Kit for detecting relevant autoantibody spectrum of autoimmune liver disease

Abstract

The invention discloses a kit for detecting the relevant autoantibody spectrum of an autoimmune liver disease, and belongs to the technical field of biology. The kit comprises a membrane strip, an enzyme label liquid, a substrate and an enzyme label incubation buffer liquid, wherein the membrane strip is composed of a fixed plate as well as an antigen strip, a critical quality control strip and a functional quality control line which are sequentially fixed on a nitrocellulose membrane, wherein the antigen strip is formed by drawing 8 or 6 mutually independent drawing lines in AMA-M2, LKM-1, LC-1, SLA, F-action, gp210, Sp100 and La / SS-B on the nitrocellulose membrane. The kit can be used for detecting 8 relevant antibodies of the autoimmune liver disease, and can act as a basis for auxiliary diagnosis. The additionally arranged La / SS-B strip can be used for differentiating the autoimmune liver disease and liver injury caused by sicca syndrome, and thus providing a basis for the correct dosage regimen.

Description

technical field

[0001] The invention belongs to the field of biotechnology, and relates to a kit for diagnosing diseases, in particular to a kit for detecting autoantibody spectrum related to autoimmune liver disease. Background technique

[0002] Autoimmune liver disease is a kind of chronic progressive liver disease with unknown etiology, which is urgently related to autoimmune reaction, with hidden early clinical manifestations, and it is difficult to distinguish it from chronic viral hepatitis. The treatment methods of these two diseases are very different. If the treatment Improper treatment can eventually lead to liver fibrosis and cirrhosis, and the life of the patient can only be prolonged by liver transplantation. Therefore, early diagnosis and differential diagnosis of autoimmune liver disease is very urgent and necessary. Autoimmune liver diseases have specific antibodies, which are an important basis for early diagnosis and differential diagnosis of diseases. ...

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