18 results about "Glycal" patented technology

This invention provides an oil-purifying cleansing mud and its preparation method. The cleansing mud, by weight, comprises 1-5 parts of a viscosity modifier, 0.01-0.1 parts of a chelating agent, 10-20 parts of a moisturizer, 15-25 parts of a surfactant, 0.1-1 parts of a thickener, 0.1-5 parts of a cleanser, 0.1-2 parts of an antioxidant, 0.1-1 parts of a fragrance, and 50-75 parts of water. The surfactant is a combination of sodium cocoyl glycinate, lauryl hydroxysulfonate betaine, cocoyl glutamic acid, decyl glucoside, potassium cocoyl glycinate, and cetearyl alcohol polyether-25. This oil-purifying cleansing mud, through the use of surfactants, cleansers, and moisturizers, gently cleanses pores, absorbs oil and dirt, and simultaneously soothes the skin, preventing dryness and tightness. The synergistic combination of these components achieves a balance between cleansing, oil removal, and gentleness, precisely regulating the skin's balance and thus enhancing the consumer experience.

This invention relates to a chiral preparation method for florfenicol. Specifically, the method uses p-methylsulfonylbenzaldehyde and glycine ester as starting materials, and synthesizes the key chiral intermediate I through an asymmetric aldol reaction process under the action of a pyridinium salt carbonyl catalyst. Subsequently, through reduction, cyclization, fluorination, and hydrolysis ring-opening reactions, the chiral product florfenicol is obtained. Compared with existing technologies, this invention utilizes the strong catalytic ability of small-molecule pyridinium salt carbonyl catalysts, starting from inexpensive and readily available raw materials, to efficiently control the stereoselectivity of the aldol reaction process, highly selectively constructing the two chiral centers on the florfenicol structure, obtaining the desired chiral configuration, and finally synthesizing florfenicol. The preparation method of this invention is simple, rapid, and efficient.

Providing a cosmetic that is not sticky, has excellent skin affinity, and has a smooth feeling. 【Solution means】The cosmetic according to the present disclosure contains (A) 0.1% by mass to 5% by mass of a glycine derivative represented by formula (1) or a salt thereof, (B) niacin or a derivative thereof, (C) a higher alcohol having 14 to 22 carbon atoms, (D) a hydrophilic polyoxyethylene alkyl ether, and (E) a glycerin monoalkyl ether. TIFF2026105749000006.tif43169 (In the formula, R 1 and R 2 each independently represents H, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, etc., and R 3 represents H, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R 1 , R 2 , R 3 do not simultaneously become H.)

This invention belongs to the field of organic synthesis technology, specifically relating to a creatine glycinate and its preparation method, comprising the following steps: pretreatment, drying creatine monohydrate, passing glycine through a 100-mesh sieve and storing it in a desiccator for later use, and selecting a reaction solvent; raw material dissolution, adding the reaction solvent to a reaction vessel, starting stirring and heating, adding creatine monohydrate, and stirring at a constant temperature until completely dissolved, finally obtaining a creatine solution; complexation reaction, adding glycine, increasing the stirring rate and heating after the addition is complete, maintaining the temperature for the complexation reaction, using staged stirring until the complexation reaction is complete; after the reaction is complete, using a gradient cooling method; crystallization and ripening, followed by constant temperature and low-speed stirring for 2 hours, then allowing the crystals to settle completely; after filtration, vacuum drying is performed to finally obtain creatine glycinate. This application solves the problems of uneven reaction, poor crystal quality, and low purity and yield in existing processes, achieving efficient and high-quality preparation of creatine glycinate.

This invention relates to a method for preparing chiral drosildopa. Specifically, the method uses compound 1 and glycine ester as starting materials, and an asymmetric aldol reaction occurs under the action of a pyridinium salt carbonyl catalyst, followed by hydrolysis to obtain drosildopa. Compared with the prior art, this invention utilizes the strong catalytic ability of small molecule pyridinium salt carbonyl catalysts, starts with inexpensive and readily available raw materials, reduces the steps of introducing and removing protecting groups, shortens the synthetic route, and efficiently synthesizes optically pure drosildopa. Furthermore, the preparation method of this invention is simple to operate and environmentally friendly.

