4 results about "Euonymus fortunei" patented technology

This invention belongs to the field of detection and analysis technology, specifically relating to a method for detecting chemical components in Euonymus fortunei or compound Euonymus fortunei mixture based on UPLC-QTRAP-MS / MS. This invention employs the UPLC-QTRAP-MS / MS analytical method, which can simultaneously determine the content of 15 components in Euonymus fortunei herb or 34 components in compound Euonymus fortunei mixture, and has been applied to the content determination of multiple batches of compound Euonymus fortunei mixture. Systematic methodological validation has shown that this method has good precision, repeatability, and accuracy, meeting the requirements of multi-component quantitative analysis. The content determination results provide strong scientific evidence for establishing more scientific and reliable quality control methods and comprehensively and systematically evaluating the safety and rationality of its clinical use.

This invention discloses a compound moxa stick for warming yang and unblocking obstruction, its preparation method, and its application in improving reproductive system function. It belongs to the field of external preparations of traditional Chinese medicine. Addressing the problems of limited improvement effects of pure moxa sticks, lack of systematic design in compound moxa stick formulations, unclear synergistic effects between components, large fluctuations in conditioning effects, and difficulty in balancing conditioning effects and safety, this invention uses specific weight proportions of Artemisia argyi, Cyperus rotundus, Alpinia galanga, Cinnamomum cassia, Zingiber officinale, Illicium verum, Cinnamomum cassia twig, Spatholobus suberectus, Caesalpinia sappan, Smilax glabra, Euonymus fortunei, Citrus aurantium, Amomum villosum, Citrus reticulata peel, and Atractylodes lancea to prepare a compound moxa stick. The components synergistically enhance each other, and this product is used to prepare a moxibustion intervention product for improving the reproductive function of mammals. It can stably improve female ovarian reserve function and male asthenospermia, simultaneously regulate reproductive-related hormone levels, repair pathological damage to reproductive organs, and improve the quality of reproductive cells.

This invention discloses an HPLC method for the simultaneous determination of five components—protocatechuic acid, verbascoside, argentin, verbascoside, and argentin—in Compound Euonymus fortunei Capsules. The chromatographic conditions used are as follows: an Acclaim 120-C18 column (250 mm × 4.6 mm, 5 μm) is used, with acetonitrile-0.2% phosphoric acid solution as the mobile phase, gradient elution, and a flow rate of 1 ml / min. ‑1 The column temperature was 30℃, and the detection wavelength was 254nm. Under these chromatographic conditions, the linear ranges for the five components were: protocatechuic acid Y = 11726348.35x + 87150.17; (R 2 =0.9999), verbascoside Y = 27134X - 0.5781; (R 2 =0.9994), stigmoside Y = 29605X + 14.0030; (R 2 =0.9996), verbascoside Y = 51970X - 25.7380; (R 2 =0.9991), styracin Y = 61726X + 7.1802; (R 2 =0.9991). The chromatographic peaks of protocatechuic acid, verbascoside, gentianin, verbascoside, and gentianin were well separated, and the concentration and peak area showed a good linear relationship. This method is simple, rapid, accurate, and reproducible, and can provide a theoretical basis for the quality of Compound Euonymus fortunei Capsules.

The invention discloses a method for establishing a fingerprint spectrum of a wintercreeper medicinal material, and belongs to the technical field of pharmaceutical analysis. The establishment method comprises the following steps: (1) preparing a test solution and a reference solution; and (2) carrying out HPLC (High Performance Liquid Chromatography) analysis on the test solution and the reference solution to obtain the euonymus fortunei medicinal material fingerprint spectrum formed by common characteristic peaks. According to the invention, a high performance liquid chromatography (HPLC) technology is adopted, the euonymus fortunei medicinal material is taken as a detection object, and the HPLC fingerprint spectrum aiming at the euonymus fortunei medicinal material is established. The fingerprint spectrum contains 10 common characteristic peaks including protocatechuic acid, caffeic acid, astragalus smicus glycoside and afzelin, the quality of the euonymus fortunei medicinal material can be comprehensively evaluated, and a new technical thought is provided for quality control and quality evaluation of the euonymus fortunei medicinal material.