Method for quickly and automatically classifying particles and implementation device thereof

An automatic classification and particle technology, applied in the field of flow cytometry counting and analysis systems

Active Publication Date: 2012-01-04
DIRUI MEDICAL TECH CO LTD
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

This algorithm has a good classification effect for some samples with common characteristics, but the effect is poor for abnormal samples. At the same time, the algorithm is based on the premise of sacrificing certain efficiency.

Method used

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  • Method for quickly and automatically classifying particles and implementation device thereof
  • Method for quickly and automatically classifying particles and implementation device thereof
  • Method for quickly and automatically classifying particles and implementation device thereof

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Embodiment Construction

[0051] The specific embodiment of the present invention will be described in combination with the application of the present invention in a blood cell analyzer.

[0052] The blood cell analyzer can detect the number of white blood cells, red blood cells, platelets, hemoglobin and other parameters in the blood. For the detection of white blood cells, there are two independent channels for the detection of white blood cells. Lymphocytes (Lym), monocytes (Mono), eosinophils (Eos) and neutrophils (Neut) can be displayed on the same scatter plot and counted separately. On this scatter diagram, there are also ghost cells (Ghost). The specific implementation content of the present invention is to classify the above-mentioned 5 kinds of granular cells. by figure 1 The data shown in the scatter plot is the basic raw data. The specific implementation steps are as follows:

[0053] (1) Particle classification information is obtained by collecting the scattered light signal...

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Abstract

The invention provides a method for quickly and automatically classifying particles and an implementation device thereof, and belongs to a method for classifying the particles and counting the number by a particle detector. The method comprises the following steps of: forming a scatter diagram, filtering to obtain a projection histogram represented by two-dimensional vectors, dividing the particles twice, correcting parts of the divided scatter diagram, and counting the number of the particles in various areas. The invention has the advantages that: the particles are classified automatically, accurately and quickly, and the method has strong adaptability, practicability and stability for normal samples or abnormal samples.

Description

technical field [0001] The invention relates to a method and device for classifying and counting particles by a particle detector, which is used in the field of blood cell analysis and detection, and particularly relates to a flow cytometry counting and analysis system. Background technique [0002] The blood cell analyzer can detect the number of white blood cells, red blood cells, platelets, hemoglobin and other parameters in the blood and can classify the white blood cells. Among them, classifying white blood cells is its basic function. The blood cell analyzer plays a certain reference role in the discovery and diagnosis of some blood diseases, and is one of the indispensable instruments for clinical testing. At present, blood cell analyzers mainly use electrical impedance method or flow cytometry for counting and classification, and some instruments use both methods. [0003] Among them, flow cytometry (Flow Cytometry, FCM) is a technology for automatic cell analysis....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/10G06F17/30
Inventor 宋洁朱海波刘杨陈哲
Owner DIRUI MEDICAL TECH CO LTD
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