This invention relates to the field of phase change energy storage materials technology, specifically to a high-energy-storage composite phase change material for low-temperature applications and its preparation method. Addressing the problems of high supercooling, slow crystallization rate, and poor heat transfer performance in existing low-temperature phase change materials, this invention uses a glycylglycine aqueous system as the high-energy-storage matrix, introduces organic sugar alcohols as phase change temperature regulators, and constructs heterogeneous nucleation sites by adding inorganic nanoparticles. These nanoparticles significantly reduce the nucleation energy barrier of the system, effectively suppressing supercooling and improving the internal heat transfer efficiency of the material. The material obtained by this invention crystallizes rapidly and releases heat efficiently, making it widely applicable in cold chain logistics and food preservation.

This invention provides an absorbent for capturing carbon dioxide and a method for capturing carbon dioxide. By volume percentage, the absorbent comprises 20-60% glycine salt aqueous solution, 10-50% triethylene glycol monomethyl ether, 5-10% ethylene glycol, and the balance being water. This absorbent combines the advantages of glycine salt systems, such as low volatility, non-toxicity, safety, and better antioxidant degradation resistance, while avoiding the risk of solid precipitates forming after absorption by the glycine salt system, which could cause pipeline blockage.

To provide an oil-in-water emulsion cosmetic that blends easily into the skin during application, provides excellent moisturizing properties after application, and is less sticky. [Solution] (A) Glycine derivative or a salt thereof, (B) Hydrophilic nonionic surfactant selected from the group consisting of POE castor oil derivatives and hydrogenated castor oil derivatives, (C) Water-soluble solvent, (D) an oil-in-water emulsion cosmetic comprising oil and (E) water. The content of component (A) is 0.3 to 5% by mass based on the total mass of the cosmetic. This cosmetic comprises emulsion particles containing component (B) dispersed in the aqueous phase.

The objective of this invention is to provide an oil-in-water emulsion cosmetic that maintains or improves the skin's dryness and tightness even when containing glycine derivatives and / or their salts. The solution is an oil-in-water emulsion cosmetic comprising (A) a glycine derivative and / or its salt as shown in formula (a), (B) a polyoxyalkylene-modified silicone, (C) an oil, and (D) water, wherein the content of component (A) is 0.1% by mass or more and 7% by mass or less, based on the total mass of the cosmetic. 3 -O-C(=O)-CH2-NR 1 R 2 (a)

To provide a cosmetic product that blends well with the skin and provides excellent firming and tightening effects. [Solution] The cosmetic composition contains (A) a glycine derivative represented by formula (1) or a salt thereof, (B) a liquid oil that is liquid at 25°C and contains at least one selected from the group consisting of silicone oil and polyhydric alcohol fatty acid esters, and (C) a solid or semi-solid oil that is solid at 25°C and contains at least one selected from the group consisting of glyceryl monoalkyl ether, higher alcohols having 18 or more carbon atoms, and candelilla wax. TIFF2026111285000010.tif43169 (R 1 and R 2 R independently represents a hydrogen atom, alkyl group, alkenyl group, aryl group, aralkyl group, aminomethylcarbonyl group, amidino group, alkylcarbonyl group, etc. 3 (This represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group.)

The application relates to the technical field of roxadustat, and particularly discloses a preparation method of roxadustat, which comprises the following steps: S1, taking 4-bromobenzyl bromide as a starting raw material, refluxing 4-bromobenzyl bromide and sodium methoxide in methanol to prepare an intermediate 2; S2, subjecting the intermediate 2 to a Friedel-Crafts acylation reaction with acetic anhydride to prepare an intermediate 3; S3, subjecting the intermediate 3 to an Ullmann coupling reaction with phenol in toluene by using glycine copper as a catalyst to prepare an intermediate 4; the starting raw material is 4-bromobenzyl bromide, the raw material is easy to obtain and low in price, a low-cost conventional reagent is used as a catalytic system, and cheap catalytic systems are used in key reactions, and low-cost alkali-solvent combinations are selected for steps such as aminolysis, so that the preparation cost is greatly compressed from the aspects of raw materials and reagents.

