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In chemistry, a diamino acid, also called a diamino carboxylic acid, is a molecule containing at least one carboxyl and two amine functional groups. Diamino acids belong to the class of amino acids.
N-terminal region of a group b streptococcus surface protein as a carrier for the capsular polysaccharide
PCT designated stageWO2026109640A1Bacterial antigen ingredientsAntibody mimetics/scaffoldsDiamino acidStreptococcus infection
An immunogenic complex comprising i) an amino acid sequence of an N-terminal region of a group B Streptococcus surface protein selected from the group consisting of: a first amino acid sequence having at least 98%, such as 99%, identity to SEQ ID NO: 16 and a length of 172 amino acids to 178 amino acids; a second amino acid sequence having at least 98%, such as 99%, identity to SEQ ID NO: 18 and a length of 167 amino acids to 173 amino acids; and a third amino acid sequence consisting of SEQ ID NO: 20; and ii) a capsular polysaccharide, is provided. An immunogenic product, a vaccine, and the immunogenic complex, the immunogenic product or the vaccine for use in a method of preventing or treating a group B Streptococcus infection, are also provided.
Owner:MINERVAX