Application of shenxiong glucose injection to preparing medicine for treating pulmonary hypertension

A technology of Shenxiong glucose and pulmonary arterial hypertension is applied in the application field of preparing pulmonary arterial hypertension medicines, and can solve the problems of non-ideal normal reference value, pulmonary arterial hypertension and the like

Inactive Publication Date: 2012-10-03
GUIZHOU JINGFENG INJECTION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] 5. Pulmonary hypertension caused by unknown mechanism and (or) multiple mechanisms
[0014] At present, there is no ideal normal reference value for the test, so the changes in the absolute value of walking distance are used to reflect the changes in the condition of patients with pulmonary arterial hypertension

Method used

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  • Application of shenxiong glucose injection to preparing medicine for treating pulmonary hypertension
  • Application of shenxiong glucose injection to preparing medicine for treating pulmonary hypertension
  • Application of shenxiong glucose injection to preparing medicine for treating pulmonary hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The detection of patients with pulmonary hypertension before and after treatment with Shenxiong Glucose Injection.

[0023] 1. Conditions for test subjects to enter the group:

[0024] Patients with arterial hypertension aged 6-70 years;

[0025] Patients with clinically confirmed pulmonary hypertension;

[0026] Patients with chronic thrombotic pulmonary hypertension;

[0027] No treatment with prostacyclin drugs or endothelin receptor antagonists within 3 months

[0028] 2. Treatment plan

[0029] Fifty-one patients with pulmonary hypertension who met the criteria for enrollment were randomly selected clinically and treated with Shenxiong Glucose Injection. The intravenous injection was 200ml each time, once a day, and a course of treatment was 14 days.

[0030] 3. Analysis project

[0031] Pulmonary hypertension patients before and after treatment with pulmonary artery systolic pressure (sPAP), oxygen partial pressure (PO2), carbon dioxide partial pressure (PCO2) and 6-min walking...

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Abstract

The invention belongs to the field of medicines, and particularly relates to an application of shenxiong glucose injection to preparing a medicine for treating pulmonary hypertension. Clinically, the used amount of shenxiong glucose injection is 200ml for general intravenous injection, once for one day and 14 days for one treatment course. The application is characterized in that the systemic blood pressure (SBP), diastolic blood pressure (DBP), systolic pulmonary artery pressure (sPAP), partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2) and the condition of 6min walking-distance test of a patient with the pulmonary hypertension are monitored, and by contrast observation on all indexes before and after the patient with the pulmonary hypertension accepts the treatment with the shenxiong glucose injection, the shenxiong glucose injection has obvious inhibitory action on the pulmonary hypertension by injection. The shenxiong glucose injection can be used as an ideal medicine for treating the pulmonary hypertension disease.

Description

Technical field [0001] The invention relates to the field of medicinal chemistry. Specifically, the present invention relates to a new medical use of Shenxiong glucose injection, that is, the application of Shenxiong glucose injection in preparing pulmonary hypertension drugs. Background technique: [0002] Shenxiong Glucose Injection is a Chinese medicine monomer compound preparation, and its components are: Danshensu, Ligustrazine Hydrochloride, Glucose and Glycerin. After years of clinical observation and experimental research, the application range of Shenxiong Glucose Injection has been greatly expanded. The published and proven effects are: [0003] 1. The Shenxiong Glucose Injection disclosed in Chinese Patent ZL200410022286.X has a good effect on the treatment of coronary heart disease, angina pectoris, myocardial ischemia, myocardial infarction, stroke, etc. [0004] 2. The Shenxiong Glucose Injection disclosed in Chinese Patent ZL200410035816.4 has therapeutic and prevent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4965A61K9/08A61P9/12A61P11/00A61K31/192
Inventor 叶湘武罗丽黄小音韦鑫
Owner GUIZHOU JINGFENG INJECTION
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