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Plasticizer tracking biomarker, plasticizer tracking genetic chip, and plasticizer tracking biomarker confirmation method

A biological marker and gene chip technology, applied in biological testing, organic compound library, chemical library, etc., can solve the problems of carcinogenic risk, high toxicity, and no effective countermeasures by government agencies.

Inactive Publication Date: 2013-07-17
舍尔辛格
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

DEHP is 20 times more toxic than melamine, not only causing reproductive toxicity, but even carcinogenic
Unscrupulous operators add plasticizers, which will inevitably affect public health
[0004] Although these plasticizers that endanger human health have existed in food for a long time, due to the absence of this shocking incident and the indifference of the Chinese people to environmental poisons, the people and even government agencies have no An effective countermeasure

Method used

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  • Plasticizer tracking biomarker, plasticizer tracking genetic chip, and plasticizer tracking biomarker confirmation method

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Embodiment Construction

[0015] Before starting to describe the embodiments of the present invention, the background of the present invention will be explained in detail. The present invention utilizes the existing gene database to screen out suitable biomarkers (genes or proteins) in a specific way, and uses them as probes to make suitable gene chips.

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Abstract

The invention discloses a plasticizer tracking biomarker, a plasticizer tracking genetic chip, and a plasticizer tracking biomarker confirmation method. The biomarker found through the confirmation method is one or more of human gene / protein clusters composed of PPARG, CASP3, PPARA, NR1I2, ESR1, AR, CYP1B1, ABCB1, CYP1A1, VEGFA, ESR2, PPARD, LAMP3, BAX, BCL2, CDO1, CELSR2, CSNK1A1, CYP3A4, MAPK1, MAPK3, MYC, NCOA1, PAPSS1, PAPSS2, SUOX, SLC5A5, AKR1C1, IL4, INHA and PCNA, and is suitable for detecting that whether there is pollution of plasticizers, such as phthalate and the like, in a human body or not.

Description

technical field [0001] The present invention relates to a biomarker and its confirmation method, in particular to a biomarker and gene chip for tracking plasticizers and its confirmation method. Background technique [0002] The plasticizer incident (also known as plasticizer / plastic poison storm, plasticizer / plastic poison storm, etc.) is a series of food safety incidents that broke out in Taiwan at the end of May 2011. The incident was caused by the detection of plasticizers in some foods on the market, and it was found that some upstream raw material suppliers used cheap industrial plasticizers in the common legal food additive "clouding agent" to save costs. In addition to the originally disclosed beverage products, the scope of influence has also extended to cakes, bread and medicines. After the incident broke out, the relevant government agencies clearly stipulated that from June of the same year, if the relevant food had not completed self-inspection, all sales would...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68G01N33/68C40B40/06G06F19/10
Inventor 舍尔辛格
Owner 舍尔辛格
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