Anti-il-9 antibody formulations and uses thereof
a technology of antibody formulation and anti-il-9, which is applied in the field of anti-il-9 antibody formulations, can solve the problems of lyophilized antibody formulations, high manufacturing cost, and significant waste, and achieves the effects of low to undetectable levels of antibody fragmentation and/or aggregation, low cost of manufacturing, and low loss of biological activities
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[0099]The liquid formulations of the present invention provide a ready-to-use preparation of an antibody (including antibody fragment thereof) that immunospecifically binds to an IL-9 polypeptide for administering to a subject without having to reconstitute the preparation accurate and aseptical techniques, and waiting for a period of time until the solution clarifies before administering the formulation to the subject. In addition, such reconstituted solutions must be used within a certain period, leading to very costly waste. It simplifies the procedure of administering the formulation to a subject for a healthcare professional. Furthermore, due to its high stability during the storage, the formulations of the present invention can contain an antibody (including antibody fragment thereof) that immunospecifically binds to an IL-9 polypeptide at concentrations in the range of about 15 mg / ml to about 300 mg / ml without causing an adverse effect on the biological activities of the anti...
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