Pollen pini water extract for treating child sexual precocity, preparation method and use of pollen pini water extract

A technology of water extract and pine pollen is applied in the directions of medical raw materials, drug combinations, endocrine system diseases derived from gymnosperm subphylum, etc., and achieves the effects of low price, good absorption effect and preventive precocious puberty.

Active Publication Date: 2012-09-26
YANTAI NEW ERA HEALTH IND +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, people had a wrong understanding of pine pollen. Without the necessary research, they believed that taking pine pollen and its products was the culprit for the precocious puberty of children in my country. Almost all the experts in the country about the precocious puberty of children thought so, but they did not know that pine pollen It may become a good medicine for preventing and treating precocious puberty in our children

Method used

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  • Pollen pini water extract for treating child sexual precocity, preparation method and use of pollen pini water extract
  • Pollen pini water extract for treating child sexual precocity, preparation method and use of pollen pini water extract
  • Pollen pini water extract for treating child sexual precocity, preparation method and use of pollen pini water extract

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Experimental program
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Embodiment Construction

[0031] 1. Prepare the aqueous extract of gymnosperm pine pollen for treating precocious puberty in children:

[0032] 1. Sorting pine pollen: remove pine pollen impurities at room temperature.

[0033] 2. Wall-breaking treatment: the impurity-removed pine pollen is subjected to air-flow crushing and wall-breaking treatment for 10 to 20 minutes.

[0034] 3. Soaking and ultrasonic treatment: Soak the pine pollen after wall-breaking treatment with normal pressure and normal temperature water for 10-15 minutes, and then ultrasonic treatment for 20-40 minutes.

[0035] 4. Centrifuge to remove solid impurities, take the aqueous solution: centrifuge for 10-15 minutes in a refrigerated centrifuge with a rotating speed of 8000-10000 rpm, and take the supernatant.

[0036] 5. Ultrafiltration: Use 4000D molecular sieve ultrafiltration on the supernatant taken at an ambient temperature of 1-5°C to separate the pine pollen water extract with a molecular weight below 4000D, which is used t...

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Abstract

The invention provides a preparation method of a pollen pini water extract for treating child sexual precocity and use of the water extract, belonging to the technical field of process for extracting effective matters from pollen pini. The preparation method comprises the following steps of: performing wall breaking process to gymnosperm pollen pini through air current for 10 to 20 minutes; dipping the broken matters in water for 10 to 15 minutes at normal pressure and normal temperature; performing ultrasonic treatment for 20 to 40 minutes; removing solid impurities by a centrifugal method, taking supernatant fluid; super-filtering and separating the supernatant fluid by a molecular sieve under 1 to 5 DEG C; and obtaining the pollen pini soluble matter with molecular weight less than 4000D. The pollen pini extract can be used for preparing oral preparation for treating the children sexual precocity; the oral preparation is good in absorbing effect, low in cost, and capable of preventing the children sexual precocity; the pollen pini extract also can be used for preparing injection preparation for treating the children sexual precocity; and the injection preparation is quickly absorbed, and strong in treating pertinence.

Description

technical field [0001] The invention relates to the technical field of extracting effective substances from gymnosperms, especially from pine pollen. Background technique [0002] Precocious puberty refers to the significantly earlier age of sexual maturity in children, which is mainly manifested in the premature development of children's gonads (ie, testes in men and ovaries in women), early development of reproductive organs, and the appearance of secondary sexual characteristics. Medically, the age of precocious puberty is defined as before 8 years old for girls and 9 years old for boys, and the appearance of secondary sexual characteristics that do not correspond to age is called precocious puberty. Girls experience periodic vaginal bleeding, enlarged breasts, widened buttocks, pubic and armpit hair growth, menstrual cramps, etc., accompanied by physical development, such as height, weight, and bone growth. Before the age of 9, the boy had enlarged testicles and scrotum...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/15A61P5/24
Inventor 周斌刘志河石丽花叶满红王桐于建伟鞠东尹利端李明乔强
Owner YANTAI NEW ERA HEALTH IND
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