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Quality control method of Changyanning pills

A Changyanning Tablet and detection method technology, applied in the detection field of Changyanning Tablets, can solve problems such as drugs with no obvious advantages, achieve product quality control and avoid volatilization

Active Publication Date: 2010-11-17
江西康恩贝中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] From the perspective of domestic treatment, the main therapeutic drugs for gastrointestinal diseases are concentrated in gastric ulcers, digestive aids and gastric motility drugs, while there are relatively few therapeutic drugs for enteritis. According to clinical reports, traditional Chinese medicine occupies the leading role in the treatment of chronic enteritis. The main body, but many of them are white prescriptions, and no drugs with obvious advantages have been seen

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Dijin grass 950g, yellow hair ear grass 1333.33g, camphor root 950g, fennel 516.67g, maple leaves 516.67g.

[0023] Take 90g each of Dijincao and Pansyria, grind them into fine powder respectively, pass through a 100-mesh sieve, stir-fry Dijincao until it becomes light brown, mix it with Pansyria powder, and set aside; Eargrass, camphor tree roots, maple leaves, add water to decoct twice, add 9 times the amount of water each time, 2 hours each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.15 when measured at 80°C, and let it cool , mix with above-mentioned fine powder and starch 50g, dry, pulverize into fine powder, granulate, dry, get camphor 1g, dissolve with 95% ethanol, spray in the granule, magnesium stearate 2.2g, press into 1000 tablets, Coated, that is.

[0024] HPLC

[0025] Chromatographic conditions and system suitability test use octadecylsilane bonded silica gel as filler; methanol-0.05% phosphoric acid ...

Embodiment 2

[0030] Dijin grass 977.78g, yellow hair ear grass 293.33g, camphor root 977.78g, fennel 508.89g, maple leaves 508.89g.

[0031]Take 70g each of Dijincao and Lemongrass, crush them separately, pass through a 80-mesh sieve, stir-fry Dijincao until it becomes light brown, mix it with Lemongrass powder, and set aside; take the remaining part of the above-mentioned two medicinal materials and the remaining part of the above-mentioned two-flavored medicinal materials and the yellow hair ear, Camphor tree roots and maple leaves were decocted twice with 10 times the amount of water, the first time was 2.5 hours, the second time was 2 hours, filtered, the combined filtrates were concentrated under reduced pressure until the relative density measured at 80°C was 1.20, Let it cool, mix with the above-mentioned fine powder and 60g of dextrin, dry, pulverize, granulate, dry, take 1.5g of camphor oil, dilute with 95% ethanol, spray into the granules, add 3g of talcum powder, press into 1000 ...

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PUM

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Abstract

The invention discloses a method for preparing tablets for treating enteritis and its quality control method, wherein the tablets comprise creeping euphorbia 330-1120 parts, goldhair hedyotis herb 450-1530 parts, camphor root 330-1120 parts, nutgrass flatsedge rhizome 150-560 parts, maple leaves 150-560 parts and camphor 0.2-3 parts. The preparing process consists of disintegrating the raw materials, extracting with water, concentrating the water extract liquid at 80 Deg C. to a relative density of 1.05-1.35, granulating, drying and tabletting.

Description

technical field [0001] The invention relates to the field of Chinese herbal medicines, in particular to a detection method for Changyanning tablets for treating acute and chronic gastroenteritis. Background technique [0002] Irritable bowel syndrome (Irritable Bowel Syndrone, IBS) is the most common gastrointestinal dysfunction in clinical practice. Pathophysiological basis of psychosomatic disorders. The medical community generally believes that the prevalence of IBS in Western countries is relatively high, about 10-20%; the incidence of IBS in China and Western countries is relatively similar; in Southeast Asia or the Middle East, the prevalence is lower, and Singapore has only one. 2.3%, Iran is about 3-4%. In the United States, IBS has become the second leading cause of employee absenteeism, second only to the common cold, and the direct or indirect treatment market for IBS in the United States is currently estimated at approximately $30 billion. Seven active ingredi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/74A61K9/28A61P1/00A61P1/12G01N30/02G01N30/90A61K31/125
Inventor 余德发徐发红陈科茂刘永祥
Owner 江西康恩贝中药有限公司
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