158 results about "Glycal" patented technology

The invention discloses a chitosan-based composite adsorbent capable of synergistically and efficiently removing positive and negative ions of heavy metals and a preparation method thereof and belongs to the technical field of heavy metal wastewater treatment. The preparation method of the chitosan-based composite adsorbent comprises the steps that A, chitosan powder is dissolved in an acetic acid solution to form a chitosan mother solution, ferric sulfate and polyethyleneimine are put into the chitosan mother solution, uniform stirring is performed, and a mixed mother solution is obtained after preliminary crosslinking is performed by using epoxy chloropropane; B, the mixed mother solution is pumped into a coagulating bath, and composite microspheres are obtained through precipitation solidification; C, the composite microspheres are taken out and put into asodium hydroxide water solution, crosslinking is performed by using epoxy chloropropane to obtain crosslinked microspheres, and the crosslinked microspheres are washed by using distilled water till the crosslinked microspheres are neutral and then are dehydrated and saved for standby application. The chitosan-based composite adsorbent is simple in preparation, low in cost, stable in structure, superior in performance, can synergistically and efficiently remove the positive and negative ions of heavy metals and has wide application prospect on the aspect of synergistic control of combined pollutants of heavy metal positive and negative ions.

A solution having improved mold and mildew stain removing properties on hard surfaces, that is easier to handle (less corrosive and less malodorous) and that is environmentally friendly. The mold and mildew stain removing solution includes the following components: a surfactant selected from the group consisting of alcohol ethoxylates, alkyl sulfates, alkyl ether sulfates, alpha olefin sulfonates, alkyl phosphates, alkyl amidopropyl betaines, alkyl betaines, amphoacetates, amphoproprionates, amphosulfonates, amine oxides, alkanolamides, sulfosuccinates, and sultaines, a solvent, and at least one chelating agent. The solution may further comprise a hydrotrope, a diluent, a preservative, and / or a fungicide. The surfactant is preferably an alcohol ethoxylate. The hydrotrope is preferably lauramine oxide. The solvent is preferably a glycol ether. The chelating agents are preferably sodium gluconate and a solution of the trisodium salt of methyl glycine diacetic acid.

(Object): There are provided (1) an optically active a-amino acid derivative, a stereoselectively useful intermediate for the synthesis of pharmaceutical or agrochemical products, which derivative is an optically active quaternary ammonium salt that, when used as an axially chiral spiro phase-transfer catalyst in the asymmetric alkylation of a glycine derivative, gives a high stereoselectivity toward substrates having a small molecule such as methyl iodide, or secondary alkyl halides, and a method for producing the same; and (2) a novel optically active quaternary ammonium salt that is a high performance axially chiral spiro phase-transfer catalyst used in the asymmetric alkylation of a glycine derivative, and in which each ring of the spiro-structure has the same structure that is advantageous in terms of the number of steps involved in the synthesis of the catalyst, and a method for producing the same and a method for recovering the same. (Solving means): To achieve the objects, (1) an axially chiral spiro-ammonium salt that incorporates an alkyl- or aryl-substituted silyl group as a substituent on the aromatic ring is used as a phase-transfer catalyst in the asymmetric alkylation of a glycine derivative, and (2) an axially chiral spiro-ammonium slat that incorporates a substituent encompassing a perfluoro alkyl group is used in the asymmetric alkylation of a glycine derivative and thereafter is recovered using a fluorous solvent.

The invention relates to a pantoprazole sodium freeze-dried preparation for injection and a preparation method thereof. The freeze-dried preparation is formed by preparing components containing the following parts by weight into liquor for freeze drying after dissolving into water for injection: 60 to 80 parts of pantoprazole sodium, 100 to 300 parts of glycocoll, 50 to 100 parts of glucose and aright amount of sodium hydroxide. According to the pantoprazole sodium freeze-dried preparation for the injection, which is disclosed by the invention, the problem of stability of a preparation is solved; and moreover, an adverse reaction existing in a traditional product is lowered.

