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Liver harmonizing cholagogue particles and preparation method of same

A technology for hepatitis and cholecystitis, applied in the field of Hegan Lidan Granules and its preparation, which can solve the problems of low curative effect and unsatisfactory curative effect

Inactive Publication Date: 2015-03-04
HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of Hegan Lidan Granules on the market is not ideal due to the composition and process, and the preparation is prepared by traditional technology, which has the disadvantage of low curative effect

Method used

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  • Liver harmonizing cholagogue particles and preparation method of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take 120g of Fangji, 100g of capillary, 67g of Citrus aurantium, 67g of Bupleurum, 100g of Scutellaria baicalensis, 67g of gardenia, 134g of Schisandra chinensis, grind them into 40 mesh coarse powder, put them in a circulating ultrasonic extractor, add 6550g of water, 6g of germanium powder, 6g Tween 60, select ultrasonic frequency 50KHz, extract with pressure 0.3Mpa for 30 minutes, filter with 80 mesh sieve to obtain extract; take extract and put it in jet spray dryer, control air inlet temperature 40°C, pressure 0.02Mpa, flow rate per second 400 meters to get nano-extract powder; take the extract powder, add lactose 400g, dextrin 100g, wet granulate with water, dry at 60°C, granulate, add 25g of talcum powder, mix well, and obtain Hegan Lidan Granules.

specific Embodiment 2

[0033] Take 120g of Fangji, 100g of capillary, 67g of Citrus aurantium, 67g of Bupleurum, 100g of Scutellaria baicalensis, 67g of Gardenia, 134g of Schisandra, crush them into 40 mesh coarse powder, put them in a circulating ultrasonic extractor, add 6550g of water, 8g of germanium powder, 10g Tween 60, select ultrasonic frequency 60KHz, extract with pressure 0.5 Mpa for 30 minutes, filter with 80 mesh sieve to obtain extract; take the extract and put it in a jet spray dryer, control the inlet air temperature at 50°C, pressure 0.04 Mpa, flow rate per second 600 meters away, get nano-extract powder; take the extract powder, add 400g of lactose, 100g of dextrin, wet granulate with water, dry at 60°C, granulate, add 25g of talcum powder, mix well, and make Hegan Lidan Granules.

Embodiment 3

[0035] Take 120g of Fangji, 100g of capillary, 67g of Citrus aurantium, 67g of Bupleurum, 100g of Scutellaria, 67g of Gardenia, 134g of Schisandra, crush them into 40 mesh coarse powder, put them in a circulating ultrasonic extractor, add 6550g of water, 7g of germanium powder, 8g Tween 60, select ultrasonic frequency 55KHz, extract with pressure 0.4Mpa for 30 minutes, filter with 80 mesh sieve to obtain extract; take the extract and put it in a jet spray dryer, control the inlet air temperature at 45°C, pressure 0.03Mpa, flow rate per second 500 meters to get nano-extract powder; take the extract powder, add lactose 400g, dextrin 100g, wet granulate with water, dry at 60°C, granulate, add 25g of talcum powder, mix well, and obtain Hegan Lidan Granules.

[0036] The above examples illustrate that Hegan Lidan granules can be prepared by adopting the extreme conditions and optimized conditions of the embodiments of the present invention. The actual effect of the present inventio...

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Abstract

The invention discloses liver harmonizing cholagogue particles and a preparation method of the same. The preparation method of the liver harmonizing cholagogue particles is characterized by comprising the following steps: smashing 120g of radix stephaniae tetrandrae, 100g of oriental wormwood, 67g of fructus aurantii, 67g of radix bupleuri, 100g of scutellaria baicalensis, 67g of jasmine and 134g of schisandra chinensis into coarse powder, putting the coarse powder into a circular ultrasonic extraction device, adding water, germanium powder and Twain 60, carrying out jet flow spray drying to obtain nano extract powder, and adding lactose and dextrin to obtain the liver harmonizing cholagogue particles, wherein the obtained liver harmonizing cholagogue particles are used for treating acute icteric hepatitis, a chronic hepatitis active stage and an acute and chronic cholecystitis, curative effect is obviously better than that of commercially available liver harmonizing cholagogue particles, and a good effect is obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to Hegan Lidan Granules and a preparation method thereof. Background technique [0002] Hegan Lidan Granule clears heat and dampness, soothes the liver and regulates qi. For acute icteric hepatitis, active chronic hepatitis, acute and chronic cholecystitis. The curative effect of commercially available Hegan Lidan Granules is not ideal due to the composition and process, and the preparation is prepared by traditional techniques, which has the disadvantage of low curative effect. Contents of the invention [0003] In order to overcome the above disadvantages, the present invention provides Hegan Lidan granules with high curative effect and a preparation method thereof. [0004] Invention embodiment is as follows: [0005] Take 120g of Fangji, 100g of capillary, 67g of Citrus aurantium, 67g of Bupleurum, 100g of Scutellaria baicalensis, 67g of gardenia, 134g of schisa...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/752A61K9/16A61P1/16
CPCA61K36/59A61K9/1652A61K36/233A61K36/28A61K36/539A61K36/57A61K36/744A61K36/752A61K36/79
Inventor 不公告发明人
Owner HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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