Traditional Chinese medicine composition for treating autoimmune hepatitis and preparation method of traditional Chinese medicine composition

An autoimmune and composition technology, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations with non-active ingredients, etc., can solve the unsatisfactory clinical treatment effect of autoimmune hepatitis, the toxic and side effects of chemical drugs, and the high cost of treatment. Effects and other issues, achieve significant therapeutic and preventive effects, low toxic and side effects, simple and convenient quality control

Inactive Publication Date: 2015-04-29
邹士东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the above-mentioned therapeutic drugs have unsatisfactory clinical therapeutic effects on autoimmune hepatitis, and the toxic side effects and high therapeutic effects of chemical drugs often make patients miserable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 A traditional Chinese medicine composition for the treatment of autoimmune hepatitis and its preparation method

[0023] A traditional Chinese medicine composition for the treatment of autoimmune hepatitis, which is prepared from the following traditional Chinese medicine components in weight Kg: Alisma 45Kg, Gentiana 5.5Kg, Tripterygium wilfordii 30Kg, Scutellaria barbata 25Kg, Epimedium 30Kg, Acanthopanax 85Kg, Hedyotis diffusa 15Kg, Pueraria 12Kg, Corydalis 5Kg, lotus leaf 9Kg, astragalus 10Kg, curculigo 6Kg, licorice 10Kg.

[0024] A preparation method for a Chinese medicine composition for autoimmune hepatitis treatment, comprising the steps of:

[0025] (1) Soak tripterygium wilfordii, epimedium, kudzu root and astragalus in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin to obtain clathrate substances, clathrates and...

Embodiment 2

[0029] Example 2 A traditional Chinese medicine composition for the treatment of autoimmune hepatitis and its preparation method

[0030] A traditional Chinese medicine composition for the treatment of autoimmune hepatitis, which is prepared from the following traditional Chinese medicine components with a weight of Kg: Alisma 60Kg, Gentiana 7Kg, Tripterygium wilfordii 40Kg, Scutellaria barbata 30Kg, Epimedium 35Kg, thorns Five plus 90Kg, Hedyotis diffusa 20Kg, Pueraria 15Kg, Corydalis 10Kg, lotus leaf 15Kg, Astragalus 15Kg, curculigo 9Kg, licorice 15Kg.

[0031] A preparation method for a Chinese medicine composition for autoimmune hepatitis treatment, comprising the steps of:

[0032] (1) Take tripterygium wilfordii, epimedium, kudzu root and astragalus and soak in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin to obtain clathrate substanc...

Embodiment 3

[0036] Example 3 A traditional Chinese medicine composition for the treatment of autoimmune hepatitis and its preparation method

[0037] A traditional Chinese medicine composition for the treatment of autoimmune hepatitis, which is prepared from the following traditional Chinese medicine components in weight Kg: Alisma 52.5Kg, Gentiana 6.5Kg, Tripterygium wilfordii 35Kg, Scutellaria barbata 27.5Kg, Epimedium 32.5Kg, Acanthopanax 87.5Kg, Hedyotis diffusa 17.5Kg, Pueraria 13.5Kg, Corydalis 7.5Kg, Lotus leaf 12Kg, Astragalus 12.5Kg, Curculigo 7.5Kg, Licorice 12.5Kg.

[0038] A preparation method for a Chinese medicine composition for autoimmune hepatitis treatment, comprising the steps of:

[0039] (1) Take tripterygium wilfordii, epimedium, kudzu root and astragalus and soak in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then clathrate it with β-cyclodextrin to obtain clathra...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating autoimmune hepatitis, and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine components in parts by weight: 45-60 parts of rhizoma alismatis, 5.5-7 parts of radix gentianae, 30-40 parts of tripterygium wilfordii hook. f, 25-30 parts of herba scutellariae barbatae, 30-35 parts of herba epimedii, 85-90 parts of radix et caulis acanthopanacis senticosi, 15-20 parts of herba hedyotis, 12-15 parts of radix puerariae, 5-10 parts of rhizoma corydalis, 9-15 parts of folium nelumbinis, 10-15 parts of radix astragali seu hedysari, 6-9 parts of rhizoma curculigins, 10-15 parts of radix glycyrrhizae. The traditional Chinese medicine composition is superior to the existing therapeutic drugs on the aspect of treating autoimmune hepatitis, and thus the traditional Chinese medicine composition is suitable for clinical popularization and use.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating autoimmune hepatitis and a preparation method thereof. Background technique [0002] With the improvement of understanding and diagnosis level, the prevalence of autoimmune liver disease reported at home and abroad is increasing year by year, so it has been paid more and more attention and attention. It mainly includes: autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis, and any overlap syndrome between any two of these three diseases, often accompanied by extrahepatic immune diseases, and Diagnosis is based on specific biochemical abnormalities, autoantibodies, and dry tissue features. Among them, autoimmune hepatitis is the most common, and its liver tissue changes are consistent with chronic viral hepatitis, but the serum virus markers are negative. [0003] Autoimmune hepatitis...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P1/16A61P37/02
CPCA61K36/884A61K9/1652A61K36/254A61K36/296A61K36/37A61K36/481A61K36/484A61K36/488A61K36/515A61K36/539A61K36/62A61K36/65A61K36/66A61K36/71A61K36/748A61K36/88A61K47/6951A61K2236/15A61K2236/331A61K2236/333A61K2236/39
Inventor 张景英
Owner 邹士东
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