The invention relates to a formaldehyde fluorescence probe and a preparation method and an application thereof, and belongs to the technical field of preparation of formaldehyde probes. The formaldehyde fluorescence probe has the structural formula defined in the specification; the formaldehyde response time is about 10 seconds, and thus rapid detection is realized; the formaldehyde fluorescence probe can resist interference of acetaldehyde, glyoxal, methylglyoxal, benzaldehyde, alanine, glycine, serine, arginine, cysteine, glutathione, glucose, hydrogen peroxide and hypochlorous acid and has good specificity. The formaldehyde content in a solution can be determined through observing the change degree of spectra in a fluorescence spectrophotometer, and thus quantitative detection is achieved; the lower limit of detection is 7.7*10<-7> mol / L. Whether the solution contains formaldehyde and the general concentration of formaldehyde are determined through observing color changes of the solution via naked eyes. In addition, with use of the probe II, detection of formaldehyde in biological samples can be realized. The preparation method of the probe II is simple, and the yield is relatively high.

The invention discloses a degradable electricity-conducting biomedical polymer material, which has a molecular constitution as shown in formula I: the polymer material takes the polymer in the formula, which comprises polyphosphazene, chitosan, polyvinyl alcohol, poly-beta-malic acid or modified polyester, as the main chain, a conductive group and a degradable group are grafted, and the modified polyester is lactic acid, polyglycolide, polycarbonate, polyanhydride, polycaprolactone or copolymers between each two thereof; the conductive group comprises oligo-pyrrole, oligo-thiophene, oligo-aniline or copolymers between each two thereof; the degradable group mainly comprises: (1) amino: glycine ethyl ester, phenylalanine ethyl ester, imidazole and the like; and (2) alkoxy: glycerol, glucose, lactic acid, p-methyl phenol, glycolic acid and polyester. The polymer material has degradability and conductivity and can be prepared into guide pipes, suture threads, membranes, sheet bodies, block bodies and materials for frames of tissue engineering.

The invention relates to a method for synthesizing glutathione using yeast cells. Gamma-GCS and GS in yeast cells are used, glucose is used as the energy, an intracellular glucolysis system is used to produce triphosadenine, glutamic acid, cysteine and glycin in reaction liquid are synthesized to form glutathione; saccharomyces cerevisiae, baker's yeast, candida and other yeast cells are permeabilized and then react in a reaction liquid composed of phosphate buffer, MgCl2.6H2O, CaCl2.2H2O, glucose, L-glutamic acid and L-cysteine, gamma-L-glutamoyl L- cysteine is produced, then glycin is added to produce glutathione; in the two-stage reaction, the inhabitation effect of glutathione to gamma-GCS catalytic reaction is greatly reduced; glutathione produced by the method has obviously improved product concentration and reaction yield.

A high-density powdered detergent composition which has a bulk density of 0.6 to 1.2 g / ml and which comprises 0.5 to 30% by weight of (a) a glycine-N,N-diacetic acid derivative, 5 to 45% by weight of (b) a nonionic surfactant having an HLB value of 10.5 to 15.0, 0.5 to 18% by weight of (c) an anionic surfactant and 1 to 30% by weight of (d) an aluminosilicate, each percentage being based on the total weight of the composition, and the weight ratio of the component (b) to the component (c) lying between 90:1 and 60:40. This composition contains both a glycine-N,N-diacetic acid derivative which is a builder excellent in biodegradability and sequestering power and an inorganic builder such as zeolite or crystalline silicate, and exhibits high detergency.

The invention discloses a preparation method of a compound of a formula (I) and a derivative thereof, being characterized by comprising the following steps: (1) obtaining a compound of a formula (II) by esterification reaction of glycine and proper alcohol under the conditions of proper temperature and catalyst; (2) generating a compound of a formula (III) by acylation reaction of the compound of the formula (II); (3) forming a compound of a formula (IV) under acid environment after condensation of the compound of the formula (III) and ethyl formate under alkaline environment; and (4) generating the compound of the formula (I) by oxidation reaction of the compound of the formula (IV) and an oxidant, wherein R1 is selected from alkyl of C1-6 and optional substituted aryl and R2 is selected from C1-4 and optional substituted aryl. The method has easily-obtained materials, simple reaction, moderate and controllable synthesis conditions, high yield of obtained products, little pollution and applicability to industrialized production.

This invention relates to methods for preparing new menthol derivatives, i.e., N, N-dimethyl menthol glycinate, N, N-diethyl menthol glycinate and N, N-dihydroxyethyl menthol glycinate. This invention comprises three different methods for synthesizing menthol derivatives. Method 1 comprises: reacting chloroacetyl chloride and menthol at room temperature for 1-3 h, and reacting with amine at room temperature for 1-3 h to obtain the target products. Method 2 comprises: refluxing chloroacetic acid and menthol in cyclohexane in the presence of a Lewis acid catalyst for 1-3 h, and reacting with amine at room temperature for 1-3 h to obtain the target products. Method 3 comprises: refluxing N,N-disubstituted glycine and menthol in cyclohexane in the presence of a Lewis acid catalyst for 1-3 h to obtain the target products. The new menthol derivatives can be used as transdermal agents.

