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A kind of cream preparation with high oil phase content and no emulsifier and preparation method thereof

An emulsifier and high-oil phase technology, which is applied in the fields of medicine, chemical industry, and personal care products, can solve the problems of unguaranteed shelf life, unreachable stability, and bad feeling of use, so as to avoid the risk of skin irritation and enhance stability Effect

Active Publication Date: 2016-09-28
上海贝泰妮生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also patents and literatures that mention the research on the preparation of cream emulsions by amphiphilic polymer macromolecules, but these studies are only limited to the use of amphiphilic polymers alone to achieve a certain emulsification by forming micelles, generally only emulsification is less than 30.0% content of the oil phase, and when emulsifying 30% of the oil phase, the amount of polymer used is generally greater than 1.0%, and 1.0% of the amphiphilic polymer will cause problems such as rubbing mud and other bad feeling of use in cosmetics, although there are also Data or studies have shown that single-use amphiphilic polymers can emulsify up to 50% of the oil phase, but the stability cannot meet the requirements of national standards, and the shelf life cannot be guaranteed. All amphiphilic polymers alone have not been seen on the market. Emulsify up to 50% of the oil phase of the deep moisturizing cream lotion and other preparations or cosmetics

Method used

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  • A kind of cream preparation with high oil phase content and no emulsifier and preparation method thereof
  • A kind of cream preparation with high oil phase content and no emulsifier and preparation method thereof
  • A kind of cream preparation with high oil phase content and no emulsifier and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The specific formula is as follows:

[0033]

[0034]

[0035] Among the above components, the acrylic (ester) / C10-30 alkanol acrylate cross-linked polymer is selected from Lubrizol Company, trade name: Pemulen TR-2; the xanthan gum is selected from CP Kelco, trade name: KELTROLCG -SFT; Sodium Hyaluronate is selected from South Korea Bioland Company, trade name: Bio Sodium HyaluronateMMW; Pentylene Glycol is selected from Dezhixin Company, trade name: 5; Glyceryl polyether-26 is selected from Laibokang Company, trade name: Liponic EG-1; Sorbitan caprylate is selected from Clariant Company, trade name: VelsanSC; squalane is selected from Spanish caroiline, trade name: EXOLIVE; new Pentylene glycol dicaprylate / dicaprate was selected from DUBOIS Company, brand: DUB DONPG; jojoba seed oil was selected from Hallstar Company, product brand: J0010RG; glycerin was selected from Corning Chemical, trade name: Glycerine 99.5%.

[0036] Concrete preparation steps are as fol...

Embodiment 2

[0043] The specific formula is as follows:

[0044]

[0045] Concrete preparation steps are identical with embodiment 1.

Embodiment 3

[0047]

[0048]

[0049] Concrete preparation steps are identical with embodiment 1.

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Abstract

The invention discloses a cream preparation with high oil phase content and no emulsifier and a preparation method thereof, which comprises the following components by weight percentage: A component: acrylic acid (ester) / C10-30 alkanol acrylate Cross-linked polymer 0.30-0.40%, xanthan gum 0.10-0.20%, sodium hyaluronate 0.10-0.30%; component B: pentylene glycol 3.0-5.0%, glycerol polyether-263.0-8.0%, sorbitan Ester 0.5-1.0%; C component: squalane 15.0%-20.0%, neopentyl glycol dicaprylate / dicaprate 10.0%-20.0%, jojoba seed oil 5.0%-10.0%; D Components: 3.0-5.0% glycerin, 30.1-60.0% water; based on 100% cream preparation, the A component is 0.5-0.9%, the B component is 6.5-14.0%, and the C Divided into 30.0-50.0%, the D component is 35.1-63.0%. The invention can emulsify 30% to 50% of the oil phase content, replace about 5% of traditional emulsifiers and about 8% of natural emulsifiers, and avoid the potential skin irritation caused by a large amount of emulsifiers.

Description

technical field [0001] The invention belongs to the fields of medicine, chemical industry and personal care products, and relates to a cream preparation with high oil phase content and no emulsifier and a preparation method thereof. Background technique [0002] As we all know, cream preparation is a common preparation product for moisturizing and protecting the skin. It can instantly bring moisture and smoothness to the skin, and it can also bring moisture and protection to the skin for up to 12 hours, especially the high oil phase content Cream preparations generally contain 30% to 50% oil. Pharmaceutical preparations on the market are generally called ointments or creams. Cosmetics are generally called moisturizing creams or nourishing repair creams. It can give dry and dehydrated skin, sensitive peeling skin, Eczema dermatitis skin, photoaging and aging skin provide instant moisture and long-lasting protection. [0003] In the technical field of cream preparations, a hi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/92A61K8/81A61K8/73A61K8/02A61Q19/00
Inventor 李冰苏温柔马骁高绍阳何黎郭振宇
Owner 上海贝泰妮生物科技有限公司
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