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System and Method for Increasing a Target Zone for Electrical Ablation

a target tissue and target area technology, applied in the field of medical treatment devices, can solve the problems of increasing the risk of patients, affecting the accuracy of electrode placement, and prolonging the entire treatment procedur

Inactive Publication Date: 2014-02-13
ANGIODYNAMICS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This approach enables a larger target ablation zone to be achieved with fewer electrodes, reducing procedure time and complexity while maintaining effectiveness, thus improving safety and efficiency.

Problems solved by technology

This makes accurately placing the electrodes much more difficult as moving one electrode affects the spacing from all other electrodes.
However, this makes the entire treatment procedure much longer.
The longer procedure makes it riskier for the patient since the patient would have to stay on an operating table much longer, often with an exposed body portion to be treated.
The longer procedure also makes the procedure more expensive.

Method used

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  • System and Method for Increasing a Target Zone for Electrical Ablation
  • System and Method for Increasing a Target Zone for Electrical Ablation
  • System and Method for Increasing a Target Zone for Electrical Ablation

Examples

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example 1

[0095]If V=2495 Volts; a=0.7 cm; and A=650 V / cm;

[0096]Then b2=1.376377

[0097]and then a cassini curve can be plotted by using eq. (5) above by solving for r, for each degree of theta from 0 degrees to 360 degrees.

[0098]A portion of the solutions for eq. (5) are shown in Table 1 below:

[0099]where M=a2 cos(2*theta); and L=sqrt(b4−a4 sin2(2*theta))

TABLE 1Thetar =r =r =r =(degrees)sqrt(M + L)−sqrt(M + L)sqrt(M − L)−sqrt(M − L)01.366154−1.366150011.366006−1.366010021.365562−1.365560031.364822−1.364820041.363788−1.363790051.362461−1.362460061.360843−1.360840071.358936−1.358940081.356743−1.356740091.354267−1.3542700101.351512−1.3515100111.348481−1.3484800121.34518−1.3451800131.341611−1.3416100141.337782−1.3377800151.333697−1.333700

[0100]The above eq. (6) was developed according to the following analysis.

[0101]The curve from the cassini oval equation was calibrated as best as possible to the 650 V / cm contour line using two 1-mm diameter electrodes with an electrode spacing between 0.5-5 cm a...

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Abstract

System for increasing a target zone for electrical ablation includes a treatment control module executable by a processor. The control module directs a pulse generator to apply pre-conditioning pulses to subject tissue cells in a pre-conditioning zone to electroporation, the pre-conditioning zone being smaller than a target ablation zone. After the pre-conditioning pulses have been applied, the control module directs the pulse generator to apply treatment pulses to electrically ablate the tissue cells in the target ablation zone. The pre-conditioning pulses cause the pre-conditioning zone to have a much higher conductivity so that the zone acts as a larger electrode area when the treatment pulses are applied, which results in a much larger target ablation zone than otherwise possible.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority under 35 U.S.C. 119(e) to U.S. Provisional Application No. 61 / 596,436, filed Feb. 8, 2012, which is incorporated by reference herein.[0002]This application is also related to PCT International Application Number PCT / US10 / 29243, filed Mar. 30, 2010 and entitled “System and Method for Estimating a Treatment Region for a Medical Treatment Device and for Interactively Planning a Treatment of a Patient”, which is incorporated herein by reference.FIELD OF THE INVENTION[0003]The present invention relates to a medical treatment device for ablating a target tissue zone. More particularly, the present application relates to a system and method for increasing a target tissue zone for electrical ablation.BACKGROUND OF THE INVENTION[0004]Devices for delivering therapeutic energy such as an ablation device using irreversible electroporation (IRE) include a pulse generator and one or more electrodes coupled to the genera...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B18/14
CPCA61B18/14A61B2018/00613A61B2018/00875A61B2018/143A61B2018/00827
Inventor CALLAS, PETERJOE, WESLEY CHUNG
Owner ANGIODYNAMICS INC
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