The invention belongs to the technical field of organic chemistry, in particular relating to a preparation method for an Arabian glycal. The method adds 1-bromination acetylation arabinose into a reaction system which comprises zinc powder, sodium dihydrogen phosphate, acetone and water, and D-acetylation Arabian glycal is generated through the reaction; after the generated D-acetylation Arabian glycal is dissolved in methanol, potassium carbonate is added into the solution, and D-Arabian glycal is generated through the reaction. The preparation method for the Arabian glycal has the advantages of simple operation, high yield, short reaction time, low cost, few three wastes, little environmental pollution and easy industrialization.

A surfactant composition comprising a sugar-based surfactant comprising a C8-C16 alkyl glucoside, a C8-C16 alkyl polyglucoside, or a combination of a C8-C16 alkyl glucoside and a C8-C16 alkyl polyglucoside; a C8-C18 amphodiacetate; a C8-C16 acyl sarcosinate, a C8-C16 acyl glutamate, a C8-C16 acyl glycinate, or a combination thereof; and optionally a C8-C14 acyl lactylate, wherein the composition is free of sulfated anionic surfactants.

The invention discloses an autolysable high-strength quick-adhesion hydrogel, a preparation method and applications thereof, wherein the vinyl monomer N-acryloylglycine of a glycine derivative with good biocompatibility and nanometer active inorganic nanoparticles are used as reactants and are subjected to one-step free radical copolymerization under ultraviolet irradiation by using a photoinitiator to prepare the autolysable high-strength quick-adhesion hydrogel. According to the invention, through a large number of hydrogen bonds formed between the PACG molecular side chains in the formed hydrogel, the ion complexing of the carboxyl at the tail end of the molecular chain and the inorganic ions, and the physical adsorption effect between the polymer chain and the nanoparticles, the hydrogel is endowed with excellent mechanical properties, has extremely good adhesion strength to various matrixes, and shows good biocompatibility.

The invention belongs to the technical field of the preparation of ceramic powder, and in particular relates to a method for producing nano chromium nitride powder. The technical process comprises the following steps of: (1) dissolving chromic nitrate, glycine or glycine and glucose in a certain proportion in distilled water; (2) heating and stirring, volatilizing, concentrating and bubbling the liquid to obtain precursor powder; and (3) introducing ammonia to the precursor powder or power untreated in a furnace at 600-1000 DEG C to react for 0.5-20 hours, wherein the ammonia flow is 0.25-5L / min. The method provided by the invention is simple in preparation process, short in production period and easy to realize industrial production, and chromium nitride powder obtained is better in dispersibility.

The invention relates to preparation of N, N-dimethyl glycine ester chemical products, particularly relates to a preparation method of N,N-dimethyl glycine ester based on silica gel sulfonic acid serving as a catalyst, and belongs to the field of chemical industries. The preparation method is characterized in that carboxylic acid and alcohol are used as raw materials for carrying out esterification reaction so as to obtain the N,N-dimethyl glycine ester, the catalyst for esterification reaction is the silica gel sulfonic acid, the carboxylic acid is N,N-dimethyl glycine, and the alcohol is fatty alcohol with 1-12 carbon atoms. The synthesis of the silica gel sulfonic acid serving as the catalyst involved in the invention is simple, raw materials for synthesis of the catalyst are cheap and easily available, and the catalyst has high catalytic activity; the catalyst is recycled and reused through simple filtration, so that the production cost is saved; the corrosion of sulfuric acid, phosphoric acid and the like to equipment is avoided; by adopting the technology, the yield is high, and the conversion rate can reach above 95%; after completion of reaction, the follow-up treatment is simple; the atom economy in the whole reaction process is good, and no other waste products are generated except for water.

The invention discloses a preparation method of etoposide, teniposide and analogs of etoposide and teniposide. The preparation method includes the following steps of 1, selective protection of 4'domethylpodophyllotoxin4'hydroxy; 2, introduction of 4 hydroxy hydroxyl; 3, removal of a protecting group. The method is mild in reaction condition and environmentally friendly, and the yield and purity of the products are high.

