarrhenae and 25 to 35 parts of radix trichosanthis. Animal experiments prove that the traditional Chinese medicine composition reduces fasting blood-glucose and urine trace protein content of rats with diabetic nephropathy. Clinical cases prove that the traditional Chinese medicine composition improves various symptoms of the diabetic nephropathy and has a remarkable curative effect on treating the diabetic nephropathy.

This invention relates to a traditional Chinese medicine composition for delaying the progression of kidney deficiency and blood stasis syndrome in diabetic nephropathy, its application, and preparation method. The composition is made from Astragalus membranaceus, Salvia miltiorrhiza, Paeonia lactiflora, Anemarrhena asphodeloides, Phellodendron chinense, Cistanche deserticola, Scutellaria baicalensis, Euonymus alatus, Schisandra chinensis, raw oyster shell, Plantago asiatica, and Artemisia annua. It has the effects of nourishing the kidneys, clearing heat, eliminating toxins, and unblocking the meridians. This traditional Chinese medicine composition can effectively delay the decline in renal function in patients with massive proteinuria during the diabetic nephropathy stage, improve the clinical symptoms of patients with kidney deficiency and blood stasis syndrome, and improve their quality of life. Simultaneously, it has a low risk of hyperkalemia and gastrointestinal bleeding, and no significant damage to liver function has been observed, indicating high safety.

This invention discloses a lung-nourishing Solomon's Seal Ointment, its preparation method, and its application, relating to the field of traditional Chinese medicine technology. The herbal composition comprises three herbs: Herb A, Herb B, and Herb C. Herb A includes Solomon's Seal, Lycium barbarum, Chrysanthemum indicum, Mulberry fruit, White peony root, Rehmannia glutinosa, Raw Chinese yam, Ziziphus jujuba peel, Moutan bark, and Poria cocos. Herb B includes Achyranthes bidentata, Polygonatum sibiricum (processed with wine), Ophiopogon japonicus, Adenophora stricta, Tangerine peel, Prepared licorice root, Astragalus membranaceus, and Anemarrhena asphodeloides. The lung-nourishing Solomon's Seal Ointment is prepared by combining Herbs A and B in the herbal composition, decocting them in water, filtering the filtrate, concentrating the liquid, adding Herb C to dissolve, and then simmering over low heat to form an ointment. This technical solution is applied to the treatment of chronic obstructive pulmonary disease (COPD), forming a multi-target, holistic conditioning system. It provides crucial synergistic value to Western medicine's strategy of simply controlling symptoms in improving chronic COPD symptoms and enhancing quality of life, thereby improving the quality of life for COPD patients.

This invention discloses the application of a traditional Chinese medicine composition in the preparation of a drug for treating sarcopenia, wherein the traditional Chinese medicine composition consists of Astragalus membranaceus and Anemarrhena asphodeloides. The study found that the combination of Astragalus membranaceus and Anemarrhena asphodeloides can significantly improve the differentiation function of C2C12 myoblasts induced by high glucose and inhibit lipid deposition, and improve skeletal muscle mass, muscle strength, and motor function in a streptozotocin-induced C57BL / 6 diabetic sarcopenia mouse model. In vitro and in vivo experiments have confirmed that this drug has significant effects in improving muscle atrophy, enhancing motor function, and restoring muscle strength; it can effectively increase the cross-sectional area of ​​muscle fibers, promote myotube fusion, and accelerate damage repair, showing a clear potential to inhibit diabetic muscle atrophy. This provides an effective traditional Chinese medicine compound intervention strategy for the clinical treatment of diabetic sarcopenia and has good prospects for development and application.

This invention provides a compound microecological preparation for enhancing the intestinal function of marine fish, its preparation method, and its application, belonging to the technical field of aquatic feed additives. The compound microecological preparation of this invention includes a carrier, traditional Chinese medicine extracts, and a compound bacterial flora; the traditional Chinese medicine extracts consist of seaweed extract, *Anemarrhena asphodeloides* extract, and *Eucommia ulmoides* leaf extract, with their total content accounting for 10-20% of the total weight of the compound microecological preparation; the compound bacterial flora consists of *Rhodopseudomonas palustris*, *Rhodotorula rubra*, and *Clostridium butyricum*, with a total viable count ≥15 billion CFU / g of the compound microecological preparation. This invention, through the scientific combination of traditional Chinese medicine extracts and the compound bacterial flora, effectively solves the intestinal health problems of marine fish, while simultaneously promoting growth and improving meat quality.