This invention provides a method for controlling 3-MCPDE in oils and fats, belonging to the field of oil and fat technology. The reaction steps are as follows: glycine and xylose are added to soybean enzymatic hydrolysate, stirred, and then zinc gluconate is added for ultrasonic treatment. The mixture is dried to a moisture content of 18-22% and the pH is adjusted to 6.8-7.0 to obtain the reaction system. The reaction system is then transferred to a sealed container and reacted at 168-172°C for 27-30 minutes to obtain the Maillard reaction product. The control method of this invention is simple and effective, and can effectively control the 3-MCPDE content.

The present application relates to a cosmetic. [Problem] To provide a cosmetic which is excellent in use feeling. [Solution] A cosmetic comprising (A) a glycine derivative having a specific structure or a salt thereof, (B) a polyglycerin fatty acid ester, and (C) water.

The utility model belongs to chemical equipment technical field provides a kind of reaction kettle for cocoyl glycinate synthesis, including the kettle main body being provided with inner kettle body and outer kettle body, inner kettle body is provided with reaction cavity, outer kettle body is sleeved in inner kettle body outside and forms isolation cavity between both, inner kettle body is provided with cooling jacket, cooling jacket is located in isolation cavity;Kettle main body top is provided with main feeding port, lye filling port and cocoyl chloride dropping port, lye filling port position is provided with lye filling pump, and cocoyl chloride dropping port position is provided with precooling component.The utility model provides the reaction kettle for cocoyl glycinate synthesis, by lye filling port and lye filling pump injection lye, to carry out regulation and control to pH in synthesis reaction process, simultaneously by cooling jacket and precooling component synergic temperature control, ensure that in low temperature environment state in synthesis reaction process, to improve synthesis reaction efficiency and product purity and product yield.

The present invention provides a cosmetic composition containing a high concentration of a glycine derivative or a salt thereof, exhibiting excellent usability and stability. [Solution] (A) A glycine derivative having a specific structure or a salt thereof, (B) Monohydric lower alcohols, (C) Spherical powder, and (D)Water A cosmetic composition comprising, The content of component (A) is 0.3 to 5% by mass relative to the total amount of the cosmetic. A cosmetic product in which the content of component (B) is 3% by mass or more relative to the total amount of the cosmetic product.

This invention relates to a chiral method for preparing thiamphenicol. Specifically, the method uses p-methylsulfonylbenzaldehyde and glycine ester as starting materials, and carries out an asymmetric aldol reaction in the presence of a pyridinium salt carbonyl catalyst, followed by a reduction and amidation reaction to obtain thiamphenicol. This invention utilizes the strong catalytic ability of small-molecule pyridinium salt carbonyl catalysts, starts with inexpensive and readily available raw materials, reduces the steps of introducing and removing protecting groups, shortens the synthetic route, and efficiently synthesizes optically pure thiamphenicol. Furthermore, the preparation method of this invention is simple to operate and environmentally friendly.

This invention relates to a chiral preparation method for chloramphenicol. Specifically, the method uses p-nitrobenzaldehyde and glycine ester as starting materials, and an asymmetric aldol reaction occurs under the action of a pyridinium salt carbonyl catalyst. Following reduction and amidation reactions, chloramphenicol is obtained. Compared with existing technologies, this invention utilizes the strong catalytic ability of small-molecule pyridinium salt carbonyl catalysts, starting from inexpensive and readily available raw materials, to efficiently control the stereoselectivity of the aldol reaction, and to obtain the desired stereoconfiguration product, chloramphenicol, in a single dose. The preparation method of this invention reduces the protection of active groups, shortens the chiral synthetic route of chloramphenicol, is simple to operate, and is environmentally friendly.

This invention provides a cosmetic that imparts a moisturizing sensation immediately after application and suppresses stickiness. The cosmetic of this invention comprises: (A) a glycine derivative; (B) at least one hydrophilic surfactant selected from the group consisting of polyoxyethylene hydrogenated castor oil and polyoxyethylene phytosterols; (C) at least one lipophilic surfactant selected from the group consisting of polyglycerol diisostearate, sorbitan sesquiisostearate, and sorbitan sesquioleate; (D) an oil component; and (E) water.