Inductive osteogenesis short-chain peptide, preparation method and application thereof

A short peptide, osteogenic technology, applied in the field of clinical medicine, can solve the problems of complex preparation process, low yield, high price, etc., and achieve the effects of broad market prospects, strong osteoinductive activity, and high osteoinductive activity.
CN103880928AInactive Publication Date: 2014-06-25η”˜ε°‘η£Š
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
η”˜ε°‘η£Š
Publication Date
2014-06-25
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention relates to an inductive osteogenesis short-chain peptide. A structure formula of the inductive osteogenesis short-chain peptide is shown as KIPKASSVPTELSAISTL. The inductive osteogenesis short-chain peptide has strong osteogenesis inducing activity and can be synthesized in a large scale at low cost. The invention overcomes the defect that current BMP-2 (Bone Morphogenetic Protein-2) production devices and preparation processes are very complicated, have long production cycle, low productivity, a small possibility of producing in large scale and excessively high cost; the inductive osteogenesis short-chain peptide is wide in market prospect.
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Description

technical field

[0001] The invention belongs to the field of clinical medicine, and more specifically relates to an osteogenesis-inducing short peptide, its preparation method and its application in the preparation of medicines for promoting bone regeneration and bone defect repair. Background technique

[0002] Chinese society is gradually entering an aging society, and the incidence of middle-aged and elderly orthopedic diseases will also increase significantly. Therefore, China will also face a huge demand for artificial bone graft materials. According to statistics, there are 15 million patients with limb insecurity in China, and 3 million people have amputated their limbs due to lack of reconstruction technology and materials. There are nearly 3.5 million patients with bone defects and bone injuries in the country every year. Calculated on the basis of 400,000 operations per year, the entire Chinese bone graft material The market size of China will also reach a scale of...

Claims

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