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36 results about "Cutaneous inflammation" patented technology

Medicinal fibre used for treating cutaneous inflammation and pain, preparation and application thereof

The invention relates to medicinal fibre used for treating cutaneous inflammation and pain, which comprises the components of cellulose acetate nano fibre, a ketoprofen ester precursor medicine and a medicinal percutaneous sorbefacient, wherein the ketoprofen ester precursor medicine accounts for 0.1-30% of the total weight of the fibre, the medicinal percutaneous sorbefacient accounts for 0.1-10% of the total weight of the fibre, and the cellulose acetate nano fibre accounts for 1-99% of the total weight of the fibre; the preparation of the medicinal fibre comprises the following steps: dissolving the ketoprofen ester precursor medicine, the medicinal percutaneous sorbefacient and the cellulose acetate into an organic solvent to prepare spinning liquid and then spinning to prepare the required medicinal fibre. The medicinal fibre has the effect of treating cutaneous inflammation and pain, has simple preparation method, convenient source of the raw materials and low cost, is friendly to the environment and is suitable for industrialized production; the fibre can be prepared into medicine-carrying clothings or other fabrics which directly contact with the skin of a human body, and the percutaneous administration is safe and comfortable.
Owner:DONGHUA UNIV +1

Use of KPV tripeptide for dermatological disorders

InactiveUS6894028B2Preventing dermatological disorders and their associated symptomatolgyCosmetic preparationsHair removalDiseaseDermatological disorders
The present invention is directed to a prevention and treatment for dermatological disorders. One aspect of this invention involves a dermatological treatment comprising one or more polypeptides with an amino acid sequence including KPV (SEQ. ID. NO. 1), MEHFRWGKPV (SEQ. ID. NO. 2), HFRWGKPV (SEQ. ID. NO. 3), or SYSMEHFRWGKPV (SEQ. ID. NO. 4) for the treatment and prevention of dermatological disorders. The polypeptides are at a level to effectively treat the cutaneous inflammation and are carried by a carrier. The one or more polypeptides can also be a dimer formed from any of the amino acid sequence above.
Owner:MSH BIOPHARMA

Methods of use of compounds which inhibit the stem cell signaling pathway

This invention provides a method of preventing or treating in a subject contact dermatitis which comprises administering to the subject an amount of a compound capable of inhibiting the stem cell factor signaling pathway effective to prevent or treat contact dermatitis so as to thereby prevent or treat contact dermatitis in the subject. This invention also provides a methods of preventing or treating in a subject hyperpigmentation, asthma, cutaneous inflammation, anaphylaxis and bronchospasm, mastocytosis, tumors which express activated kit, and conception.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Methods for inhibiting cutaneous inflammation and hyperpigmentation

This invention provides a method of preventing or treating in a subject contact dermatitis which comprises administering to the subject an amount of a compound capable of inhibiting the stem cell factor signaling pathway effective to prevent or treat contact dermatitis so as to thereby prevent or treat contact dermatitis in the subject. This invention also provides a method of preventing or treating in a subject hyperpigmentation, asthma, cutaneous inflammation, anaphylaxis and bronchospasm, mastocytosis, tumors which express activated kit, and conception.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Multi-effect moisturizing and softening composition

The invention belongs to the field of daily chemical industry, especially relates to a daily skin care product and particularly relates to a multi-effect moisturizing and softening composition which can be used for regularizing skin, maintaining the water balance of skin, curing inflamed skin and erythema phenomena, prompting skin regeneration, refreshing and the like. The multi-effect moisturizing and softening composition comprises the following ingredients: oat glucan, bean collagen, aloe extract, microcapsule-coated ultraviolet absorbent, phytosterols, hydrogenated rosin glycerin ester, jojoba oil, natural squalane, siloxane, a natural an emulsifier, a water-phase thickener, a chelating agent, Ethylhexylglycerin, pentylene glycol, phenoxyethanol and water. The invention designs a temperate and multi-effect and high plant-content multi-effect moisturizing and softening composition through reasonably using and matching all ingredients. The multi-effect moisturizing and softening composition mainly aims at erythema, inflammation, crack, scratch and other problems, has the effects of moisturizing, softening, moisturizing, prompting skin regeneration, refreshing and the like, thus being an necessary daily caring and traveling skincare product.
Owner:OPAL COSMETICS HUIZHOU

