A traditional Chinese medicine composition for treating hyperosteogeny and preparation method thereof

A technology for bone hyperplasia and composition, applied in the directions of drug combination, pharmaceutical formulation, drug delivery, etc., can solve the problems of easy recurrence of disease and unsatisfactory treatment methods, and achieve the effects of improving clinical symptoms, low cost and good taste.

Active Publication Date: 2016-12-07
陈国志
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, practice has proved that these treatment methods are not ideal, they only treat the symptoms but not the root cause, and the disease is prone to relapse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Example 1 Oral liquid

[0064] Weigh out 0.6 kg of scutellaria, 2.5 kg of maple lotus, 0.6 kg of sea breeze vine, 0.6 kg of fenugreek, 1.5 kg of trombone, 2 kg of yellow water lotus, and 0.5 kg of perilla. Take 7 herbs, add water to extract twice, the amount of water for the two times is 10 times and 8 times the total weight of the herbs respectively, the extraction time for the two times is 2 hours and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated to 80 ℃ To prepare an extract with a relative density of 1.10, add excipients mannitol, sorbic acid and water to the extract, stir evenly, and divide the package to prepare an oral liquid.

Embodiment 2

[0065] Example 2 Tablet

[0066] Weigh out 2kg of L. vines, 5kg of fenugreek pears, 2kg of sea breeze rattan, 2kg of Fufangteng, 4kg of trombone, 4kg of yellow water lotus, and 2kg of perilla. Take 7 medicinal materials and extract 3 times with 40% ethanol. The amount of ethanol each time is 10 times, 8 times and 4 times of the total amount of medicinal materials. The extraction time is 3 hours, 2 hours and 1 hour respectively. The extracts are combined and filtered. , the filtrate is concentrated at 60° C. when the relative density of the extract is 1.25, and the adjuvant starch, ethanol and talc are added to obtain the tablet.

Embodiment 3

[0067] Example 3 Granules

[0068] Weigh out 1kg of scutellaria, 3kg of fenugreek pear, 1kg of sea breeze vine, 1kg of fenugreek, 2kg of walking horse tire, 2.5kg of yellow water lotus, and 1kg of perilla. Take 7 herbs, add water and extract 3 times. The amount of water added for three times is equivalent to 12 times, 8 times, and 6 times the total weight of the herbs. Each extraction time is 3 hours, 2 hours, and 1 hour, respectively. Combine the extracts and filter them. When the filtrate was concentrated to 70°C, the relative density was 1.20, and ethanol was added to make the alcohol content 40%, left standing for 24 hours, filtered, and the filtrate was concentrated to the extract with a relative density of 1.10 when the filtrate was concentrated to 70°C, Add starch and dextrin, granulate, dry and granulate.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating hyperosteogeny and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials: Chinese starjasmine stem, dentiferous dendropanax root and stem, futokadsura stem, euonymus fortunei, giantleaf ardisia rhizome, polygala fallax hemsl and perilla nankinensis decue. The traditional Chinese medicine composition disclosed by the invention has the effects of expelling wind and removing damness, activating meridian, promoting blood circulation and stopping pain and has good treatment effect on the hyperosteogeny.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating hyperostosis and a preparation method thereof. Background technique [0002] Osteoarthritis, also known as proliferative osteoarthritis, osteoarthritis, etc., is due to the degeneration and degeneration of soft tissues such as cartilage, intervertebral discs, and ligaments that make up joints, the formation of bone spurs at the edges of joints, and synovial hypertrophy. , a disease that causes secondary bone hyperplasia, leading to joint deformation, and when subjected to abnormal loads, causing joint pain, limited movement and other symptoms. Bone hyperplasia is divided into primary and secondary. [0003] At present, there are many methods for the treatment of osteoarthritis, all of which have limitations: 1. Direct current drug iontophoresis. The direct current drug iontophoresis method fully exerts the effec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P19/08
CPCA61K9/0053A61K9/0087A61K9/0095A61K9/14A61K9/1652A61K9/2009A61K9/2013A61K9/2059A61K9/4858A61K9/4866A61K36/185A61K36/24A61K36/25A61K36/37A61K36/535A61K36/67A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 陈国志
Owner 陈国志
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