12 results about "Aminosugar" patented technology

The present disclosure relates to crystalline forms of N-{3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-allylidene}-aminoguanidinium salts having high solubility. The disclosure also relates to use of said crystalline forms in medicine.

The present invention addresses the problem of providing a method for reducing the iminosugar content in silkworm powder. The method that solves this problem is characterized by comprising a step for obtaining an extraction residue extracted from processed silkworms by using a nonpolar organic solvent.

The present invention relates to specific compounds of imino sugars with piperidine rings, which have a D-glucose configuration and contain a quaternary center located at the alpha position of the nitrogen of the piperidine ring. These compounds have the ability to stabilize human acid alpha-glucosidase while being selective relative to other glycosidases. The compounds are particularly useful as chaperone molecules for the enzyme for the treatment of Pompe disease.

The invention provides a medicinal preparation for treating animal mycoplasma infection and application thereof, and particularly relates to the technical field of application of veterinary chemical medicinal preparations. The active ingredients of the pharmaceutical preparation are an amino glycosamine compound and a transfer factor. The pharmaceutical preparation is prepared from a composition of an amino sugar amine compound, a transfer factor and one or more pharmaceutical adjuvants, or the pharmaceutical preparation is a mixed preparation of an amino sugar amine compound injection and a transfer factor injection. According to the pharmaceutical preparation, the amino glycosamine compound and the transfer factor are combined for injection, so that the dosage of antibiotics can be reduced, the treatment effect of poultry mycoplasma diseases can be improved, and the clinical application prospect is wide.

The compositions disclosed herein are contemplated for use in the treatment and prevention of diseases caused by heparan sulfate accumulation, including mucopolysaccharide storage disorders, Alzheimer's disease, and cancer. These compositions include iminosugars belonging to the L-stereoseries and derivatives thereof as active ingredients. The L-iminosugar of the present invention can reduce the level of heparan sulfate in patient cells affected by mucopolysaccharide storage diseases and cancers, and reduce the accumulation of amyloid plaques in a neurodegenerative disease model. Thus, the use of these compounds prevents the occurrence of symptoms associated with these diseases, thereby improving the quality of life and longevity of patients suffering from diseases characterized by heparan sulfate accumulation.

A method for selectively leaching valuable metals from spent ternary lithium-ion battery cathode materials using an amino sugar eutectic solvent relates to the field of hydrometallurgy, providing an efficient method for extracting valuable metals from spent lithium-ion batteries. The hydrophilic eutectic solvent provided in this application comprises D-glucosamine hydrochloride and betaine hydrochloride. Valuable metals in spent ternary lithium-ion battery cathode materials are leached using the aforementioned eutectic solvent. The eutectic solvent of this application uses inexpensive raw materials, is widely available, and has low preparation costs. The leaching method for valuable metals in spent ternary lithium-ion battery cathode materials of this application can replace traditional pyrometallurgical processes and hydrometallurgical processes using strong acids and alkalis as leaching agents, achieving a green and environmentally friendly goal.

A composition comprises: (i) at least one C-glycoside; (ii) at least one aminosugar; and (iii) at least one Inonotus obliquus extract. A non-therapeutic method for caring for keratin materials comprises applying said composition to the keratin materials.

Described herein is a general solution to 1,2-cis-amino-glycoside synthesis through an iron-catalyzed, exclusively 1,2-cis-selective glycal aminoglycosylation via cooperative atom transfer catalysis. Further described is a 1,2-cis-selective glycal aminoacyloxylation method for 2-amino saccharide synthesis. The methods are effective for a wide variety of glycosyl donors with consistently high stereoselectivity and excellent functional-group compatibility, which facilitates late-stage amino group incorporation for complex-carbohydrate and other biologially-related molecule synthesis.

The invention provides SJMHE1 polypeptide loaded glycogen hydrogel, a preparation method and application in wound healing promoting drugs, natural glycogen AG is subjected to amination modification through diethylenetriamine DETA, then SJMHE1 polypeptide is loaded, and then the SJMHE1 polypeptide loaded glycogen AG is mixed with polyvinyl alcohol PVA to obtain amino glycogen AG-SJMHE1 polypeptide-PVA gel, namely the SJMHE1 polypeptide loaded hydrogel. The SJMHE1 polypeptide loaded glycosyl hydrogel provided by the invention can accelerate the repair of skin injury by promoting collagen deposition and angiogenesis. The natural glycogen nanoparticles are non-toxic and biodegradable, the manufacturing process is easy to control, the natural glycogen nanoparticles can be obtained on a large scale, and the glycogen loaded SJMHE1 polypeptide hydrogel is low in cost, easy to prepare and high in safety, has remarkable application potential and provides a new direction for skin injury repair.

The present application provides novel iminosugars and their use as glucosidase inhibitors. The present inventors have discovered that certain deoxynojirimycin derivatives may be effective in inhibiting glucosidases. In particular, such deoxynojirimycin derivatives may be useful for treating a disease or condition where inhibiting glucosidase may be important.

The invention belongs to the technical field of biological medicines, and particularly relates to uridine-5 '-diphosphate polydeoxy diamino sugar as well as a preparation method and application thereof. According to the invention, uridine-5 '-diphosphate-N-acetyl-glucosamine is used as a substrate to prepare UDP-kasuramine and a new structural analogue UDP-3 ''-hydroxyl-kasuramine of the UDP-kasuramine. The compound can be used as a medical intermediate for preparing commercial agricultural and medical antibiotic kasugamycin and derivatives thereof without / with low toxic and side effects. The method is simple and convenient to operate, mild in condition, environment-friendly and relatively high in conversion rate, and has a good application prospect.

Provided are skincare compositions comprising: a compound having retinol-like activity and an N-acetyl compound selected from the group consisting of N-aldosamines, N-acetylated amino acids and combinations thereof. Also provided are methods for treating skin comprising topically applying these compositions. Also provided are skincare compositions comprising 3-(4- farnesyloxyphenyl)-propionic acid; and a derivative of an aminosugar selected from the group consisting of N-acetyl-ribosamine, N-acetyl-arabinosamine, N-acetyl-glucosamine, N-acetyl- galactosamine and N-acetyl-mannosamine, and combinations thereof, wherein the composition is in the form of a solution, suspension, emulsion, lotion, cream, serum, gel, stick, spray, ointment, liquid wash, soap bar, shampoo, hair conditioner, paste, foam, powder, mousse, shaving cream, hydrogel, or film-forming product.