The invention provides drought-resisting and water-holding self-loosening type special water-retaining agent and special matrix for Epipremnum aureum and a preparation method of the special matrix, and belongs to the technical field of plant planting. The drought-resisting and water-holding self-loosening type special water-retaining agent for Epipremnum aureum is prepared from, by weight, 5-30 parts of high molecular material, 20-50 parts of humic acid, 20-50 parts of vermiculite, 0.0005-0.001 part of glucosan glycal. The high molecular material is acrylamide-acrylate copolymer crosslinking agent or starch grafting acrylate copolymer crosslinking agent; the acrylamide-acrylate copolymer crosslinking agent is polyacrylamide, sodium polyacrylate, potassium polyacrylate or ammonium polyacrylate. The preparation method is simple, the special matrix for Epipremnum aureum is able to provide nutrient elements for plant growth, improve soil and promote plant growth; moreover, the raw material is simple, and the matrix is suitable for family preparation independently; after the watering once, the water retaining can last for over 2 months.

The invention relates to a novel process for preparing ascorbyl glucoside. Starch sugar group and L-ascorbic acid or salt of L-ascorbic acid are used as raw materials to prepare ascorbyl glucoside under the condition of an additional energy field, so that the reaction time can be obviously shortened, the conversion rate of the ascorbyl glucoside is improved, unreacted sugar is removed through a microbiological fermentation method, energy conservation, emission reduction, economy and high efficiency can be achieved by using the method, then products of which the purity is greater than 95% can be extracted through ion exchange chromatography separation, and the ascorbyl glucoside crystals of which the content is greater than 99.5% can be prepared through concentration and cooling crystallization.

The invention relates to a zinc gluconate sugar tablet preparation and a preparation method thereof. The sugar tablet comprises the following components by mass: 93.24-160 parts of zinc gluconate and pharmaceutic excipients such as 1460-2500 parts of white sugar, 2910-5000 parts of maltose syrup or glucose syrup, 30-52 parts of glycine, 438-750 parts of purified water and 30-52 parts of fruit flavoring agents. The preparation is prepared by dissolving sugar at high temperature, boiling sugar under vacuum, etc. The form of the preparation is semi-transparent hard sugar tablet and the preparation is the buccal tablet. The sugar tablet is dissolved in the mouth, so that the zinc ions can permeate the nose, throat and susceptible tissues in the nasal sinus to be combined with the influenza virus receptor to prevent the influenza virus from further spreading among the cells so as to achieve the aims of treating cold and alleviating cold symptoms.

The invention relates to a Xuanwei Ham essence, comprising the following raw materials, by weight: 0-10 parts of glucose, 0-3 parts of D-xylose, 0-5 parts of glycin, 0-4 parts of L-cysteine, 0-4 parts of DL-methionine, 0-4 parts of VC, 0-6 parts of VB1, 5-20 parts of pig bone oil, 10-40 parts of pig bone clear soup, 3-40 parts of pig bone hydrolyzate, 10-40 parts of Xuanwei Ham hydrolyzate and 10-30 parts of salt. The essence product of the invention is natural, has strong cooking sense, mellow and rich fragrance and lasting aftertaste.

The invention discloses a preparation method of a glucosyl modified quantum dot fluorescent probe. The preparation method comprises: adopting D-glucose as a raw material, carrying out hydroxyl complete protection and terminal glycosylation, adding a N,N-dimethylformamide solution and potassium thioacetate to catalyze, removing the protection group through sodium methoxide / methanol to obtain mercapto derivatized glucose, and modifying the mercapto derivatized glucose on the surface of quantum dots through ligand exchange to obtain the glucosyl modified quantum dot fluorescent probe. According to the present invention, the prepared glucosyl modified quantum dot fluorescent probe is used for detecting the pesticide fenpropathrin content; and the glucosyl modified quantum dot fluorescent probe has the specific recognition ability of sugar and the special properties of quantum dots, and further has advantages of good water solubility and long stabilization time, and the preparation method has advantages of short synthesis route of the glucosyl modified body, simple synthesis operation, simple preparation method of the modified quantum dots, and rapid preparation.