Sunburn treatment and sunburn prevention method

The present invention is directed to a treatment for sunburn and a method for preventing sunburn. One aspect of this invention involves a sunburn treatment comprising one or more polypeptides with an amino acid sequence including KPV (SEQ. ID. NO. 1), MEHFRWG (SEQ. ID. NO. 2), HFRWGKPV (SEQ. ID. NO. 3), or SYSMEHFRWGKPV (SEQ. ID. NO. 4) for the treatment of the cutaneous inflammation caused by exposure to ultraviolet radiation. The polypeptides are at a level to effectively treat the cutaneous inflammation and are carried by a carrier. The one or more polypeptides can also be a dimer formed from any of the amino acid sequence above. In one preferred embodiment of the invention, the one or more polypeptides are used to prevent sunburn. In another preferred embodiment, the one or more polypeptides are dissolved in a carrier. In another preferred embodiment, the carrier includes aloe vera and lidocaine hydrochloride. In another preferred embodiment of the invention, the one or more polypeptides are dissolved in a liquid that is associated with an absorbent material for application to sunburned skin.
Owner:LIPTON JAMES M

Testing method for skin inflammation or irritation and kit

A non-invasive, in vivo method for measuring sub-clinical or clinical inflammation or irritation of mammalian skin from exposure of the skin to a topical skin care product, exposure to an external aggression or combinations thereof is disclosed. In one embodiment, the method includes the steps of collecting eicosanoid from the skin using a non-invasive collection device and analyzing levels of eicosanoid collected from the skin. A kit for measuring a marker of skin irritation or inflammation is also disclosed. The kit includes a non-invasive collection device for collecting secretions from the skin surface, and an immunoassay for measuring level of eicosanoid in the secretions.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES

Herbal composition for treatment of arthritic disorders, skin inflammatory disorders and pain

The present invention provides a method for treating arthritic disorders, skin inflammatory disorders and pain, comprising administering to a subject an extract of Andrographis paniculata Nees, and also provides a herbal composition used therefor that comprises the extract of Andrographis paniculata Nees.
Owner:云南白药中草药科技有限公司

Compositions and methods for treatment of pediatric pain

Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain treated by the disclosed methods may be of a type caused by inflammation induced mechanical and / or thermal hypersensitivity, and may include, for example, a pain type resulting from one or more conditions selected from peripheral injury pain, post-operative pain, cutaneous inflammation, cutaneous incision, muscle incision, or chronic pain. Disease states in which the disclosed methods may be used include fibromyalgia, sickle cell anemia, epidermolysis bullosa, erythromelalgia, complex regional pain syndrome, or generalized muscle pain.
Owner:CHILDRENS HOSPITAL MEDICAL CENT CINCINNATI

Medicine for treating acne

The invention discloses a medicine for treating acne, which is used for solving the problems that western medicine treatment is long in process, large in side effect and apt to reoccur and is prepared by fructus forsythiae, honeysuckle, Chinese violet, golden cypress, Sargassum, Sargent gloryvine, astragali radix, root of common peony and fructus kochiae. The medicine is used for treating acne, can reduce sebum secretion of sebaceous glands, restrains growth of bacteria in folliculus pili, reduces cutaneous inflammation reaction, promotes absorbing and diffusion of red and swollen nodules of folliculus pili portions, and achieves satisfied curative effects clinically. The medicine for treating acne is rigorous in compatibility of medicines, scientific, reasonable, low in cost, good in curative rate, short in course of treatment, convenient to use and not apt to reoccur and can be used for treating acne.
Owner:王爱英 +2

Medicinal fibre used for treating cutaneous inflammation and pain, preparation and application thereof

The invention relates to medicinal fibre used for treating cutaneous inflammation and pain, which comprises the components of cellulose acetate nano fibre, a ketoprofen ester precursor medicine and a medicinal percutaneous sorbefacient, wherein the ketoprofen ester precursor medicine accounts for 0.1-30% of the total weight of the fibre, the medicinal percutaneous sorbefacient accounts for 0.1-10% of the total weight of the fibre, and the cellulose acetate nano fibre accounts for 1-99% of the total weight of the fibre; the preparation of the medicinal fibre comprises the following steps: dissolving the ketoprofen ester precursor medicine, the medicinal percutaneous sorbefacient and the cellulose acetate into an organic solvent to prepare spinning liquid and then spinning to prepare the required medicinal fibre. The medicinal fibre has the effect of treating cutaneous inflammation and pain, has simple preparation method, convenient source of the raw materials and low cost, is friendly to the environment and is suitable for industrialized production; the fibre can be prepared into medicine-carrying clothings or other fabrics which directly contact with the skin of a human body, and the percutaneous administration is safe and comfortable.
Owner:DONGHUA UNIV +1

rhTSG6-FNIII-C fusion protein and application thereof in skin care composition and preparation method of the rhTSG6-FNIII-C fusion protein

