Application of medication composition of containing notoginseng in preparing medicine for treating insufficiency of blood supply for brain

A technology of cerebral insufficiency and composition, applied in the field of medicine, can solve the problems of no focal neurologic signs in the brain, and long-term efficacy needs further research.

Inactive Publication Date: 2010-04-28
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0024] 3. No focal neurological signs of the brain;
[0025] 4. CT\MRI without vascular organic brain changes;
[0036] At present, the drugs used clinically to treat CCCI include: THA: cholinesterase inhibitor, GST-21: central N-choline receptor inhibitor, FK506: immunosuppressant, Nimsuperzine: Cox-2 inhibitor, etc. Good short-term clinical curative effect has been achieved, but the long-term curative effect needs to be further studied

Method used

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  • Application of medication composition of containing notoginseng in preparing medicine for treating insufficiency of blood supply for brain
  • Application of medication composition of containing notoginseng in preparing medicine for treating insufficiency of blood supply for brain
  • Application of medication composition of containing notoginseng in preparing medicine for treating insufficiency of blood supply for brain

Examples

Experimental program
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Effect test

Embodiment 1

[0071] 1. Preparation of Panax notoginseng extract

[0072] Take Panax notoginseng, add 10 times the amount of purified water, boil for 2 hours, take out the liquid medicine, add 6 times the amount of purified water to the dregs, boil for 1.5 hours, take out the liquid medicine, combine the two extracts, and put them in a high-speed tubular centrifuge (2000r / min) centrifuge to remove impurities, concentrate to 1 / 2 volume (density 1.09-1.11), spray-dry (inlet air 175°C, outlet temperature 90°C, wind pressure 0.5Mpa).

[0073] 2. Preparation of Gastrodia elata extract

[0074] Get Gastrodia elata 10Kg, add 80% edible alcohol 8 times amount and reflux extract for 2 hours; Filter, medicine dregs add 80% edible alcohol 6 times amount reflux extract 1.5 hours, filter, merge two filtrates, concentrate under reduced pressure to no alcohol smell (density 1.09-1.11), spray drying (inlet air 175°C, outlet temperature 90°C, wind pressure 0.5Mpa), to obtain.

[0075] 3. Preparation of Ca...

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PUM

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Abstract

An application of the medicinal composition composed of notoginseng and gastrodia tuber in preparing the medicines for treating chronic cerebral ischemia is disclosed.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a medicinal composition containing notoginseng in the preparation of medicines for treating chronic cerebral insufficiency. Background technique [0002] The origin of the concept [0003] Chronic Cerebral Circulation Inefficiency (CCCI) refers to the state of reduced blood supply to the brain at the overall level (less than 40-60ml / 100g brain tissue / minute), rather than focal cerebral ischemia. It is a relatively new disease name proposed by foreign countries in the first 10 years. Clinically, some elderly or pre-senile patients who repeatedly complain of subjective symptoms such as heavy head and dizziness have neither focal signs of nerve damage nor brain CT abnormalities except fundus arteriosclerosis. Arteriosclerosis". It is well known that the concept and clinical diagnostic criteria of cerebral arteriosclerosis have been divergent for a long time...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61K36/258A61P9/10
Inventor 范立君郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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