116 results about "Autoimmune liver disease" patented technology

The invention discloses a kit for joint or single detection of an autoimmune liver disease related antibody, and a method for quantitative and qualitative detection of the autoimmune liver disease related antibody by using the kit. A sample is combined with a specific antigen which is connected with IgG or / and anti-human IgM or / and anti-human IgA of a label and corresponds to a detection antibody, a substrate of a luminescent system or a color development system or an exciting light system is added, then the signal value of the sample to be tested is read, and a quantitative or qualitative result is calculated or the quantitative or qualitative result is read through an immuno-chromatographic or an immuno-percolation method naked eye or an instrument, so that the type and the severity of an autoimmune liver disease are accurately diagnosed, medication performed by doctors is guided, and the method is high in sensitivity, strong in specificity and high in accuracy, and is suitable for a semi-automatic or full-automatic detection system or naked eye interpretation.

The invention discloses a compound composition of traditional Chinese medicine granules for regulating liver regeneration and prevention and treatment methods for chronic liver diseases by using the compound alone or in combination with antiviral medicine. The medicine is composed of: 5-30 parts of prepared Chinese foxglove root, 5-30 parts of virgate wormwood, 3-9 parts of turmeric, 3-12 parts of licorice, 3-15 parts of schisandra fruit, 5-15 parts of underleaf pearl, 5-30 parts of diffusa , 5-30 parts of poria, 5-30 parts of coix seed, 5-30 parts of salvia fruit, 1-10 parts of curcuma rhizome, 3-12 parts of dodder, and 5-15 parts of mistletoe For people suffering from chronic liver diseases (drug-induced liver disease, alcoholic or non-alcoholic fatty liver disease, autoimmune liver disease, viral hepatitis, etc.) which have high risk of liver failure, liver cirrhosis, and liver cancer, and people suffering from liver cancer or people after liver cancer surgery, clinical and experimental evidences show that the traditional Chinese medicine granules have synergies of regulation of liver regeneration and anti-virus, anti-liver injury, anti-liver fibrosis, and liver cancer prevention, and a relatively high level of clinical evidence based medicine evidences are obtained.

The invention relates to an antagonist of CB1 receptor for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders; inflammatory diseases; cardiovascular diseases; nephropathies; glaucoma; spasticity; cancer; osteoporosis; metabolic disorders; obesity; addiction, dependence, abuse and relapse related disorders; psychiatric and neurological disorders; neurodegenerative disorders; autoimmune hepatitis and encephalitis; pain; reproductive disorders and skin inflammatory and fibrotic diseases.

The invention discloses a kit for detecting LC-1 antibody relative to autoimmune liver diseases, and a quantitative and quantitative detection method for the LC-1 antibody with the kit. The detection method comprises the following steps of: combining a sample with IgG or / and anti-human IgM or / and anti-human IgA, which is / are connected with marker(s), and specific antigen corresponding to the detected antibody; adding a substrate of a luminescence system or a developing system or a light exciting system into the sample, and then reading a signal value of the sample to be detected; and calculating a quantitative and quantitative result or reading a quantitative and quantitative result of the sample by naked eyes or instruments according to immunochromatography or immuno-infiltration, thereby accurately diagnosing the type and severity of the autoimmune liver diseases to guide a doctor to dispense medicines. The quantitative and quantitative detection method has the advantages of high sensitivity, strong specificity and high accuracy, and is applicable to interpretation by semi-automatic or full-automatic detection systems or naked eyes.

The invention provides an autoimmune hepatitis risk prediction model and a construction method thereof. According to the construction method, noninvasive clinical data are collected and multi-factor logistic regression analysis is performed by selecting and classifying unknown-cause liver damage cases to obtain risk factors and decision coefficients of AIH, and a logistic regression model for predicting the autoimmune hepatitis risk is obtained, or an autoimmune hepatitis risk prediction nomogram model is established by the logistic regression. The autoimmune hepatitis risk prediction model provided by the invention can be used for early risk prediction of AIH of a patient with unknown-cause liver damage, has higher resolution, accuracy and clinical application value, is helpful for doctors to effectively persuade the patient with unknown-cause liver damage to receive the suggestion of liver biopsy as soon as possible, and enables the real patient with autoimmune hepatitis to be diagnosed and treated properly.

The invention discloses a kit for detecting LKM (anti-liver-kidney microsomal antibody)-1 relative to autoimmune liver diseases, and a quantitative and quantitative detection method for the LC-1 antibody with the kit. The detection method comprises the following steps of: combining a sample with IgG or / and anti-human IgM or / and anti-human IgA, which is / are connected with marker(s), and specific antigen corresponding to the detected antibody; adding a substrate of a luminescence system or a developing system or a light exciting system into the sample, and then reading a signal value of the sample to be detected; and calculating a quantitative and quantitative result or reading a quantitative and quantitative result of the sample by naked eyes or instruments according to immunochromatography or immuno-infiltration, thereby accurately diagnosing the type and severity of the autoimmune liver diseases to guide a doctor to dispense medicines. The quantitative and quantitative detection method has the advantages of high sensitivity, strong specificity and high accuracy, and is applicable to interpretation by semi-automatic or full-automatic detection systems or naked eyes.