Method for preparing standard substance for detecting antibiotics in cosmetics

Abstract

The invention relates to a method for preparing a standard substance for detecting antibiotics in cosmetics. The standard substance is formed by mixing aqueous solution of the antibiotics or solution of propylene glycol and cosmetic cream, wherein the cosmetic cream comprises the following components in percentage by weight: 73 to 78 percent of de-ionized water, 3 to 3.5 percent of propylene glycol and 0.2 to 0.25 percent of carbomer in phase A, 4.5 to 5 percent of stearate, 3 to 4 percent of cetyl alcohol and stearyl alcohol and 10 to 14 percent of 26# white oil in phase B and 1.2 to 1.25 percent of phenoxyethanol and ethylhexylglycerin in phase C; and the concentration of the antibiotics in the standard substance reaches 0.1g / 100mL. The method has the advantages that: the antibiotics and the cosmetic cream are mixed to form the standard substance for detecting the antibiotics such as minocycline hydrochloride, oxytetracycline dehydrate, tetracycline hydrochloride, chlortetracycline hydrochloride, doxycycline hydrochloride and chloramphenicol in the cosmetic; and the standard substance is the same as a sample of the cosmetic containing the antibiotics in the actual use; thus the detection of the antibiotics in the cosmetic conforms to the state of the actual application better and is more accurate.

Description

technical field [0001] The invention relates to the field of cosmetic testing, in particular to a method for preparing standard substances for testing antibiotics in cosmetics. Background technique [0002] The detection of antibiotics in cosmetics is one of the important guarantees for the safety of cosmetics. At present, direct compound detection methods are mostly used. However, in practical applications, after the antibiotics in cosmetics are mixed with the ingredients of the formula, the detection will be compared with the direct use of compounds. There are large differences in detection, which will affect the accuracy of detection. Compared with standard compounds, cosmetic standard substances not only have accurate measurement standards, but also have one or more sufficiently uniform and well-determined characteristic values, and have traceability of the value, which is very important for improving cosmetics production, The detection level of cosmetics inspection, th...

AI Technical Summary

Problems solved by technology

[0002] The detection of antibiotics in cosmetics is one of the important guarantees for the safety of cosmetics. At present, direct compound detection methods are mostly used. However, in practical applications, after the antibiotics in cosmetics are mixed with the ingredients of the formula, the detection will be compared with the direct use of compounds. There is a big difference in the detection, which will affect the accuracy of the detection

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