The invention relates to the technical field of cosmetics, and discloses an rhTSG6-FNIII-C fusion protein, an application of the rhTSG6-FNIII-C fusion protein in a skin care composition and a preparation method of the rhTSG6-FNIII-C fusion protein. The rhTSG6-FNIII-C fusion protein is prepared through a genetic engineering prokaryotic expression technology. The specific method comprises the following steps: carrying out codon optimization on a gene sequence of SEQ ID NO: 1; constructing a recombinant expression vector and transforming; inducing and expressing the recombinant Escherichia coli; and separating and purifying an expression product, so that the rhTSG6-FNIII-C fusion protein is prepared. The skin care composition has various dosage forms, such as an aqueous solution, an ointment, a suppository, a cream and a mask, and has good skin care effects of improving skin wrinkles, keeping skin elasticity, reducing skin inflammation and allergy risks and the like, so that the skin care composition can be applied to the field of functional cosmetics or medical cosmetology.
Owner:WUHU TIANMING BIOTECH CO LTD

Stoma skin protective agent and preparation method thereof

The invention relates to a stoma skin protective agent and a preparation method thereof, chitosan is fully dissolved in water, chitosan is used as a hydrogel matrix, hydrogel is obtained by using chitosan with molecular weight of 25000g / mol to 150000g / mol and deacetylation grade higher than 85%, and the stoma skin protective agent has better antibacterial effect compared with many hydrogel such asPVA and PVP hydrogel on the market; in order to improve the properties of the hydrogel, purslane and at least one preservative are added, so that the antibacterial and anti-inflammatory effects are further improved; meanwhile, the panthenol is added and interacts with other components, so that the damaged skin can be repaired, and the generation of new cells is accelerated. The protective agent disclosed by the invention is good in treatment effect, can effectively relieve skin inflammation of a stoma patient, and particularly can effectively help healing when the skin of the stoma patient isulcerated.
Owner:湖北省亨德利医疗器械有限公司

Small Peptides And Methods For Inhibiting The Mucous Release Into Airways

InactiveUS20080214475A1AntipyreticDigestive systemSmall peptideAntigen challenge
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
Owner:MOWYCAL LENDING

Small Peptides And Methods For Inhibiting The Migration Of T-Cells

InactiveUS20080214477A1AntipyreticAnalgesicsSmall peptideT cell migration
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
Owner:HOUCK JOHN C +2

Method for anti-inflammation of skin and promoting keratinocyte proliferation

The present invention relates to new application of phytoextraction, especially to a method for anti-inflammation of skin and promoting keratinocyte proliferation by adopting the abstract of wedelia trilobata. The method comprises the steps of: adopting an extraction process to extract a lot of efficient substances (such as phenolic acids and diterpenes) of the wedelia trilobata, wherein the efficient substances have the functions of keratinocyte rapid updating and hyperplasia and anti-inflammation of skin, so that skin is prevent from being dirty by isolated from the outside, and the protection of the skin is improved.
Owner:TCI CO LTD

A tripeptide anti-allergic essence

The invention relates to the technical field of cosmetics and in particular discloses a tripeptide anti-allergy essence. The three-peptide anti-allergy essence comprises the following effective components in percentage by weight: 0.5 to 2 percent of Corallina officinalis extract; 1 to 3 percent of yeast skin whitening agent, 0.5 to 3 percent of honey extract, 0.3 to 3 percent of purslane extract and 0.3 to 5 percent of bradykinin solution. Since the tripeptide anti-allergy essence contains the relieving peptide solution, the production of TNF-alpha can be interfered, angioneurotic edema is reduced and cutaneous inflammation reaction is fundamentally and effectively reduced.
Owner:SANJIU JUNDA BIOTECH CO LTD GUANGDONG PROVINCE

