Brain activity training device and brain activity training system

A technology of training device and training system, applied in the field of brain activity training system, can solve problems such as sufficient research on functional connections

Active Publication Date: 2015-12-23
ATR ADVANCED TELECOMM RES INST INT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the conventional rs-fcMRI method is used to observe the activities of global neural networks such as the default mode network as described above, and it cannot be said that more detailed functional connections have been sufficiently studied

Method used

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  • Brain activity training device and brain activity training system
  • Brain activity training device and brain activity training system
  • Brain activity training device and brain activity training system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0104] figure 1 is a schematic diagram showing the overall configuration of the MRI apparatus 10 .

[0105] Such as figure 1 As shown, the MRI apparatus 10 is equipped with: a magnetic field applying mechanism 11, which applies a controlled magnetic field to the region of interest of the subject 2 and irradiates RF (radio frequency) waves; a receiving coil 20, which receives the response wave from the subject 2 (NMR signal) and output an analog signal; the drive unit 21 controls the magnetic field given to the subject 2 and controls the transmission and reception of RF waves; and the data processing unit 32 sets the drive unit 21 control timing, and process various data signals to generate images.

[0106] In addition, here, the central axis of the cylindrical bore (Bore) on which the subject 2 is placed is defined as the Z-axis, the horizontal direction perpendicular to the Z-axis is defined as the X-axis, and the vertical direction perpendicular to the Z-axis is defined ...

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Abstract

Provided is a brain activity training device for performing a training modifying correlation of connectivity between brain areas, using correlation of measured connectivity between brain areas in feedback information. A correlation matrix is derived for the activity degree between predetermined brain regions for each subject, from data of functional connectivity MRI at rest measured in a group of healthy subjects and in a group of patients (S102). Feature extraction is performed (S104) by regularized canonical correlation analysis on the correlation matrix and on subjects characteristics containing subjects patients / healthy labels. Based on the results of the regularized canonical correlation analysis, a discriminatory analysis (S106) is performed by sparse logistic regression and discriminants are generated (S108). The brain activity training device gives a score in feedback to subjects, based on the results of discriminants for data of functional connectivity MRI relative to the subjects.

Description

technical field [0001] The invention relates to a brain activity training device and a brain activity training system using brain function imaging method. Background technique [0002] (Biomarker) [0003] Indices obtained by digitizing and quantifying biological information in order to quantitatively grasp biological changes in a living body are called "biomarkers". [0004] The FDA (Food and Drug Administration of the United States) defines biomarkers as "items that are objectively measured and evaluated as indicators of normal physiology, pathophysiology, or pharmacological response to treatment." In addition, biomarkers that characterize the state, change, or degree of cure of a disease are used as surrogate markers for confirming the effectiveness of new drugs in clinical trials. Blood sugar level, cholesterol level, etc. are representative biomarkers as indicators of lifestyle-related diseases. It includes not only substances derived from living organisms contained ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055A61B5/375
CPCA61B5/055A61B5/7246A61B5/4064G01R33/4806A61B2576/026G06T7/0016G06T2207/10016G06T2207/10088G06T2207/30016G16H50/20A61B5/0036A61B5/316A61B5/375A61B5/7264A61B2560/0475
Inventor 川人光男森本淳八幡宪明桥本龙一郎福田恵柴田和久今水宽渡边武郎佐佐木由香加藤进昌笠井清登
Owner ATR ADVANCED TELECOMM RES INST INT
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