Non-invasive blood component value measuring instrument and method

a blood component and measurement instrument technology, applied in the field of instruments and methods, can solve the problems of inability to measure items so far by existing measuring methods, difficult to estimate glucose concentration in blood from transmitted light obtained, and no other method availabl

Inactive Publication Date: 2006-03-23
TYT INST OF TECH
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Problems solved by technology

In addition, there is no other method available than the blood examination for measuring blood biochemical constituent.
On the other hand, a non-invasive measurement using near infrared light is collecting attentions for extremely low risk to living bodies and the possibility for measurement of items so far impossible by existing measuring methods.
For this method, however, it is very difficult to estimate glucose concentration in blood from the transmitted light obtained and thus a method to estimate glucose concentration using a multi-regression analysis is also proposed.
However, the absorption band inherent to glucose in the near infrared range overlaps on other constituent absorptio

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  • Non-invasive blood component value measuring instrument and method
  • Non-invasive blood component value measuring instrument and method
  • Non-invasive blood component value measuring instrument and method

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Embodiment Construction

[0023] An embodiment of the present invention will be described below in detail referring to the attached drawings. In the embodiment shown below, the concentration measurement of blood glucose as one of blood constituents will be explained. However, the present invention is also applicable to the concentration measurement of such other materials as glycol-albumin, hemoglobin A1C(HbA1C), cholesterol and so on, which are blood constituents other than blood glucose existing in the arterial blood having light absorption characteristics and scattering as well as reflecting characteristics.

[0024]FIG. 1 is a block diagram showing a non-invasive blood glucose concentration measuring instrument of the present invention.

[0025] As shown in FIG. 1, the light source 11 to emit a light having a near infrared wavelength range of, for example, 800˜2400 nm wavelength has been installed in a non-invasive blood glucose concentration measuring instrument. The light emitted from the light source 11 i...

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Abstract

A non-invasive blood constituents measuring instrument measures blood constituent values including blood glucose concentration in a living body. The instrument is composed of a light source 11 to irradiate a light containing plural wavelengths to a living body 13, a light detector 14 to detect the light transmitted through a living body or reflected thereon, an instantaneous spectrum analyzer 15 to analyze the light transmitted through the living body or reflected thereon at different times, a subtraction processor 18 to generate spectrum subtraction from the spectrum of the light at the different times measured by the spectrum analyzer 15, and a blood glucose concentration predictor 21 into which the output data of the subtraction processor 18 are input and which outputs a blood constituent value.

Description

FIELD OF THE INVENTION [0001] The present invention relates to an instrument and a method for measuring blood biochemical constituent including blood glucose concentration and, more particularly, to a non-invasive blood constituent measuring instrument and a method for measuring blood glucose concentration without sampling blood from a living body. [0002] In the modern era of the expanding aged society as well as the change in life-style, there has been a considerable increase in the number of diabetes which is growing social concern as a representative of lifestyle-related diseases. It is so far a general practice to measure blood glucose concentration by sampling a small amount of blood. However, it is strongly desired to reduce pain and botheration associated with the blood sampling. In addition, there is no other method available than the blood examination for measuring blood biochemical constituent. [0003] On the other hand, a non-invasive measurement using near infrared light ...

Claims

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Application Information

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IPC IPC(8): A61B5/00G01N33/49
CPCA61B5/14532A61B5/14546A61B5/1455G01N2201/129G01N33/491G01N2201/1228G01N2201/1232G01N21/359A61B5/14
Inventor YAMAKOSHI, KEN-ICHI
Owner TYT INST OF TECH
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