Retractable Injection Port

a technology of ophthalmic drugs and injection ports, which is applied in the field of single-use medical devices, can solve the problems of increased risk of post-operative infection, loss of intra-ocular tissue and fluid, and difficulty in adjusting the ophthalmic drug delivery devi

Inactive Publication Date: 2008-11-13
ALCON RES LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008]In one embodiment, consistent with the principles of the present invention, the present invention is a cannula, for delivering a bolus of a pharmaceutically active agent to the posterior chamber of the eye, having an orifice disposed at the distal tip. The cannula is slidably disposed within a hypodermic needle. The sliding action of the cannula within the needle provides a means for trimming a formed bolus of a pharmaceutically active agent from the orifice of the cannula. In addition, the double wall formed by the cannula within the needle provides insulation from the cooler temperatures within the eye to allow for the delivery of a phase transition drug formulation.

Problems solved by technology

Problems would arise with respect to conditions requiring a cannula that cannot utilize a trocar due to cannula length or the injection location.
This procedure introduces significant risks, including but not limited to trauma to the eye at the incision site, increased risk of post-operative infection, and loss of intra ocular tissue and fluid since the eye is a pressurized globe.
In addition, this requirement adds significant time to the overall procedure.
Use of prior art needles for such a treatment would result in a cylindrical or “worm shaped” solid being deposited in the eye.
Of those commercialized, there are none specifically associated with injectors that are designed to deliver melted or phase transition materials.
In addition, none of the commercially available needle styles offer a means to trim the injected bolus from the cannula body.
This may result in the drug being deposited in the sclera when the needle or cannula is removed from the eye.

Method used

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Examples

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Embodiment Construction

[0016]Reference is now made in detail to the exemplary embodiments of the invention, examples of which are illustrated in the accompanying figures. Wherever possible, the same reference numbers are used throughout the figures to refer to the same or like parts.

[0017]FIG. 1 is one view of an ophthalmic medical device including a needle and a cannula according to an embodiment of the present invention. In FIG. 1, medical device 10 includes cannula 12 and needle 14. Cannula 12 includes closed distal tip 16 and orifice 18. Needle 14 includes beveled tip 20.

[0018]Cannula 12 is slidably disposed within needle 14 and may be fluidly connected to any appropriate mechanism for storage and delivery of a pharmaceutically active agent, such as a syringe or IV tube, but is most preferably fluidly coupled to a heated syringe as illustrated in FIG. 4. A pharmaceutically active agent, typically a drug suspended in a phase transition compound, is contained within the storage and delivery mechanism. T...

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Abstract

A cannula, for delivering a bolus of a pharmaceutically active agent to the posterior chamber of the eye, having an orifice disposed at the distal tip. The cannula is slidably disposed within a hypodermic needle. The sliding action of the cannula within the needle provides a means for trimming a formed bolus of a pharmaceutically active agent from the orifice of the cannula. In addition, the double wall formed by the cannula within the needle provides insulation from the cooler temperatures within the eye to allow for the delivery of phase transition substances.

Description

RELATED APPLICATIONS[0001]This application is a continuation-in-part of U.S. patent application Ser. No. 11 / 581,629 filed Oct. 16, 2006, U.S. patent application Ser. No. 11 / 581,630 filed Oct. 16, 2006, and U.S. patent application Ser. No. 11 / 581,591 filed Oct. 16, 2006.FIELD OF THE INVENTION[0002]The present invention relates to a single-use medical device and more particularly to an ophthalmic drug delivery device with a retractable injection port.BACKGROUND OF THE INVENTION[0003]Several diseases and conditions of the posterior segment of the eye threaten vision. Age related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathies (e.g., diabetic retinopathy, vitreoretinopathy), retinitis (e.g., cytomegalovirus (CMV) retinitis), uveitis, macular edema, glaucoma, and neuropathies are several examples.[0004]These, and other diseases, can be treated by injecting a drug into the eye. Such injections are typically manually made using a conventional syringe and need...

Claims

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Application Information

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IPC IPC(8): A61M31/00A61M5/178
CPCA61F9/0017A61M2005/14268A61M5/20A61M5/3129A61M5/31511A61M5/445A61M2205/3368A61M2205/3653A61M2205/50A61M2205/6027A61M2205/8206A61M2210/0612A61M5/1413A61M5/14546A61M5/14566A61M5/14244A61M5/14526A61F9/0008A61M5/178A61M31/00A61M35/003A61M2005/14284A61M2205/52
InventorHICKINGBOTHAM, DYSON W.SANCHEZ, ROBERT J.
OwnerALCON RES LTD