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Sperm morphology anomaly detection method

A detection method and morphological abnormality technology, applied in image analysis, image enhancement, instruments, etc., can solve the problems of lack of head acrosome boundary detection, limitation of segmentation methods, etc., achieve good objectivity, easy verification and verification, and improve detection efficiency Effect

Inactive Publication Date: 2015-01-07
SHANDONG UNIV
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Problems solved by technology

However, the segmentation method is limited to boundary segmentation, and lacks the boundary detection of the acrosome and middle segment of the head

Method used

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  • Sperm morphology anomaly detection method
  • Sperm morphology anomaly detection method
  • Sperm morphology anomaly detection method

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Embodiment Construction

[0042] In order to better understand the technical solution of the present invention, the present invention will be further described below in conjunction with the accompanying drawings.

[0043] After the sperm are dyed with chemical reagents, they lose their activity, and then the morphological image of the sperm under the 100-fold microscope can be taken through the OLMPUS microscope. After collection, the morphological image of the untreated sperm is as follows figure 1 .

[0044] After image preprocessing and image segmentation, the rough outline and position of each sperm can be obtained from the morphology image of the sperm to be processed. Then, after initialization of the sperm contour sequence, the contour recognition based on the Snake model is carried out to obtain the precise contour of the sperm. Finally, the precise contour of the sperm is used for further head segmentation, neck segmentation and calculation of related parameters. The specific process is as ...

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Abstract

The invention discloses a sperm morphology anomaly detection method which is highly objective, capable of facilitating verification and improving detection efficiency, and broad in application prospect. The method comprises the steps of (1) acquiring the image of a sperm processed with a chemical reagent; (2) preprocessing the acquired image, wherein graying, contrast enhancement, image smoothing and denoising and binarization are conducted; (3) segmenting the preprocessed image, wherein impurity filtering and target extraction are conducted on the binarized image; (4) conducting profile identification so that the accurate overall sperm target profile and head profile can be obtained; (5) obtaining all parameter values so that relevant parameters of the sperm morphology can be directly judged.

Description

technical field [0001] The invention relates to a method for detecting abnormal sperm morphology. Background technique [0002] The basic process of the usual morphological detection is that medical workers treat the semen with a dye, and then observe it through a 100-fold microscope to artificially classify and count the morphologies. Conventional detection methods are greatly affected by conditions such as the detection environment, the experience and level of inspectors, and are time-consuming, laborious, and inaccurate, which can easily cause errors in detection results and bring difficulties to clinical treatment and scientific research. [0003] Computer-aided sperm morphology analysis is to stain the sperm with a dye to inactivate the sperm, and then collect the static sperm image through the image acquisition system, and finally use the algorithm to realize the detection of the sperm morphology. The detection parameters of this method mainly include sperm morphology...

Claims

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Application Information

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IPC IPC(8): G06K9/00G06K9/34G06K9/36
CPCG06T7/0012G06T7/149G06T7/155G06T2207/10056G06T2207/20024G06T2207/20036G06T2207/30004
Inventor 刘伯强刘忠国刘广宇边京华李卫宾刘肖肖
Owner SHANDONG UNIV
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