Oral care product and methods of use thereof

An oral care and composition technology, applied in the field of oral care compositions, can solve problems such as injury, dental fluorosis and the like

Inactive Publication Date: 2011-01-05
COLGATE PALMOLIVE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, young children can be harmed by overexposure to fluoride (for example, by swallowing large amounts of fluoridated toothpaste), leading to dental fluorosis in developing teeth, and while fluoride used in toothpaste has an excellent safety record, Some still prefer the amount of fluoride to be the absolute minimum for effectiveness

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0210] Example 1 - Effectiveness and Delivery of Fluoride in Arginine Formulations

[0211] A formulation was prepared using a commercial toothpaste containing 0.3% by weight of triclosan, 0.075% by weight of sodium fluoride, sodium lauryl sulfate and a copolymer of methyl vinyl ether and maleic anhydride (PVM / MA) , adding 0, 1%, 3% and 5% L-arginine hydrochloride (pH 7.0) to each formula respectively.

[0212] Incorporation of L-arginine in commercial formulations increases the amount of soluble fluoride available from the formulation. This enhanced delivery leads directly to improved delivery of the fluoride effect of the formulation.

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PUM

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Abstract

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form and a low dosage of fluoride and to methods of using such compositions.

Description

[0001] This application claims the benefit of U.S. Patent Application Serial No. 61 / 027,441, filed February 9, 2008, and also claims U.S. Patent Application Serial No. 61 / 027,442, filed February 9, 2008, and U.S. Patent Application Serial No. Claims to Patent Application Serial Nos. 61 / 027,432, 61 / 027,431, 61 / 027,420, and 61 / 027,435, the contents of which are incorporated herein by reference. field of invention [0002] The present invention relates to oral care compositions comprising basic amino acids in free or salt form and low doses of fluoride, and to methods of using these compositions. Background of the invention [0003] Arginine and other basic amino acids have been proposed for oral care and are believed to have significant benefits in combating cavity formation and tooth sensitivity. However, combining these basic amino acids with oral care benefit minerals such as fluoride and calcium to form oral care products with acceptable long-term stability has proven to b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/44A61K8/20A61Q11/00
CPCA61Q11/00A61K31/198A61K33/16A61K8/21A61K8/44A61K31/09A61P1/02A61K2300/00
Inventor R·科利R·罗宾逊R·萨利文D·库明斯
Owner COLGATE PALMOLIVE CO
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