Small peptides and methods for treatment of asthma and inflammation

InactiveCN1341026ASenses disorderDigestive systemIncreased inflammatory responseCell membrane
Methods for treating allergies, cutaneous inflammation, arthritis, chronic obstruction pulmonary disease and treating chronic inflammatory bowel disease are described. Also described is a method for inhibiting the infiltration of eosinophils into airways of a patient, a method for inhibiting the mucous release into airways of a patient, a method for blocking lgE activation of a lymphocyte, a method for stabillizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an lgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Try-Phe, Phe-Phe and Phe-Tyr.
Owner:HISTATEK

Composition for skin permeation of macromolecular drugs

The present invention provides a composition for transdermally permeating a macromolecular drug wherein the composition comprises an extract of a plant causing a skin inflammatory response, which extract can be used to prepare a composition for transdermally permeating a macromolecular drug, forming a transdermal drug delivery system. The composition can comprise a vasodilator, so as to improve the efficacy of the macromolecular drug penetrating into the blood through the skin.
Owner:傅柏舜 +3

Peptides having inhibitory activity on neuronal exocytosis

The invention relates to peptides capable of inhibiting neuronal exocytosis and to products comprising such peptides, in particular pharmaceutical and cosmetic products useful for ameliorating skin conditions, disorders and / or diseases mediated by neuronal exocytosis, such as wrinkles, excessive perspiration, pruritus, cutaneous inflammation, dermatitis, atopia, psoriasis, vascular hyperreactivity, rosacea, acne, hair growth, wound healing, calluses, warts, or sensitive skin conditions, such as ulcers and lesions on the skin.
Owner:AZIENDE CHIMHE RIUNITE ANGELINI FRANCESCO A C R A F

Methods and pharmaceutical composition reducing skin inflammation

The skin is one of first lines of defense against external threats. Tissue-resident macrophages have pivotal functions in tissue-barrier integrity and homeostasis. Upon skin inflammation, a functional crosstalk between the sensory nervous system and tissue-resident immune cells can regulate cutaneous immune responses. However, depending on the pathological context, sensory neurons display pro- or anti-inflammatory regulatory properties. Here the inventors identify, in a model of ultraviolet (UV)-induced skin N damage, a regulatory role for type C low-threshold mechanoreceptor (C-LTMR) sensory neurons on the dynamic of dermal macrophage replacement by inflammatory monocytes through the neuropeptide TAFA4. Tafa4-KO mice present an unresolved fibrotic dermis after UV irradiation. Increased fibrotic score correlates with the upstream persistency of inflammatory monocytes and their MHC-II+ macrophage progeny. Bone marrow chimera revealed that inflammatory monocyte differentiation towards CD206+ dermal macrophage is increased in Tafa4KO recipient. Finally, intradermal injection of TAFA4 at the site of UV irradiation reduces inflammatory monocytes accumulation and skin inflammation in Tafa4-KO mice. The results provide new insight about tissue-resident macrophages dynamic during the resolution of skin fibrosis and thus renders credible the use of TAFA4 for the treatment of skin inflammation.
Owner:INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM) +2

Traditional Chinese medicine capsule for treating acne

The invention discloses a traditional Chinese medicine capsule for treating acne. The traditional Chinese medicine capsule for treating the acne is prepared from, by weight, 10-15 parts of angelica sinensis, 5-8 parts of ricepaper pith, 3-5 parts of asarum sieboldii, 8-12 parts of cassia twig, 5-7 parts of raw radix paeoniae alba, 4-6 parts of honey-fried licorice roots, 3-7 parts of evodia rutaecarpa, 8-10 parts of leonurus artemisia, 10-12 parts of semen coicis, 1-3 parts of stir-baked squama manitis and 8-10 parts of spina gleditsiae. According to the theory of traditional Chinese medicine, the traditional Chinese medicine capsule for treating the acne is capable of clearing heat, removing toxicity, drying and removing dampness, softening hardness to dissipate stagnation, tonifying qi and expelling pus. When being used for treating the acne, the traditional Chinese medicine capsule for treating the acne is capable of reducing sebum secretion of the sebaceous gland, inhibiting growth of bacteria in hair follicles, alleviating cutaneous inflammation reaction and promoting absorption and dissipation of red and swollen nodules in the hair follicle part, thereby being good in clinical effect.
Owner:赵丛旭
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