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Vaginitis lotion preparation method

A technology of vaginitis and lotion, which is applied in the field of drugs for the treatment of common gynecological diseases, can solve the problems of verrucous hyperplasia, ineffective antipruritic effect, and polluted underwear, and achieves small adverse reactions, good insecticidal and bactericidal effects, and safe reliable effect

Active Publication Date: 2010-01-20
合肥华威药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines are commonly used, but the antipruritic effect is not obvious, and some can also cause verrucous hyperplasia. Because the medicine liquid is dark in color, it will also pollute the underwear

Method used

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  • Vaginitis lotion preparation method
  • Vaginitis lotion preparation method
  • Vaginitis lotion preparation method

Examples

Experimental program
Comparison scheme
Effect test

no. 1 example

[0024] Take the following prescription:

[0025] 50g flavescens, 50g cork, 15g prickly ash, 0.5g borneol, 25g cnidium, 25g white fresh skin, 0.5g menthol, 0.5g domiphene.

[0026] Prepare the treatment vaginitis lotion according to the prescription of above-mentioned component by following steps:

[0027] 1) Soak 25g of Fructus Cnidii and 15g of Zanthoxylum bungeanum in 20 times the weight of water for 1 hour, then distill for 5 hours to collect the volatile oil, add 5ml of Tween-80 to grind it into medicinal residues, and collect the distilled aqueous solution separately;

[0028] 2) Merge the medicinal dregs with 50g of Sophora flavescens, 50g of Phellodendron Phellodendri and 25g of white fresh skin, put them in a multifunctional extraction tank, add 12 times the weight of water to soak for 1 hour, decoct for 1 hour, and then use 100 mesh filter;

[0029] 3) Decoct the dregs decocted in step 2) with 10 times the weight of water for 2 times, 1 hour each time, filter the de...

no. 2 example

[0035] Take the following prescription:

[0036] Sophora flavescens 70g, Phellodendron 70g, Chinese prickly ash 25g, borneol 2g, cnidium 35g, white fresh skin 35g, menthol 2g, domifene 2g.

[0037] Prepare the treatment vaginitis lotion according to the prescription of above-mentioned component by following steps:

[0038] 1) Soak 35g of Fructus Cnidii and 25g of Zanthoxylum bungeanum in 20 times the weight of water for 1 hour, then distill for 5 hours to collect the volatile oil, add 5ml of Tween-80 to grind it into medicinal residues, and collect the distilled aqueous solution separately;

[0039] 2) Merge the medicinal dregs with 70g of Sophora flavescens, 70g of Phellodendron Phellodendri and 35g of white fresh skin, put them in a multi-functional extraction tank, add 12 times the weight of water to soak for 1 hour, decoct for 1 hour and then use 100 mesh filter;

[0040] 3) Decoct the dregs decocted in step 2) with 10 times the weight of water for 2 times, 1 hour each t...

no. 3 example

[0045] Preferably, the following prescriptions are taken:

[0046] Sophora flavescens 60g, Phellodendron 60g, Zanthoxylum bungeanum 20g, Borneol 1g, Cnidium 30g, White fresh skin 30g, Menthol 1g, Domiphene 1g.

[0047] Prepare the treatment vaginitis lotion according to the prescription of above-mentioned component by following steps:

[0048] 1) Soak 30g of Fructus Cnidii and 20g of Zanthoxylum bungeanum in 20 times the weight of water for 1 hour, then distill for 5 hours to collect the volatile oil, add 5ml of Tween-80 to grind it into medicinal residues, and collect the distilled aqueous solution separately;

[0049] 2) The dregs are combined with 60g of Sophorae flavescens, 60g of Phellodendron Phellodendri and 30g of white fresh skin, put in a multi-functional extraction tank, add 12 times the weight of water to soak for 1 hour, decoct for 1 hour, and then use 100 mesh sieve filter;

[0050] 3) Decoct the dregs decocted in step 2) with 10 times the weight of water for 2...

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Abstract

The invention discloses a lotion against itching, wherein each 1000ml of the lotion comprises flavescent sophora root 50-70g, yellow corktree bark 50-70g, Chinese prickly ash 15-25g, borneol 0.5-2g, cnidium fruit 25-35g, dittany bark 25-35g, menthol 0.5-2g, domiphen bromide 0.5-2g. The preparing process of the lotion comprises steps of immersing cnidium fruit and pricklyash peel with 20 times by weight of water, distilling and collecting volatile oil, charging 5ml of Tween-80, grinding into slag, gathering distilled aqueous solution, merging raw materials and charging 12 times by weight of water for immersion, grilling and filtering, charging 10 times by weight of water into drug dross, grilling twice, filtering the decoction liquid, merging the filter liquor, filtering and merging the filter liquor with distilled aqueous solution, obtaining extract through decompression and concentration, charging ethanol to content of 60%, homogenizing, stewing, extracting supernatant fluid, reclaiming ethanol till no alcohol smell is present, and diluting to 1000ml with water.

Description

technical field [0001] The invention relates to a preparation method of a medicine for treating common gynecological diseases-vaginitis treatment lotion, which belongs to the field of traditional Chinese medicines. Background technique [0002] Common gynecological diseases include vaginitis and genital itching. In recent years, due to the influence of multiple factors, the disease has a tendency to occur clinically, which seriously endangers the physical and mental health of women and affects their life, work and study. [0003] Although the treatment of western medicine takes effect quickly, long-term use is more irritating to the vaginal mucosa, and most women patients are not easy to accept, and often cannot persist after a period of use, causing the medicine to fail to achieve the expected curative effect. After oral administration of chemicals, the concentration of the drug reaching the local vagina is low, and a larger oral dose is required to kill bacteria and trich...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61K36/756A61K36/75A61K36/534A61K36/489A61K36/234A61K31/138A61K31/045A61P15/02A61P17/04
Inventor 李贵华
Owner 合肥华威药业有限公司
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