Portulaca oleracea oral liquid for treating non-alcoholic fatty liver and preparation method thereof

Abstract

The invention provides a portulaca oleracea oral liquid for treating non-alcoholic fatty liver and a preparation method thereof. The oral liquid is prepared from portulaca oleracea and salvia miltiorrhiza as main raw materials, and semen cassiae, crataegus pinnatifida and alisma orientalis by an extraction process. According to prevention and treatment of an animal model of non-alcoholic fatty liver, laboratory blood biochemical test results, liver tissue pathological and morphological examination, and analysis of action mechanism of the portulaca oleracea oral liquid in preventing and treating non-alcoholic fatty liver, through experiments, the portulaca oleracea oral liquid can remarkably reduce total cholesterol and triglyceride contents in serum of a non-alcoholic fatty liver mouse, and reduce the activities of alanine aminotransferase and aspartate aminotransferase; as being is in positive correlation with dose, the portulaca oleracea oral liquid has good therapeutic actions in improving blood lipid metabolism, resisting lipid peroxidation, protecting liver function, and so on.

Description

[0001] Technical field: [0002] The invention relates to a traditional Chinese medicine oral liquid for treating fatty liver, in particular to a purslane oral liquid for treating nonalcoholic fatty liver and a preparation method thereof. Background technique: [0003] Under the current trend of economic globalization, the number of non-alcoholic fatty liver patients in my country is rapidly increasing, and only middle-aged patients in Zhengzhou City account for about 15%. At present, the treatment of this disease mainly focuses on dieting, lipid-lowering, and liver protection. However, lipid-lowering western medicines have large side effects, greater damage to the liver, and poor efficacy. So looking for traditional Chinese medicine to treat this disease is the focus of attention today. [0004] Nonalcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by fat accumulation and steatosis in hepatic parenchymal cells without a history of exc...

AI Technical Summary

Problems solved by technology

[0006] The western medicine currently used clinically for the treatment of non-alcoholic fatty liver has a single effect, complicated medication, no definite curative effect, and many adverse reactions (such as insulin sensitizers Cardiovascular events can be induced; traditional liver cell-protecting drugs have only a single curative effect; lipid-lowering drugs can regulate lipid metabolism and reduce cardiovascular events, but they cannot avoid drug-induced liver damage. Western medicine is limited in the development and fibrosis of the liver

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