Children's diarrhea-relieving granular formulation containing patchouli and bark of magnolia, and preparation method thereof

Abstract

The invention discloses an infant broad spectrum antidiarrheal granule and a preparation method thereof. The preparation method comprises the following steps: using water which is 6 to 10 times of the weight of crude medicines to soak patchouli, Magnolia officinalis, Atractylodes chinensis and dried orange peels for 0.5 to 1.5 hours first, performing distillation for 6 to 10 hours, and collecting volatile oil; collecting medicine juice and medicine dregs for standby; adding water which is 6 to 10 times of the weight of crude medicines into Poria coccus, Alisma orientale, Herba Plantaginis and maticated leaven for decoction; mixing a decocted fluid and the medicine juice, concentrating the mixture to obtain an extract, cooling the extract, adding ethanol for standing and filtration, reclaiming the ethanol, performing concentration until an extract is obtained, adding water for dissolution, shaking the mixture evenly, performing cold preservation and filtration on the mixture, performing concentration until a clear paste is obtained, and drying and crushing the clear paste; and uniformly mixing the volatile oil and a solubilizer, adding the mixture into dextrin for uniform stirring, adding powdered sugar and extract powder, performing granulation and screening, and obtaining the infant broad spectrum antidiarrheal granule. The preparation technology for the granule can extract various effective components in the crude medicines to the maximum degree on the premise of considering the efficiency and the cost, and obviously improves the medicine effect of the granule compared with the prior infant broad spectrum antidiarrheal oral liquid.

Description

technical field [0001] The invention relates to a granule preparation of a traditional Chinese medicine composition and a preparation method thereof, in particular to a Xiaoer Guangpu antidiarrheal granule, and also relates to a preparation method of the granule, which belongs to the field of traditional Chinese medicine. Background technique [0002] Xiaoer Guangpu Antidiarrheal Oral Liquid is made of eight raw materials including patchouli, atractylodes, Poria cocos, Alisma, Magnolia officinalis (made from ginger), plantain, tangerine peel and Liushenqu (stir-fried). , and the effect of transporting the spleen. It is used for diarrhea in children caused by dampness and spleen soil. Symptoms: Diarrhea, loose or watery stool, abdominal distension, abdominal pain, anorexia, vomiting, or fever, pale tongue with white and greasy fur, rotavirus enteritis and non-infectious diarrhea with the above syndromes. [0003] The prescription of Xiaoer Guangpu Antidiarrheal Oral Liquid ...

AI Technical Summary

Problems solved by technology

[0005] It can be seen from the above that the existing preparation process of Xiaoer Guangpu Antidiarrheal Oral Liquid does not have the specific process parameters for extracting volatile oils from Patchouli, Ma

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