Cream preparation with high oil phase content and no emulsifier and preparation method of cream preparation

Abstract

The invention discloses a cream preparation with high oil phase content and no emulsifier and a preparation method of the cream preparation. The cream preparation comprises the following components: components A: 0.30-0.40% of acrylic acid (acrylate) C10-30 alkanol acrylate cross-linked polymer, 0.10-0.20% of xanthan gum and 0.10-0.30% of sodium hyaluronate; components B: 3.0-5.0% of pentanediol, 3.0-8.0% of glycerol polyether-26 and 0.5-1.0% of sorbitan octoate; components C: 15.0%-20.0% of squalane, 10.0%-20.0% of neopentyl glycol dioctoate / dicaprate, 5.0%-10.0% of simmondsia chinensis seed oil; components D: 3.0-5.0% of glycerol and 30.1-60.0% of water; based on 100% in total, the components A account for 0.5-0.9%, the components B account for 6.5-14.0%, components C account for 30.0-50.0% and components D account for 35.1-63.0%. The cream preparation disclosed by the invention can be used for emulsifying 30%-50% of the oil phase content, substitutes about 5% of the conventional emulsifier and about 8% of the natural emulsifier, and avoids potential skin irritation risks caused by using emulsifier largely.

Description

technical field [0001] The invention belongs to the fields of medicine, chemical industry and personal care products, and relates to a cream preparation with high oil phase content and no emulsifier and a preparation method thereof. Background technique [0002] As we all know, cream preparation is a common preparation product for moisturizing and protecting the skin. It can instantly bring moisture and smoothness to the skin, and it can also bring moisture and protection to the skin for up to 12 hours, especially the high oil phase content Cream preparations generally contain 30% to 50% oil. Pharmaceutical preparations on the market are generally called ointments or creams. Cosmetics are generally called moisturizing creams or nourishing repair creams. It can give dry and dehydrated skin, sensitive peeling skin, Eczema dermatitis skin, photoaging and aging skin provide instant moisture and long-lasting protection. [0003] In the technical field of cream preparations, a hi...

AI Technical Summary

Problems solved by technology

There are also patents and literatures that mention the research on the preparation of cream emulsions by amphiphilic polymer macromolecules, but these studies are only limited to the use of amphiphilic polymers alone to achieve a certain emulsification by forming micelles, generally only emulsification is less than 30.0% content of the oil phase, and when emulsifying 30% of the oil phase, the amount of polymer used is generally greater than 1.0%, and 1.0% of the amphiphilic polymer will cause problems such as rubbing mud and other bad feeling of use in cosmetics, although there are also Data or studies have shown that single-use amphiphilic polymers can emulsify up to 50% of the oil phase, but the stability cannot meet the requirements of national standards, and the shelf life cannot be guaranteed. All amphiphilic polymers alone have not been seen on the market. Emulsify up to 50% of the oil phase of the deep moisturizing cream lotion and other preparations or cosmetics

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