Furosemide orally taking solution and the application in supersonic inspection

An oral solution, the technology of furosemide, applied in the field of medicine, to meet the clinical needs, rapid onset and convenient administration

Inactive Publication Date: 2007-09-12
贾恩礼
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, furosemide tablets as fast urine tablets are therapeutic drugs. At present, there is no preparation specially used to rapidly fill the bladder to assist ultrasound examination and diagnosis in China.

Method used

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  • Furosemide orally taking solution and the application in supersonic inspection

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0039] Composition: 10mg of furosemide is included in every 100ml of liquid medicine.

[0040] Preparation method: add furosemide to distilled water, gradually add sodium hydroxide solution while stirring, to make the pH value 10, and continue to stir until furosemide is completely dissolved; slowly add hydrochloric acid solution, adjust the pH value of the solution to about 8.5; Sterilize at 120°C for 30 minutes and put it in a 200ml glass bottle.

specific Embodiment approach 2

[0041] Composition: Each 100ml liquid contains 25mg of furosemide.

[0042] Preparation method: add furosemide to distilled water, gradually add sodium hydroxide solution while stirring, make the pH value 9.5, and continue to stir until furosemide is completely dissolved; slowly add hydrochloric acid solution, adjust the pH value of the solution to about 9.0; Sterilize at 110°C for 40 minutes and put it in a 200ml glass bottle.

specific Embodiment approach 3

[0043] Composition: Each 100ml liquid contains 25mg of furosemide and 30mg of steviol glycoside.

[0044] Preparation method: add furosemide to distilled water, gradually add sodium hydroxide solution while stirring, make the pH value 9.5, and continue to stir until furosemide is completely dissolved; dissolve stevioside in distilled water; Mix evenly; slowly drop in hydrochloric acid solution, adjust the pH value of the solution to about 9.0; keep at 120°C, carry out sterilizing treatment for 35 minutes, and put it in a 300ml glass bottle.

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Abstract

The present invention is orally taken furosemide solution and its application in ultrasonic examination. Of the furosemide solution, each 100 ml contains furosemide in 10-30 mg. The orally taken furosemide solution is prepared through adding furosemide into distilled water, regulating pH value and other steps. The orally taken furosemide solution is applied in ultrasonic imaging examination, and can promote urination fast to fill bladder so as to obtain clear ultrasonic image.

Description

Technical field: [0001] The invention relates to the technical field of medicine, in particular to furosemide oral solution, and its application as an auxiliary ultrasonic examination for diseases of pelvic organs such as bladder, ureter, prostate, uterus and accessories. Background technique: [0002] Clinically, when performing ultrasonography on the viscera in the pelvis, a full bladder is required as a sound-transmitting window to form a good imaging condition. At present, the most commonly used method is the natural urination method, but patients need to drink a lot of water and have to wait for 1 to 2 hours or longer. Some patients can obtain poor quality ultrasound images through the natural urination method, and even cannot complete the ultrasound examination at one time. , Need to make an appointment again, causing a lot of trouble to the patient. [0003] Some medical units also use intramuscular injection of furosemide or inject normal saline into the bladder thr...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K49/00A61K31/341
Inventor 贾恩礼
Owner 贾恩礼
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