The invention provides a preparation of a water soluble saccharide fluorescent molecular probe as well as a direct and rapid detection for iron ions in water and a biological tissue. The fluorescent molecular probe obtains very high selectivity and sensitivity for iron ions in water and serum; after the fluorescent molecular probe is selectively combined with the iron ions, the color change of the solution from yellow to red brown can be observed by naked eyes; and the lower detection limit can reach 10-6 M. Without need of instruments, the field real-time direct and rapid detection can be carried out. The fluorescent molecular probe can be prepared to obtain an iron ion detecting test paper and a detecting kit and can be also coated with films to obtain a portable solid detector by using viscosity of saccharide compounds. The specific structure of the saccharide fluorescent molecular probe (taking a glucosamine ligand for example): except for glucosamine, the saccharide ligand can be also other saccharide compounds and derivatives thereof.

The invention discloses a shear-resistant salt-tolerant fracturing fluid thickening agent, which is prepared by carrying out polymerization reaction on raw material monomers, namely acrylamide and a monomer A, in solvent deionized water under the action of a cross-linking agent N,N'-methylene bisacrylamide and an initiator, wherein the monomer A is one of acryloyl glycine amide, acryloyl glycineor vinyl guanidine amine, the initiator is ammonium persulfate or 2-hydroxyl-2-methyl propyl benzene ketone, and the thickening agent is a colloidal thickening agent prepared by carrying out polymerization reaction on acrylamide and a monomer A at the heating temperature of 40-50 DEG C or under the condition of ultraviolet lamp irradiation initiation. According to the thickening agent, a stable network structure is formed by introducing a reversible multi-hydrogen bond supramolecular structure, permanent damage of high-speed shearing to a system structure is effectively resisted, and meanwhilethe salt tolerance of the thickening agent is improved.

The invention discloses a preparation method of Ag / ZnFe2O4 / Fe3O4 heterogeneous magnetic microsphere with controllable morphology. The preparation method includes the steps of: (1) taking crystalline ferric chloride or crystalline ferric nitrate and crystalline zinc acetate as the raw materials, adopting glycine or L-aspartic acid as the complexing agent and taking ethylene glycol as the solvent, mixing the substances, then putting the mixture on a magnetic stirrer, adding the stirred solution into a hydrothermal reaction kettle, then flushing a beaker with ethylene glycol, and conducting pouring into the reaction kettle; (2) putting the reaction kettle into a constant-temperature blast oven, centrifuging the powder generated in the reaction kettle by a centrifugal machine at the end of thereaction, then respectively using anhydrous ethanol and deionized water for alternate washing repeatedly, and then putting the washed powder into a vacuum drying oven for drying; and (3) pouring silver nitrate, glucose and ZnFe2O4 / Fe3O4 composite powder into the beaker, adding deionized water for dissolving, stirring the substances uniformly, then putting the beaker on an ultrasonic cleaner for cleaning, then utilizing deionized water and anhydrous ethanol for mixed centrifugal washing, and then performing drying, thus obtaining Ag / ZnFe2O4 / Fe3O4 multi-component nano-powder.

The invention relates to a synthesis method of glycine derivatives. The synthesis method comprises that in an organic solvent, a glycinate compound and indole as raw materials and a Lewis acid additive undergo a reaction in the presence of dye EosinY as a catalyst at a normal temperature in O2 atmosphere under pressure of 1 atm for 40h, and the products are separated and purified. Compared with the prior art, the synthesis method solves problems of low reaction efficiency, high temperature requirements, high catalyst cost and heavy metal pollution, has the characteristics of high reaction yield, simple operation and environmental friendliness, and can be widely used in organic synthesis methodology and natural product synthesis.

The invention belongs to the technical field of organic chemistry, and particularly relates to a method for preparing acetylated glycal, acetylated disaccharide glycal and benzoylated glycal. Acetylated glycosyl bromide or acetylated disaccharide bromide or benzoylated glycosyl bromide is added into a system of PEG and water, and then Zn powder is added to carry out room temperature reaction to respectively generate the acetylated glycal or the acetylated disaccharide glycal or the benzoylated glycal. The invention has the advantages of simple operation, short process, high yield, fast reaction, low cost, fewer three wastes, energy saving, environment protection, easy industrialization and the like.

This invention involves a synthetic method to a new diarylheptanone compounds separated from high-grade plant. This kind of diarylheptanone compounds has general structure formula shown as follows, it is 1-ketonyl-1,7-diarylheptanone compounds. In general structure formulaó±, R1 should be H, H2, OH, ú¢O, -(CH2)m-, OR' ; n=1 to 5; m=1 to 40. Compounds above-mentioned are distilled from altitude plant such as seed plant, passing a series of steps, get diarylheptanone compounds ,it has good function of medical treatment and health care.