36 results about "Cutaneous inflammation" patented technology

The present invention is directed to a prevention and treatment for dermatological disorders. One aspect of this invention involves a dermatological treatment comprising one or more polypeptides with an amino acid sequence including KPV (SEQ. ID. NO. 1), MEHFRWGKPV (SEQ. ID. NO. 2), HFRWGKPV (SEQ. ID. NO. 3), or SYSMEHFRWGKPV (SEQ. ID. NO. 4) for the treatment and prevention of dermatological disorders. The polypeptides are at a level to effectively treat the cutaneous inflammation and are carried by a carrier. The one or more polypeptides can also be a dimer formed from any of the amino acid sequence above.

This invention provides a method of preventing or treating in a subject contact dermatitis which comprises administering to the subject an amount of a compound capable of inhibiting the stem cell factor signaling pathway effective to prevent or treat contact dermatitis so as to thereby prevent or treat contact dermatitis in the subject. This invention also provides a methods of preventing or treating in a subject hyperpigmentation, asthma, cutaneous inflammation, anaphylaxis and bronchospasm, mastocytosis, tumors which express activated kit, and conception.

The present invention relates to a composition having enhanced anti-inflammatory properties and to a method for inhibiting inflammation in biological tissue, including but not limited to skin. Skin inflammation includes any undesirable effect produced in or on the surface of skin, including but not limited to irritation, redness, swelling, local temperature elevation, fissures, desquamation, itch, pain, sensitivity, abrasion, discoloration, and bleeding or the like, and combinations thereof. The invention demonstrates that certain plant fractions, such as the serum fractions of Camellia sinensis (Recentia® CS), Citrus limon (Recentia® CL), and Trifolium pratense (Recentia® TP), can be effectively utilized in various products to inhibit inflammation of biological tissue, including but not limited to skin. In one embodiment, said plant fractions have not undergone any significant fermentation.

The present invention provides a method for treating arthritic disorders, skin inflammatory disorders and pain, comprising administering to a subject an extract of Andrographis paniculata Nees, and also provides a herbal composition used therefor that comprises the extract of Andrographis paniculata Nees.

Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain treated by the disclosed methods may be of a type caused by inflammation induced mechanical and / or thermal hypersensitivity, and may include, for example, a pain type resulting from one or more conditions selected from peripheral injury pain, post-operative pain, cutaneous inflammation, cutaneous incision, muscle incision, or chronic pain. Disease states in which the disclosed methods may be used include fibromyalgia, sickle cell anemia, epidermolysis bullosa, erythromelalgia, complex regional pain syndrome, or generalized muscle pain.

The invention relates to medicinal fibre used for treating cutaneous inflammation and pain, which comprises the components of cellulose acetate nano fibre, a ketoprofen ester precursor medicine and a medicinal percutaneous sorbefacient, wherein the ketoprofen ester precursor medicine accounts for 0.1-30% of the total weight of the fibre, the medicinal percutaneous sorbefacient accounts for 0.1-10% of the total weight of the fibre, and the cellulose acetate nano fibre accounts for 1-99% of the total weight of the fibre; the preparation of the medicinal fibre comprises the following steps: dissolving the ketoprofen ester precursor medicine, the medicinal percutaneous sorbefacient and the cellulose acetate into an organic solvent to prepare spinning liquid and then spinning to prepare the required medicinal fibre. The medicinal fibre has the effect of treating cutaneous inflammation and pain, has simple preparation method, convenient source of the raw materials and low cost, is friendly to the environment and is suitable for industrialized production; the fibre can be prepared into medicine-carrying clothings or other fabrics which directly contact with the skin of a human body, and the percutaneous administration is safe and comfortable.

The present invention relates to the use of the water fragrant edge extract, especially the use of the water fragrant edge extract for reducing skin inflammation caused by keratinocyte irradiation with ultraviolet light and promoting skin keratin metabolism. The water fragrant edge extract is obtained by extracting water fragrant edge with a solvent of water, alcohol, or alcohol-water mixture, which can reduce skin keratinocyte inflammation caused by ultraviolet light irradiation, promote skin keratin metabolism and improve skin texture, Pore ​​size and reduced melanin content.

Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.

Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, methods for blocking IgE activation and for stabilizing the cell membrane of lymphocytes, mast cells, basophils, macrophages, monocytes, eosinophils, neutrophils, and the like, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.

Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.

The present invention relates to new application of phytoextraction, especially to a method for anti-inflammation of skin and promoting keratinocyte proliferation by adopting the abstract of wedelia trilobata. The method comprises the steps of: adopting an extraction process to extract a lot of efficient substances (such as phenolic acids and diterpenes) of the wedelia trilobata, wherein the efficient substances have the functions of keratinocyte rapid updating and hyperplasia and anti-inflammation of skin, so that skin is prevent from being dirty by isolated from the outside, and the protection of the skin is improved.

The invention belongs to the field of daily chemical industry, especially relates to a daily skin care product and particularly relates to a multi-effect moisturizing and softening composition which can be used for regularizing skin, maintaining the water balance of skin, curing inflamed skin and erythema phenomena, prompting skin regeneration, refreshing and the like. The multi-effect moisturizing and softening composition comprises the following ingredients: oat glucan, bean collagen, aloe extract, microcapsule-coated ultraviolet absorbent, phytosterols, hydrogenated rosin glycerin ester, jojoba oil, natural squalane, siloxane, a natural an emulsifier, a water-phase thickener, a chelating agent, Ethylhexylglycerin, pentylene glycol, phenoxyethanol and water. The invention designs a temperate and multi-effect and high plant-content multi-effect moisturizing and softening composition through reasonably using and matching all ingredients. The multi-effect moisturizing and softening composition mainly aims at erythema, inflammation, crack, scratch and other problems, has the effects of moisturizing, softening, moisturizing, prompting skin regeneration, refreshing and the like, thus being an necessary daily caring and traveling skincare product.

Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain treated by the disclosed methods may be of a type caused by inflammation induced mechanical and / or thermal hypersensitivity, and may include, for example, a pain type resulting from one or more conditions selected from peripheral injury pain, post-operative pain, cutaneous inflammation, cutaneous incision, muscle incision, or chronic pain. Disease states in which the disclosed methods may be used include fibromyalgia, sickle cell anemia, epidermolysis bullosa, erythromelalgia, complex regional pain syndrome, or generalized muscle pain.

Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.

The invention relates to the technical field of cosmetics, and discloses a rhTSG6-FNIII1-C fusion protein, its application in skin care composition and its preparation method. The rhTSG6-FNⅢ1-C fusion protein is prepared by genetic engineering prokaryotic expression technology, and the specific method includes: codon optimization of the gene sequence of SEQ ID NO:1; construction of a recombinant expression vector and transformation; induction of recombinant Escherichia coli and expression; the expression product is separated and purified to prepare rhTSG6‑FNⅢ1‑C fusion protein. The skin care composition of the present invention has multiple dosage forms, such as aqueous solution, ointment, suppository, cream and facial mask, and has good skin care effects such as improving skin wrinkles and maintaining skin elasticity, reducing skin inflammation and allergy risks, and so on. It is used in the field of functional cosmetics or medical cosmetology.