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Two-dimensional visualization encryption method for genetic information based on iteration function

A technology of genetic information and iterative function, applied in the direction of genetic model, can solve the problem of inconvenient manual analysis and comparison, and achieve the effect of beautiful results and protection of personal privacy.

Inactive Publication Date: 2014-08-06
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although this kind of genetic information is accurate, it is not convenient for manual analysis and comparison, especially when many loci are involved.

Method used

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  • Two-dimensional visualization encryption method for genetic information based on iteration function
  • Two-dimensional visualization encryption method for genetic information based on iteration function
  • Two-dimensional visualization encryption method for genetic information based on iteration function

Examples

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Comparison scheme
Effect test

example 1

[0020] Example 1: Visualization of STR loci

[0021] The genetic information of individual a at 17 loci are:

[0022] Site name: D16S539; D7S820; D13S317; CSF1PO; TPOX; TH01; F13A01; FES; vWFA31; HPRTB; F13B; FABP; LPL; CYAR04; CD4; GPP3A09; ,11;11,10;12,9;12,9;11,8;9,8;6,3;11,11;17,16;13,13;10,10;10,9;12,10 ;11,7;7,7;6,6;11,10;

[0023] As shown in reference 1, when these sites are initialized according to the method described in the present invention, the visualization result is figure 1 . Then use rule 1 to iterate 100 times and rule 2 to iterate 100 times to get the final image, which contains 536*536 squares. Such as image 3 . This pattern contains all the genetic information of the individual in hidden state.

example 2

[0025] The SNP genetic information of individual A is as follows:

[0026] Site name:

[0027] rs7121845 rs1940094 rs1940092 rs472587 rs1789175 rs555867 rs6592199

[0028] rs6592202 rs1943707 rs7110559 rs1943696 rs1943701 rs1943705 rs4370960

[0029] rs1943699 rs3802893 rs876695 rs1943710 rs952201 rs1943715 rs2000815

[0030] rs1943725 rs1943733 rs957438 rs6592211 rs1227671 rs1940125 rs7111775

[0031] rs2155413 rs1073987 rs7108021

[0032] At each locus, the form of the individual SNP: (0 means low frequency SNP, 1 means common SNP)

[0033] Individual A:

[0034] 1,0,0,0,1,0,0,0,1,0,1,1,1,0,1,0,1,0,0,0,1,0,1,0,1, 0,1,1,1,0,1,1,0,0,1,1,0,0,1,0,1,1,1,1,0,0,1,0,1,0, 1,1,0,0,0,0,1,1,1,1,0,0

[0035] According to the method shown in 1, the grid is initialized for the data, and the state of the grid is set. The result is figure 2 . Use iteration 1 and iteration 2 described in 2 and 3 in sequence 100 times each to get the visualized results Figure 4 . This image conta...

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Abstract

The invention relates to a two-dimensional visualization encryption method for genetic information based on an iteration function. Individual genetic information comprises traditional STR (short tan-dem repeat) site information and numerous pieces of SNP (single nucleotide polymorphism) information. The genetic information is represented by small checks of different coordinates and different colours in a two-dimensional planer grid by mapping. The invention provides a method that the genetic information represented in the planer grid is iterated by an iterative function. In the iteration process, the original genetic information is concealed, patterns with a certain rule are obtained, and a visible encrypted individual 'genetic fingerprint' pattern is formed. The pattern is convenient to carry out difference comparison and can be used for aspects of individual biological feature identification, biological feature keys, genetic information visualization and the like.

Description

technical field [0001] The invention belongs to the technical field of information security and biological feature identification, and in particular relates to a two-dimensional visual encryption method of genetic information based on an iterative function. Background technique [0002] Everyone has two sets of chromosomes, which are important genetic information and also a biological characteristic that contains rich information. There are differences in the genetic information of different people, and these differences will be reflected in many different positions on the DNA molecule. Genetic information can be detected by PCR technology combined with gel electrophoresis, mass spectrometry, gene chip and other technologies, and the results are different types of experimental data. After these data are processed, for STR sites, it is usually represented by the number of repeats of short repeats (STR); for SNP sites, according to the genotype of its allele, 11, 10 or 00 can...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06N3/12
Inventor 吴晓明杜建强王旭李慧丽
Owner XI AN JIAOTONG UNIV
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