Automatic image alignment

An image, in-image technology, applied in the field of automatically aligning images, can solve problems such as impracticality, difficulty in finding matching points, and cumbersome process

Active Publication Date: 2013-09-25
SONY CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For very large images (e.g., 100k×100k), the process becomes tedious and impractical
Also, when the image is locally inspected at high resolution, the appearance between corresponding regions diverges rapidly, making it difficult to find matching points

Method used

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Embodiment Construction

[0023] Reference will now be made in detail to example embodiments, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.

[0024] The methods and systems disclosed herein have many practical applications. For example, exemplary embodiments can be used to automatically align large images of tissue samples stained with different methods. By identifying matching points and modeling local deformations through local transformations, the methods and systems disclosed herein enable simultaneous viewing of different resolutions and synchronize corresponding regions in the image. The methods and systems disclosed herein can be used not only for pathological diagnosis purposes, but also for aligning any images that are similar in overall appearance but contain local variations or differences, for example, satellite images of different perspectives of the sam...

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Abstract

The invention discloses automatic image alignment. A method for automatically aligning images includes (a) determining initial correspondent point features between a first image and a second image, (b) creating a triangular meshes for the images from the initial correspondent point features within the images, and (c) refining point correspondence between the first and second images based on affine transformation estimation using the triangular meshes. The method may also include (d) creating refined triangular meshes for the images from the point correspondence refined in (c), and (e) determining coordinate alignment within the areas of pairs of correspondent triangles in the refined triangular meshes through interpolation of affine transformation on the pairs of correspondent triangles.

Description

technical field [0001] The present disclosure relates to methods and systems for automatically aligning images (eg, images of tissue samples stained with different methods). Background technique [0002] Pathological diagnosis typically involves thin sections of tissue samples (eg, biopsies), placement of the sections on individual glass slides, and staining of the sections with different methods and reagents. For example, a tissue sample section can be stained with a hematoxylin and eosin (H&E) stain to visualize the histology of the sample, while an adjacent tissue sample section can be used for immunohistochemistry (IHC) with disease-specific antibodies. ) dye staining. Pathologists typically perform primary diagnosis on H&E stained samples, followed by IHC staining from the same biopsy block for verification and prognosis. [0003] With the trend toward digitization, specimen slides are often scanned as digital images (virtual slides) for later viewing on a monitor. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T3/00G06T1/00G06V10/426
CPCG06T2207/30024G06T7/33G06T2207/20072G06V20/695G06V10/426
Inventor 余良吟刘明昌
Owner SONY CORP
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