This invention discloses a formula for nourishing the kidneys, clearing heat, promoting diuresis, and resolving blood stasis, and its application. The formula comprises the following ingredients in parts by weight: Anemarrhena asphodeloides 7-13 parts, Rehmannia glutinosa 7-13 parts, Trionyx sinensis 12-18 parts, Dianthus superbus 7-13 parts, Dendrobium nobile 7-13 parts, Prunus persica 7-13 parts, Trichosanthes kirilowii 9-15 parts, Coptis chinensis 2-7 parts, Phellodendron chinense 7-13 parts, Cinnamomum cassia 2-7 parts, and Plantago asiatica 7-13 parts. This formula, provided by this invention, not only treats polycystic ovary syndrome but also significantly improves quality of life and has a role in preventing and treating depression. The present invention discloses a kidney-nourishing, heat-clearing, dampness-dispelling, and blood stasis-resolving formula and its application. The formula comprises the following raw materials by weight: 7-13 parts of Anemarrhena asphodeloides, 7-13 parts of Rehmannia glutinosa, 12-18 parts of turtle shell, 7-13 parts of Desmodium styracifolium, 7-13 parts of Dendrobium, 7-13 parts of peach kernel, 9-15 parts of Trichosanthes seed, 2-7 parts of Coptis chinensis, 7-13 parts of Phellodendron amurense, 2-7 parts of cinnamon twig, and 7-13 parts of Plantago major. The kidney-nourishing, heat-clearing, dampness-dispelling, and blood stasis-resolving formula provided by this invention is capable of significantly improving the quality of life and preventing depression while treating polycystic ovary syndrome.

This invention discloses a Qingjin Huatan Decoction and its application in regulating the serum inflammatory factor protein network of patients with AECOPD and phlegm-heat accumulation in the lungs, belonging to the field of biomedical technology. The Qingjin Huatan Decoction of this invention is composed of the following raw materials in parts by weight: Scutellaria baicalensis 10-20 parts, Gardenia jasminoides 6-12 parts, Morus alba root bark 6-12 parts, Trichosanthes kirilowii 10-14 parts, Fritillaria thunbergii 6-12 parts, Ophiopogon japonicus 6-12 parts, Platycodon grandiflorus 10-20 parts, Anemarrhena asphodeloides 6-12 parts, Citrus reticulata peel 10-20 parts, Poria cocos 10-20 parts, and Glycyrrhiza uralensis (processed) 4-8 parts. This formula is consistent with the core pathogenesis of AECOPD and phlegm-heat accumulation in the lungs, with appropriate warming and cooling properties, and a combination of tonifying and purging effects. It can inhibit the proliferation of pathogenic bacteria in the intestines, correct intestinal flora imbalance, achieve intestinal-lung harmony through the intestinal-lung axis, comprehensively improve patients' clinical symptoms, and enhance clinical suitability.

A traditional Chinese medicine composition for improving or treating acute lung injury and an application thereof. The traditional Chinese medicine composition is made of the following traditional Chinese medicine raw materials: Areca catechu 12-24 parts, Magnolia officinalis 6-12 parts, Amomum tsao-ko 3-6 parts, Anemarrhena asphodeloides 6-12 parts, Paeonia lactiflora 6-12 parts, Scutellaria baicalensis 6-12 parts, Glycyrrhiza uralensis 3-6 parts, Rheum officinale 6-12 parts, Forsythia suspensa 8-16 parts, Mentha haplocalyx 3-6 parts, Gardenia jasminoides 3-6 parts, Mirabilite 3-6 parts, and Bambusa 5-10 parts. In a mouse animal model experiment, the traditional Chinese medicine composition described herein not only can alleviate the phenomenon of inflammatory cell infiltration in the bronchoalveolar lavage fluid caused by LPS, reduce the inflammatory response, but also can help to improve the lung tissue pathological injury induced by LPS, maintain the alveolar structure integrity, inhibit pulmonary edema, down-regulate the level of inflammatory factors in the bronchoalveolar lavage fluid, and inhibit the expression of inflammatory factors in the lung tissue, thereby improving or treating acute lung injury caused by LPS.

A traditional Chinese medicine composition for nourishing kidney, clearing heat, removing dampness and removing blood stasis, an extract, a pharmaceutical preparation, a preparation method and an application thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: Anemarrhena asphodeloides 7-13 parts, Rehmannia glutinosa 7-13 parts, Trionyx sinensis 12-18 parts, Viola mandshurica 7-13 parts, Dendrobium 7-13 parts, Semen Pruni 7-13 parts, Semen Cucurbitae 9-15 parts, Coptis deltoidea 2-7 parts, Phellodendron amurense 7-13 parts, Cinnamomum cassia 2-7 parts, Plantago asiatica 7-13 parts, and Glycyrrhiza uralensis 2-12 parts. The traditional Chinese medicine composition can treat polycystic ovary syndrome, and can also significantly improve the quality of life and has the effect of preventing and treating depression.

The present application provides a plant composition for oil control, dandruff removal and nourishment and a hair product thereof, and belongs to the field of medical, dental or cosmetic preparations. The composition is composed of Sophora flavescens, Radix Angelicae Sinensis, Sapindus, Anemarrhena asphodeloides, and optional extracts of Scutellaria baicalensis and Passiflora incarnata, and is prepared by precise processes such as directional extraction of liposoluble alkaloids, directional extraction of water-soluble saponins and gradient solvent extraction. Through multi-target synergistic action, the components can significantly inhibit the proliferation of Malassezia, regulate the secretion of sebaceous glands, and improve the microcirculation of the scalp. The present application has multiple effects of oil control, dandruff removal, itching relief and nourishment, and is mild and non-irritating, and is suitable for various hair washing and care products.